Barely Significant

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highly significantP <0.00010.0× alphaqualifiedgold
The second validation step performed by MS-qPCR on core biopsies from 131, 59 and 36 patients with histologically diagnosed PCa, BPH and high-grade PIN, respectively, showed highly significant differences in the methylation status of the APC, TACC2, RARB, DGKZ, C5orf4 and HES5 regions between BPH and PCa ( P <0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
Results White-squid coloration changing according to substrate Our selected mathematical model revealed a highly significant interaction between the fixed effect of substrate (Fig. 3 ) and all the measured RGB color channel values (p < 0.0001) on the head that appear all highly positively correlated with each other and with the mantle (r > 0.94, p < 0.0001; Supplementary Table 1 ) and matching the destination substrate (Fig. 4 ).
highly significantp < 0.00010.0× alphaqualifiedgold
However, the maximum seasonal concentrations differed significantly between the sites (Kruskal‒Wallis p < 0.0001) and a highly significant latitudinal trend of increasing maximum vitamin D 3 at more southern sites was observed (Mann–Kendall trend test p < 0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
The post-hoc Dunn’s test showed highly significant differences between the NV group and the vaccinated animals: SC (mean rank difference = −98.67, p < 0.0001) and ID (mean rank difference = −153.0, p < 0.0001); as well as significant differences between SC and ID (mean rank difference = −54.30, p = 0.0002).