“a clear trend”

In addition, a negative correlation was found between mRD and ΔSUV using all patients (rho = −0.5238; p = 0.0005) and a clear trend for the mIR group (rho = −0.3924; p = 0.0519) but not the mIS group (rho = −0.0942; p = 0.7234) ( Figure 2 A–C).

Similarly, RO beads significantly improved visibility over LC Bead on CBCT in target arteries ( P =0.0238) and showed a clear trend towards better visibility in non-target arteries ( P =0.0519).

In univariable Cox regression analyses, there was a clear trend between higher CFS scores and need for mechanical ventilation during follow-up (HR 1.361, 95% CI 0.998 to 1.857, p=0.052; C-index 0.722), while there was a significant association between lower CFS scores and earlier discharge from hospital (HR 0.531, 95% CI 0.354 to 0.797, p=0.002; C-index 0.742).

Patients initially treated with ICI sowed a clear trend towards longer post-DM-survival of 20.7 (95% CI: 13.9–27.6) vs 7.8 (95% CI: 4.4–11.5) months ( p = 0.052).

In CLI patients the capability of diabetic CM to stimulate scratch wound closure showed a clear trend to be lower than that of non-diabetic CM (34.3% [11.7–41.3] vs 46.1% [35.1–51.9]; P = 0.052) no differences were observed between patients with Fontaine III or IV (P = 0.882).

To assess the role of bortezomib-based maintenance therapy specifically in patients after ASCT, we excluded the trial involving transplant-ineligible patients 24 and performed the meta-analysis again, which showed improved OS (HR = 0.72, 95% CI 0.54–0.96, P = 0.025) and a clear trend toward improved PFS (HR = 0.84, 95% CI 0.699–1.001, P = 0.052).

3d ), with a clear trend visible also for Oscillospiracaee ( P = 0.052).

UICC-stage thereby missed statistical significance, however, a clear trend could still be observed for advanced UICC-stages (III & IV) to impair the OS of tumor patients (HR 1.486; 95% CI 0.996–2.217, p = 0.052).

The OD shift of DR WT mice exhibited a clear trend for a reduction of deprived (contra) eye responses (no MD ≥P28 versus MD ≥P28, p = 0.052; Fig 3D and 3H and 3J ), whereas ipsi-evoked responses in V1 remained unchanged (no MD ≥P28 versus MD ≥P28, p = 0.74).

Additionally, a clear trend toward less local recurrence was observed for TRG0, with a cumulative incidence of 2.3% compared with 1.8% for TRG1, 5.2% for TRG2, and 15.6% for TRG3 ( P = 0.052, Figure 1 C).

When comparing both subgroups using a log-rank test, there was a clear trend toward a reduced OS in FLT3 -ITD HIGH patients ( P = 0.052).

However, for 10-year DMFS, a clear trend towards significance is observed in favour of longer time intervals ( P =0.052).

In patients with elevated NTproBNP levels (above 450 ng/mL[ 24 - 26 ]), high IL-6 levels were significantly associated htx/death ( P = 0.01) and a clear trend for increased incidence of MACE could be observed ( P = 0.052).

Interestingly, TPO levels between our severe and nonsevere COVID-19 cohorts showed a clear trend towards elevated circulating TPO in severe COVID-19 infection ( p = 0.052; Fig 3C ).

Thus, there was a clear trend that intermediate-phenotype males use higher proportion of identified Common Nightingale song types than sympatric Thrush Nightingale males, although marginally non-significant (GLM, DF1 = 1, DF2 = 12, F = 4.63, p = 0.052).

We segregated sequence read pairs into their short (centromeric) and long (telomeric) components and determined a clear trend ( P = 0.0524) toward higher error incorporation into the centromeric reads that may implicate DNA polymerase alpha ( Supplemental Fig. 7C ).

The 5-year survival rates showed a clear trend towards a superior survival time for patients treated with CIK cells ( P = 0.0526).

Patients were divided into three subgroups according to dynamic changes of EBV-DNA status: EBV-DNA persistently negative group (PNG, 24/58), EBV-DNA persistently positive group (PPG, 16/58), and EBV-DNA transformed from positive to negative group (TNG, 18/58); among the three groups, PPG had a clear trend toward worse PFS and OS ( P =0.0527 and P =0.0139, respectively) (Figure 1E, 1F).

hom p < 0.0001) and a clear trend toward the same effect in middle age, hom males (het vs. hom p = 0.0529).

In our SHF model there was a clear trend towards a decrease in creatine level (p = 0.053) amid otherwise unchanged profile of energy metabolism.

Among non-diabetic patients, carriers of the major DPP4 haplotype had significantly lower levels of blood glucose (P=0.003), insulin (P=0.034), and HOMA-IR index (P=0.007) along with a clear trend for lower glycated hemoglobin (P=0.053), while DPP4 activity was very reduced (P=0.046).

Using a linear mixed model with the change to baseline of Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) as a dependent variable, we found a clear trend towards significance for superiority of iCBIT ( n = 67) over placebo ( n = 70) (−1.28 (−2.58; 0.01); p = 0.053).

The highest DNA-copy number differed significantly between groups, with higher levels in VI, (p = 0.002) and a clear trend towards a difference in infection duration was also observed (p = 0.053).

Although ITGA11 did not reach statistical significance in the multivariate analysis, it showed a clear trend toward being an independent prognostic risk factor (hazard ratio [95% CI]: 2.024 [0.992–4.131], p = 0.053; Table S7 ).

After excluding data with CV >15 % there was a clear trend towards significance for a difference in TNF-α levels between women with and without tendinopathy ( p = 0.053, Table 5 ).