We compared patients with normal or reduced hemoglobin serum levels as a marker for anemia and identified a clear trend toward a better L3SMI in non-anemic patients ( p = 0.074; Figure 2 E).
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Smooth pursuit gain was not significantly different between DBS ON and DBS OFF for the 10°/s velocity, though a clear trend of increased smooth pursuit gain with DBS ON was observed (p = 0.074).
In the present work, we could find a clear trend (p = 0.0742) towards an increase of iEOS in SEA vs.
While AKT2: rs892119 indicated a clear trend to have reduced risk of distant failure when patients carried at least one variant allele (HR = 0.579, 95% CI = 0.317–1.057, P = 0.075).
When comparing all 3 months of each year, only a clear trend was detected towards LVEF<50% for the COVID-19 period ( P =0.075, df=4, Pearson’s chi-square=6.342) ( Figure 1B ).
When particularizing in each subscale of emotional intelligence ( Table 5 ), it was observed that the time dedicated to self-care was mainly related to better levels of repair; although this relationship did not become statistically significant, a clear trend was observed ( p = 0.075).
Of note, a clear trend was observed with decreased PD1 + CD4 + Tregs at day 8 post ablation in TDLN in both slow and fast freeze groups ( P =0.076 and P =0.082, respectively Supplementary Table 2 ).
Although the specified significance threshold was not reached, there was a clear trend toward an improved predictive discrimination of the hybridized ML model with respect to the expert-based model in the test data (Concordance index, P value = .076; AUROC, P value = .731), while a significant difference was patent between the hybridized ML model and the calcium score-based model (Concordance index, P value = .014; AUROC, P value = .025).
However, a closer examination of their results reveals a clear trend toward increased risk in PsA patients treated with monoclonal anti-TNFα agents, with a hazard ratio of 1.53 (95% CI, 0.95–2.47, a borderline p -value = 0.077), a finding that did not reach statistical significance, likely due to the limited power of their smaller cohort.
Although this difference did not reach statistical significance, a clear trend was observed ( p = 0.078), with morning KSS scores exceeding evening scores by a mean of 2.5 points.
Global longitudinal strain showed a clear trend towards its reduction in patients with CA (−12 ± 5.5% vs. −19 ± 0.6%; p = 0.078), although differences were not statistically significant.
Although no statistically significant differences were found in the analysis of survival and antibiotic exposure, there was a clear trend toward longer survival in patients who did not require antibiotic treatment (mOS 23 months for non-use vs 12 months for use of antibiotics; p = 0.078).
A clear trend toward a higher fatality was noted in the older population (72.9% vs. 56.6%; p = 0.078).
A clear trend towards a higher mortality was noted in the older population (72.9% vs. 56.6%; p=0.078).
iii) No significant association was observed between a higher CTC number and tumor burden or smoking status; however, a clear trend toward a correlation between an increased CTC detection rate and increased tumor diameter was observed (<3 cm, 48.7% vs. ≥3 cm, 71.1%; P=0.078).
Furthermore, in the PPPs of these liver cases and controls, the expression of miR-122 was significantly greater (p < 0.01, fold change = 3.3) and miR-200a showed a clear trend towards significance (p = 0.079, fold change = 4.5) in the liver cases compared to their matched controls, while, as expected, let-7e, which showed no association with liver disease in serum, showed no difference in the PPPs.
There was a clear trend towards shorter OS (4.7 (95% CI: 3.2–6.1) vs 11.3 (95% CI: 9.1–13.4) months, p=0.079) in patients with ABT vs without ABT ( Supplemental Figure 1 ).
There were no significant changes in PTH from baseline over the two years ( p = 0.08), but a clear trend of an increase over time ( p = 0.08).
In the group receiving IST, there was a clear trend towards lower mortality (23.8 vs. 53.8, p = 0.080) and a significant improvement in LVEF (29.8 ± 11.7 → 35.9 ± 13.9, p = 0.036 vs. 26.5 ± 11.9 → 33.6 ± 14.2, p = 0.208) compared to DCM patients with myocarditis who did not receive IST.
In a parallel testing of several anti-TF Ab isotypes (IgG, IgM, IgA, and a pool of all isotypes) only IgM showed a clear trend to a lower level in cancer ( n = 36) compared to healthy donors (0.22 ± 0.07 (SD) and 0.31 ± 0.2, resp., P = 0.08) and a significant decrease compared to the benign group (0.37 ± 0.12, n = 15, P < 0.001).
For male patients, there was a clear trend towards better OS ( p = 0.08), DFS ( p = 0.10), and FFR ( p = 0.09) in earlier tumors as well as significantly better CFS ( p = 0.04).
While the combination therapy did not reach statistical significance over chemotherapy alone, a clear trend toward improved response was observed (Cis vs Combo, p = 0.08), mirroring clinical observations in advanced NSCLC patients 85 , 86 .
Furthermore, besides the absence of statistical significance for the relationship between W PCr and rate of shots per rally of offensive style players, a clear trend can be assumed (i.e., r = 0.71, P = 0.08 and 1-β = 97%) and highlights the importance of W PCr development for athletes who wish to play the points with greater intensity, since rate of shots per rally could be a variable to represent intensity during table tennis matches.
The blood pressure was significantly reduced following surgery in both age groups, and the magnitude of blood pressure was not significantly different, although there was a clear trend towards greater reduction in systolic arterial pressure in older patients ( P = 0.08) ( Figure 4(D) ).
By contrast, in the HR+/HER2+ BC cohort we found no statistically significant association between BMI and RFS (hazard ratio 1.36; 95% CI: 0.61–3.07, p = 0.452), while hyperglycemia was associated with worse RFS at univariate analysis (hazard ratio 2.85; 95% CI: 1.02–8.00, p = 0.047), with a clear trend toward worse RFS also at multivariable analysis (hazard ratio 2.52; 95% CI: 0.89–7.1; p = 0.080) ( Figure 2 ; Table 4 ).