Barely Significant

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At wave 2, all three scales were positively correlated; however, the correlation between neighborhood social ties and neighborhood safety was low in magnitude (0.031) and did not reach statistical significance (both other correlations were significant at the p < .0001 level).
highly significantp < 0.00010.0× alphaqualifiedgold
As shown in Additional file 1 : Figure S1, the correlation of eGDR calculated using this formula with glucose disposal rate (GDR) measured with euglycaemic-hyperinsulinemic clamp in 140 T2D patients was highly significant ( r = 0.624; p < 0.0001); moreover, it was higher than that of Homeostasis Model Assessment – Insulin resistance (HOMA-IR) in the 85 patients with calculable values ( r = 0.441; p < 0.0001) and similar to that reported in the validation study in T1D individuals [ 25 ].
highly significantP < 0.00010.0× alphaqualifiedgold
This showed that the effect of gene category (i.e., the difference in dN between genes encoding PRR and cytokines on one hand and those encoding signaling proteins and transcription factors on the other) remained highly significant ( F = 42.9, df = 3, 304, P < 0.0001) even when controlling for a negative correlation between sequence divergence and pleiotropy ( F = 5.04, df = 1, 304, P = 0.026), and an interaction between gene category and expression divergence ( F = 3.41, df = 3, 304, P = 0.018; see supplementary table S1 , Supplementary Material online for full model details).