Excerpts

Among patients treated with sarilumab or tocilizumab, the difference in survival between the high- and low-risk groups was highly significant ( P < 0.0001).

The difference between the occupancy levels of these proteins in the two classes of CID boundaries is extremely significant ( Supplementary Figure S6B ; two-sample t -test P -values < 10 −4 in all cases).

The linear regressions on age were all very highly significant ( P < 0.0001), accounting for a minimum of 61% of the variance.

The difference was statistically extremely significant ( P < 0.0001).

Among the tested LV constructs, one miR-126 target (hereon referred to as hGALC_126T.LV) performed at best since it allowed a highly significant ( P < 0.0001) repression of hGALC activity in both CB- and BM-HSPCs at +1 day of culture ( Figure 1a ) and a sustained hGALC expression upon in vitro cell differentiation (after 14 days of liquid culture) ( Figure 1b ), in the presence of comparable vector copy number (VCN) values with the other tested constructs ( Supplementary Figure S1a ).

As shown in Table 2 , the model selected by the test was highly significant ( p < 0.0001).

With regard to CD, Faecal BAFF and calprotectin demonstrated highly significant correlation with SES-CD (Spearman’s rank correlation coefficient r = 0.579, p < 0.0001; r = 0.518, p = 0.003, respectively), as shown in Fig. 3A and B .

This difference between Austrian and Chinese beetles was highly significant ( t -test, p < 0.0001).

The spline model still fit in a comparable way to the covariate-only model (AIC 195 850 vs 196 551; ΔAIC ≈ 702), and a LRT confirmed a highly significant nonlinear PM 2 . 5 –DFI relationship ( χ 2 4 = 709.6, P < 0.0001).

Judging from the magnitudes of the log-hazard ratios, nodal status is more influential than the T stage in predicting survival, although both are highly significant ( p < 0.0001).

Heterogeneity was clearly significant for the pooled result of HbA1c ( df = 8, p < 0.0001, I 2 = 82%).

However, the “Day Post-Injury” is a highly significant factor (two-way ANOVA, α = 0.05, p < 0.0001), and in general demonstrates that the bluest shifted myelin (Day 21, Adult) was significantly different in PI than the most red-shifted myelin (Day 27,30). 3.1.2.

Non-musicians showed highly significant correlations at the group level for all pulse clarity-driven ICs ( p < 0.0001) except for IC 50 ( p = 0.06), whereas musicians exhibited significant correlations only for the four highest model orders [IC 70 ( p < 0.05), IC 80 ( p < 0.01), IC 90 ( p < 0.001), and IC 100 ( p < 0.005); see Figure 6B ].

The presence of AACA in infected groups, whether in patients coinfected with HIV and leprosy, or leprosy or HIV infection alone, was highly significant when compared with the control group ( P < 0.0001).

The differences in the distribution of major categories with respect to isolated/syndromic occurrence were statistically highly significant (p<0.0001).

Linear test for trend confirmed a dose–response pattern with a positive trend for both maternal income for narrow AN ( p < .03) and paternal income for narrow and broad AN (both p < .0001), but a negative trend for both maternal and paternal income for MDD (both p < .0001).

There was a highly significant effect of group on the accuracy difference (M - W), as indicated by ANOVA (F (2, 138) = 48.96, p < 0.0001).

The analysis revealed highly significant main effects of PCA concentration (F4,40 = 550.59, P < 0.0001) and fungal species (F3,40 = 30.32, P < 0.0001).

Consistent with this, analysis of data obtained from the Cancer Cell Line Encyclopedia [ 28 ] ( http://www.broadinstitute.org/ccle/home ) of 47 colon cancer cell lines for mRNA expression reported as a robust multi-array average (RMA) of CDCP1 and CD9 showed a highly significant positive correlation (p = 0.0001) between CDCP1 and CD9 mRNA expression by Pearson correlation analysis (Figure 2 D).

The association remained highly significant ( P < 0.0001 for all models) after adjustment for age, gender, and BMI in Model 2 (OR: 1.59, 95%CI: 1.45-1.74), additional ethnic/racial groups in Model 3 (OR: 1.65, 95%CI: 1.50-1.81), and all covariates in Model 4 (OR: 1.40, 95%CI: 1.27-1.54).

Comparable stomata frequencies were confirmed in the glucose and fructose treatments ( Figure 2B ), and there were highly significant differences with sugar-free conditions ( p -value <0.0001, Mann–Whitney's U-test).

Regarding heterogeneity, the Q-statistic was highly significant, where Q(df = 7) = 1892.2864 ( p < 0.0001), indicating substantial methodological variance across the included studies.

Overall, the analysis of the 4 × 4 contingency table constructed by treatments (columns) against groups of females was highly significant to accept the alternative hypothesis that there was a relationship between treatment and group of females (χ 2 = 104.78, df = 9, p < 0.0001).

The Kruskal–Wallis tests revealed the differences between the median von Mises stress values for each species to be highly significant ( p < 0.0001). 3.3.

Between groups analysis (PCOS, T2D and controls) showed a highly significant difference between the groups ( F = 63.43, p < 0.0001).