Excerpts

Twelve minutes after adding the drug significant (P<0.01) differences were detected between motility of sensitive and resistant lines, and from 6 hours onwards the difference was highly significant (P<0.0001).

The results demonstrate that essential oil type and concentration have a highly significant effect on the change in Phaeococcomyces cell count (p < 0.0001).

This synergy was confirmed through two-way analysis of variance and multiple t -tests, which showed highly significant interactions ( P < 0.0001)[ 33 , 48 ].

In the vector–mRNA group ( n = 16), the median ID 50 one month after prime vector-based vaccination (Vaxzevria ® ) was 143 (IQR = 112–254) and the median ID 50 one month after booster vaccination with an mRNA vaccine was 4978 (IQR = 3364–7508), which, when compared, was found to be a highly significant boost in neutralizing titers ( Figure 2 a, p < 0.0001, Wilcoxon t test).

However, 49 cases of co-infection were observed and 10 cases of infection with only Paramarteilia , a result that is highly significant (Chi-Square; χ 2 = 39.4, df = 1 P < 0.0001) and consistent with that found in a previous survey 13 .

This evident shift in median emergence time is highly significant (Friedman two-way ANOVA, p <.0001).

The presence of AACA in infected groups, whether in patients coinfected with HIV and leprosy, or leprosy or HIV infection alone, was highly significant when compared with the control group ( P < 0.0001).

Irf8 KO mice revealed a strikingly altered rMG distribution and morphology compared with wild-type (WT) animals, characterised by slightly reduced MG numbers in the inner plexiform layer (IPL, Irf8 WT: 104 ± 7 cells/mm 2 , Irf8 KO: 88 ± 5 cells/mm 2 , p = 0.09) and highly significant decrease of cell numbers in the outer plexiform layer (OPL, Irf8 WT: 116 ± 6 cells/mm 2 ; Irf8 KO: 43 ± 1 cells/mm 2 , p < 0.0001, Fig. 2 B,C).

ANOSIM analysis confirmed a highly significant difference among the four microbial community structures ( R = 0.81; P = 0.0001) and the performed test showed significant differences in the pairwise comparisons of the sites with R values approaching 1 in most of the cases ( Table 3 ).

Because the hand was travelling in a predominantly rightwards direction at cue onset (with the average speed in that direction 760% greater than upwards, and 490% greater than forwards), we expect the errors to be most prominent in azimuth angle ( Figure 1 B) For stimulation over the cerebellum, the 5.13° (±0.48° SEM) difference in azimuth was highly significant ( Figure 4 A, one-sample t -test, t (32)=10.58, p < 0.0001).

Highly significant differences were found between substrates in February (F = 5.217; df = 5, 114; p < 0.0001), April (F = 5.983; df = 5, 114; p < 0.0001), and August (F = 7.672; df = 5, 114; p < 0.0001); significant differences in June (F = 4.066; df = 5, 114; p < 0.01), December (F = 4.194; df = 5, 114; p < 0.01), and October (F = 2.948; df = 5, 114; p < 0.05).

Results: Natalizumab patients had a net improvement in disability over time (-0.15 EDSS years) while placebo had a net worsening (+0.33 EDSS years), as measured by LS mean AUC; the difference (0.48 EDSS years) was highly significant ( P < 0.0001).

( 5 ) Highly significant correlations were found between RT-PCR results and antigen levels (Pearson r = −0.61; p < 0.0001) ( Fig. 1 B ).

By metaphase, statistically highly significant EBV-IS ( p < 0.0001) were located on 13q21 (33 metaphases); 19q13 and 22q12 (16 metaphases); 1p35, 2p23, 2q31, 7p22, and 13p11 (15 metaphases); 3q26 and 7q21 (13 metaphases); 2q21, 4q21, and 4q34 (12 metaphases); 15q14, and 17q25 (11 metaphases); as well as 1q31 and 12q21 (eight metaphases).

Irradiated samples treated with 5-ALA of 50 or 100 μg/ml showed highly significant ( p < 0.0001) reductions in cell viability compared to the irradiated 5-ALA-free controls, decreasing progressively with increasing light doses from 0 to 32 J/cm 2 .

This result of zero overlapping genes given these two groups is highly significant ( p value < 0.0001) indicating that this result was not due to chance.

The decline close to the cell bodies was not significant (37 ± 3% to 26 ± 4%; Figures 3E and 4A ; t -test, P < 0.08; n = 31), but the three-fold decline at longer distances (>250 μm) was highly significant (14 ± 2% at P36 to P40 to 4 ± 1% at >P41; t -test, P < 0.0001).

The mean level of TIMP-1 in EDTA plasma from 143 patients with Dukes' stage D colorectal cancer was 240 ± 145 μg l −1 and a Mann–Whitney test demonstrated a highly significant difference between TIMP-1 levels in healthy blood donors and colorectal cancer patients ( P < 0.0001).

This is a highly significant difference, as compared to the 49% de novo CNVs in vivo (p < 0.0001, binomial test).

This change between the two groups was found to be highly significant ( P < 0.0001).

The analysis of variance of the response surface revealed that the model was extremely significant ( p < 0.0001), the lack of fit was not significant ( p > 0.05), the correlation coefficient R 2 was 0.9816, and the adjusted determination coefficients R adj 2 was 0.9632 ( Table 2 ).

Ground truth and MREyeTrack estimations were compared using linear regression analysis and yielded highly significant results (all p < 0.0001; Fig. 3 D ).

The overall effect of the model was highly significant ( p < 0.0001), indicating that NH 4 + , K + , NO 3 − , BAP, and NAA significantly affected growth.

Nevertheless, based on the data on dietary fat consumption in China over the past 30 years, we believe that there is a highly significant correlation ( p < 0.0001) between excessive fat intake and CVD.

The resulting quadratic model was statistically robust (R 2 = 0.874; adjusted R 2 = 0.845; p < 0.0001), with DNA:PEI ratio emerging as the dominant determinant of titre, supported by highly significant linear ( p < 0.0001) and quadratic ( p = 0.00028) terms.