Importantly, a diagnosis of non-Hodgkin lymphoma (NHL) was associated with a highly significant reduction in the risk of EBV reactivation (HR 0.10, CI 0.03–0.33; P =0.0001).
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Even with this drawback, the frequency of heterozygosis and T-alleles was very high and extremely significant when compared with the Ecuadorian control population (P = 0.0001).
Statistical analysis using Mann Whitney test showed that the differences between control and treated groups were highly significant with P value <0.0001 in all cases ( Figure 6 ).
Results A highly significant difference ( p < 0.0001) was observed, indicating that miR-21 expression was higher in CML patients compared to the controls. miR-302 levels were lower in CML patients.
In addition, we discarded SNPs with a minor allele frequency (MAF) <0.1% over the entire data set or with a highly significant departure of individual genotype frequencies from Hardy-Weinberg equilibrium expectations ( P < 10 − 4 ) in at least one population.
There was a highly significant association between the increased use of elastin staining and a perceived increase in VI detection ( p < 0.0001).
All intergroup differences were highly significant ( P = 0.0001; pairwise comparisons P < 0.001).
Only 10 of 68 species were found on both sides of this divide, and ANOSIM showed that this grouping was highly significant (ANOSIM; R = 0.97, p = 0.0001), with the shallower features more similar to each other (ANOSIM; R = 0.43, p = 0.01) than the deeper features were (ANOSIM; R = 0.87, p = 0.1).
A Permanova analysis confirms that there were highly significant differences in the multivariate CHC profiles across the different treatment groups ( F = 37.76, p < 0.0001).
elegans lineage remains highly significant under the new classification ( P <0.0001, compared with 10,000 random lineages with the same lineage tree structure; Fig.
There was a highly significant correlation ( p < 0.0001, correlation coefficient = 0.62) between the two scores.
In each of the three analyses, there was a negative, highly significant correlation between salmon stock development and watermill development (Period 1260–1940: declining stocks for periods without data: r = −0.813 and P < 0.0001; Period 1260–1940: constant stocks for periods without data: r = −0.828 and P < 0.0001; Period 1550–1940: declining stocks for periods without data: r = −0.903 and P < 0.0001).
The Tau2 value, which was barely significant at 0.0927 (95% CI: 0.0229-1.2682), and the Q statistic (Q = 67.50, df = 3, p < 0.0001) further confirmed significant heterogeneity.
Highly significant differences in PH among environments were also detected at all measuring stages in the combined analysis over all 10 three-factor combination environments ( P <0.0001) ( Supplementary Table S3 ), indicating that the ontogeny of PH was influenced by environment.
The P values remained highly significant for NRS ( P <0.0001), VAS ( P <0.0001), BPI-MSF ( P = 0.001), and PDQ ( P = 0.02), while the P values for ≥30% pain reduction ( P = 0.27) and ≥50% pain reduction ( P = 0.02) were also consistent with the primary analyses.
Assessment of total GIPR protein levels in both males and female mice reflected the mRNA findings and depicted a highly significant decline in expression from P7 to P21 ( Fig 2H and 2K , males p<0.0001, females p<0.0001). 2.5 Correlations of protein expression with glucose levels and body weight To determine a potential role or link between receptor expression in the hypothalamus and functions in physiology in development, we analyzed correlations between postnatal blood glucose and body weight in males and females combined.
We observed a highly significant decrease in global viral mRNA levels from proviruses formed by the acetylation deficient QA mutant IN (20-fold, p<0.0001).
We found highly significant evidence that polytrauma patients have more than twice as many days off work (representing an increase of 120 % of the average days of work absence; p < 0.0001) compared with non-polytrauma patients.
Supplementation with EGb did not affect the UA level, although in both the placebo (PLA) and EGb-supplemented groups, the exercise test induced marked increases in UA levels at 1 h of recovery compared to the respective resting values, as reflected by the highly significant time-effect (F = 36.77, p < 0.0001).
While no significant association was observed between ICANS severity and PFS, a direct and highly significant correlation between ICANS grade and OS was seen ( P < 0001, Fig. 1 C, D).
Overall allelic results There were large and highly significant differences in overall allelic distributions between PM and controls for the HLA-DRB1 and DQA1 loci (Table 2 ; p = 0.0001).
For all outlet types, deprivation is a highly significant ( p < 0.0001) predictor of both baseline outlet density and of changes in density over time.
Within group analysis, difference was statistically highly significant ( P <0.0001) in septic AKI but not in septic non-AKI group ( P <0.01).
The scraper inclination angle (X2) exhibited a highly significant main effect (F = 518.11, p < 0.0001), and its quadratic term (X22) was also highly significant (F = 833.74, p < 0.0001), demonstrating that scraper inclination had a pronounced influence on the application rate.
1a , the AKI peptide marker model enabled prediction of AKI with an AUC value of 0.81 and a range within the 95 % confidence interval (CI) from 0.72 to 0.88, which is highly significant ( p < 0.0001).