Excerpts

A post-hoc analysis revealed a moderate, but highly significant negative correlation between time from disease onset to diagnosis and disease progression rate (Spearman r = − 0.4798; p < 0.0001).

In contrast, cells expressing E2814-CAR exhibited highly significant differences ( F (7, 16) = 127.2703, p < 0.0001, η 2 = 0.9824; Table 3b).

Two-port ECTR demonstrated an exceptionally large and highly significant effect (SMD = −4.47, 95% CI: −5.67 to −3.26; p < 0.0001), suggesting a profound reduction in symptom severity.

We found a highly significant correlation between age and HNK-1 antigen expression (r = 0.78, P < 0.0001).

Results: Statistically extremely significant ( P < 0.0001) results were found in menstrual irregularities, obesity, and body mass index.

The contrasting behaviour of these two bacterial groups was supported by a highly significant negative relationship ( r 2 = 0.52; P < 0.0001), when data from all treatments were pooled.

A one-way ANOVA test conducted across all transformer-based models yielded a highly significant result (F = 163, p < 0.0001), clearly indicating that model performance in terms of accuracy was not uniform.

The percentage of positive ewes in the provinces varied from 21.3% to 50.1%, with highly significant differences (p < 0.0001) ( Table 1 ).

There was a highly significant correlation between resected liver volumes calculated with ImageJ and the actual measured weights of the resection specimens (Fig. 3 ) ( r 2 = 0.98, p < 0.0001).

The lactation number was highly significant ( p < 0.0001) when comparing LCS groups, as well as the age of the animals ( p < 0.0001).

Unsurprisingly, participants in the 10-h variation slept for longer (7 h 6 min, SD = 38 min) than those in the 6-h variation (4 h 45 min, SD = 28 min), a difference which a two-tailed t test showed was highly significant, t (47) = 14.66, p < .0001, Cohen’s d = 4.34.

The differences in frequencies were highly significant (P<0.0001).

Copulsatility of the GH and GHRH hormone series was highly significant in both patients ( P < 0.0001).

There was a highly significant negative correlation between the changes in PINP and BMD in lumbar spine and femoral neck from baseline to 12 months in all patients (r(s) = -0.68, P < 0.0001, and -0.45, P < 0.0001, respectively), and in pre- and post-menopausal patients separately.

Among the outliers detected by coalescent simulations assuming a neutral island model, five were highly significant ( P <0.0001; Table 3 ).

Statistical analysis using two-way ANOVA with Bonferroni post-test on a pairwise comparison of the profile of the unfertilized oocyte with mRNA profiles collected at different time points after fertilization revealed that the correlation between segment and mRNA level is extremely significant ( P < 0.0001), but that there is no effect of fertilization and time following fertilization ( P ≈ 1).

The IL6 gene was downregulated after treatment with Fuco (20 μg/mL) ( p ≤ 0.0001) while CXCR4 showed a trend of being downregulated after 6 h of treatment with Sm ( p ≤ 0.0001). 3.9.

For the bivariate associations (controlling for clustering within state) all the associations (tested using design based F-statistic) were highly significant (P < 0.0001) except ownership (public versus private) and region.

For the MGL-expressing HEK293-cells, we observed a highly significant (P<0.0001) specificity for GalNAc-BSA ( Figure 1D ).

In Group 4 one patient died from peritonitis while in CR, one from complications of paraplegia while in relapse, one from multiple system failure with minimal hepatic HD and one patient who died at home while in relapse. Excluding the patients above re-analysis of survival still showed a highly significant trend (P<0.0001) for atopic strata.

The data analysis revealed an extremely significant main effect of drug treatment (F [ 3 , 8 ] = 71451, P < 0.0001), accounting for 91.61% of the total variance, indicating it served as the core determinant of the dependent variable.

Thus, as on Day 0, there was a highly significant (p < .0001) effect of time of day on each day (1–11) with elevated levels occurring at the same ZT times as on pre-shift Day 0.

The commonest manifes- tation on all 3 regimens was thrombo- cytopenia and the difference between the B patients and each of the other 2 series was highly significant (P < 0 0001) for each of the 4 comparisons.

Among neonates with AKI, when examining LOH as it relates to GA, we detected a significant trend: as gestational age increases, LOH decreases ( p < 0.0001; Fig. 2 ).

For cases involving a central DSB node (Experimental Section), we observed an increasing trend in DSB probability from the single‐pattern to the multiple‐pattern category (p < 0.0001, Proportion test, Figure 4B ).