Results In 53 studies of dystonia phenotypes, the proportion of men showed a highly significant negative association with mean age of onset ( p < 0.0001, pseudo- R 2 = 59.6%), with increasing female predominance from 40 years of age.
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Increasing education displayed a strong trend (Cochran-Armitage Trend Test, p<0.0001) with increasing levels of education associated with increased use of condoms, such that compared to men with less than four years of education, men with post-high school education were 13 times more likely to reported higher levels of condom use.
Accordingly, here we detected a significant reduction in Hsp90 transcript levels of both isoforms in TGFβ-activated fibroblasts treated with mKate2 10K-EVs-CTPRAu, and a highly significant reduction (****p < 0.0001) by mKate2 100K-EVs-CTPRAu, 36 h after administration of EVs on TGFβ-activated fibroblasts (Figure 4 C-E).
With a confidence value of α = 0.05, values p > 0.05 were considered statistically not significant (ns); those between 0.01 < p < 0.05 were considered significant (*); 0.001 < p < 0.01 were very significant (**); 0.0001 < p < 0.001 were extremely significant (***) as well as those p < 0.0001 (****). t-test was used to assess statistical differences between two sample means (two-tailed paired or unpaired, when appropriate).
ANOVA test observed highly significant differences to leaves against other plant parts ( F test = 134.24) ( P value < 0.0001).
An increasing trend was observed for neurological/psychological diseases (P value <0.0001).
The second-order similarity (i.e., correlation between pairwise cosine similarity matrices) between the McRae norms and the CSLB norms is highly significant (Spearman rho; for all 415 items, rho = .624, p < .0001).
Furthermore, 2.40 MBq 90 Y-DOTA-DAB4 given 24 hours after chemotherapy produced a highly significant extension of MST to 61 days ( P <0.0001 versus control, and P <0.001 versus any other treatment including 2.40 MBq 90 Y-DOTA-7E11 given 24 hours after chemotherapy; Figure 6B ).
The correlation between MMP-8 and sTREM-1 by the Spearman rank test was highly significant ( r = 0.8640, p < 0.0001; Figure 4 C).
The data indicate that the regression model is highly significant ( p < 0.0001), with a non-significant lack-of-fit term ( P = 0.9490 > 0.05), demonstrating a good fit and low experimental error.
ANOVA indicated that the model was highly significant ( p < 0.0001) with an insignificant lack of fit ( p = 0.3319 > 0.05), demonstrating good overall fitness.
This was highly significant (Fishers exact test, P = 0.0001) (Table I).
Statistical analysis demonstrated a highly significant difference between the two groups (p = 0.0001).
The P -values for the interaction terms between each of education level and wealth quintile and the time period variable were highly significant ( P <0.0001 in all models for both unadjusted and adjusted estimates).
During the dark phase of the dark/light cycle these differences were highly significant (all p < 0.0001) indicating that the states of vigilance in older mice were less consolidated compared to young mice.
Kaplan Meier analysis (Figure 3 a) showed the difference in DSS between risk groups to be highly significant (P = 0.0001, HR: 2.23 95 % CI: 1.46 to 3.50).
Chi-square was highly significant ( X 2 = 18,948.52, df = 253, p < 0.0001), indicating divergence of what was observed from the predicted model.
Differences between both targeting vectors and the control vector were highly significant (∗∗∗∗p < 0.0001), regardless of whether αG staining was performed with vWF or P-selectin ( Figure 3 C).
Variance in signed FA (δ 2 FA =0.4066) was more than tenfold larger than variance in ME (δ 2 ME =0.03085) and was highly significant (likelihood-ratio test: P <0.0001).
Thus, the Multivariate Linear Equation (MLE) of LFI as a function of the experimental conditions of S, pH and TA/S, yields a highly significant fit (p << 0.0001) as seen in the comparison between the measured LFI and the calculated LFI (Fig. 2 ).
One-way ANOVA followed by Tukey ’ s test demonstrated that the enrichment of TcIT in PM with respect to HG (160%) and TM (130%) was highly significant ( P < 0.0001 and P = 0.0001, respectively).
The score for heterogeneity across studies was highly significant for both resident studies (Q = 12306.4078; d = 37; P < .0001) ( Figure 2 ) and staff (Q = 1327.6350; d = 22; P < .0001) ( Figure 3 ).
As expected, there was a highly significant positive relationship between time post-blood meal and the proportion of mosquitoes showing ruptured oocysts (LRT χ 1 2 = 95 , p < 0.0001, figure 4 a ).
VRS showed an increasing trend with the severity of care, p < 0.0001.
The prevalence of monoparasitism (71.77%) compared to polyparasitism (28.23%) was extremely significant ( P <0.0001), while no significant difference according to gender was found ( P =0.2751).