Excerpts

The regression coefficient associated with the number of trials between repetitions was negative and highly significant (p<0.0001; t-test, Equation 8 ).

FAS), we observed a marked and highly significant impairment of vascular function in the HFrD groups compared to their non-HFrD counterparts ( p < 0.0001 for all comparisons).

To define a locus associated with increased adiposity and protective effects on cardiometabolic traits, we retained only variants for which the single-trait GWASs for both traits reached marginal significance, defined as P < 10 −4 , and for which the association was opposite to the established phenotypic correlation.

The similarity between the two groups was also evaluated using PERMANOVA, which showed slightly significant differences between the HCC and control groups: p -value < 0.0001, but the pseudo-F value is low (pseudo-F = 1.43). 2.3.

Statistical analysis demonstrated a highly significant difference between the two groups (p = 0.0001).

This analysis also revealed a highly significant enrichment for TATA-box utilization in the G1 population of each gene set ( P < 0.0001, Fisher's exact test), albeit larger in the tissue specific population, alongside an enrichment in Sp1 binding site utilization in the tissue independent gene sets ( Supplementary Figure S6A and B ).

In a subsequent study, these findings were confirmed, revealing a highly significant correlation ( p < 0.0001) between PWVinv and cfPWV when using the notch-femoral carotid-notch path length estimation.

Results A highly significant association (p < 0.0001) was observed for joint space narrowing (JSN) as well as for osteophyte formation between the three groups.

We found a moderate and highly significant ( p < 0.0001) correlation between the frequency of MAITs expressing CD69 and the frequency of NK cells, CD4 + T cells and CD8 + T cells expressing CD69 across all the samples (Spearman r = 0.697 for CD69 + NK cells, r = 0.508 for CD69 + CD4 + T cells, r = 0.649 for CD69 + CD8 + T cells, Fig. 5 a).

For the index, the difference in MGMT expression between the high and low miRNA samples was highly significant at p<0.0001.

A linear mixed effect model analysis on maximum CC coefficients confirmed these impressions, finding a highly significant effect of partner, F (1,130) = 91.30, p < 0.0001.

The onset of TAO within 2 years after the treatment with RAI and the titer of TSHR-Abs The relation between the onset of orbitopathy symptoms in patients with GD during a two-year of follow-up after a therapeutic dose of 131 I and the titer of TSHR-Abs in the serum was highly significant ( P <0.0001).

In contrast, both TCEP- and saline-treated animals showed a highly significant increase in nasal airspace ( Figures 4B, C ; p < 0.0001; n = 29).

The within‐design heterogeneity is highly significant ( Q = 75.37, p < 0.0001).

Highly significant decrease in the VAS score and mean lesion size score was noted over the periods of follow up at 1, 2, 4 weeks and 2 months (p = 0.0001) when compared to topical corticosteroids.

Note that extremely significant p = 0.0001 to 0.001 is shown with ∗∗∗, very significant p = 0.001 to 0.01 with ∗∗, and significant p = 0.01 to 0.05 with ∗.

Interestingly, although GMMA from both STm G Δ msbB Δ pagP and SEn G Δ msbB Δ pagP contained only penta-acylated lipid A, they showed an approximately 3-fold difference in their potentials to elicit IL-6 release from human PBMC (3.15 ng/ml versus 0.89 ng/ml), which was highly significant ( P < 0.0001).

Interestingly, this difference, while being small, is highly significant (paired-sample t -test; N = 176 per group; p < 0.0001).

The ANOVA showed that the P -value for the regression model was highly significant ( P < 0.0001), while the model’s lack of fit was not significant ( P = 0.1138 > 0.05), indicating that the model effectively fitted the linear relationship between TFC from E. breviscapus and the tested factors.

SPLS model coupled with PFS analysis indicate highly significant difference at 6-month between the two patient strata for MM (100% R vs 15% NR, p<0.0001) and mUC (80% R vs 20% NR, p<0.01).

A full model ANOVA of stmscore detected a highly significant Genotype × Season interaction ( P < 0.0001), therefore separate ANOVAs for the Spring and Fall 2011 data sets were performed (Table 1 ).

The relationship between fish intake and blood mercury was highly significant ( p < 0.0001).

Quantitative IgG levels showed a highly significant inverse correlation with viral loads (p<0.0001) ( Figure ).

The “Model F -value” was highly significant, with only a 0.01% likelihood of being influenced by noise ( P < 0.0001) (Table S2 ).

Patients with bone pain at study inclusion demonstrated a distinct bone-centric disease pattern, characterized by highly significant increases in osteolytic lesions with structural instability risk (25% vs. 11%, p = 0.0001) and higher prevalence of CRAB-B already present at ID (90% vs. 78%, p = 0.003).