Excerpts

Chi-squared tests demonstrated that all differences between the observed overlap, and the overlap expected by chance were highly significant ( P < 0.0001).

The fit of the best model to the data was highly significant (Hosmer–Lemeshow χ 2 = 38.17, P < 0.0001).

solanacearum in the rhizosphere soil showed a trend of increased firstly and then decreased with the increase of soil pH (R 2 = 0.5569, P < 0.0001, Fig. 1A ).

Moreover, the quadratic effects of all parameters are significant were highly significant (p < 0.0001).

We found a highly significant difference, with a p-value<0.0001, showing that the signal obtained on spermatozoa expressing the tagged protein is highly specific.

This implied that the linear as well as quadratic effects of all four factors were highly significant ( p < 0.0001) at the 5% significance level.

A highly significant association of bevacizumab use and OS was found after adjusting for covariates (HR = 0.518, 95% CI: 0.374–0.717; p < 0.0001).

This difference is highly significant statistically (p < .0001).

Comparing the survival rates of patients with different histopathological tumor gradings showed a highly significant difference ( p < 0.0001) ( Figure 2 ).

With regard to CD, Faecal BAFF and calprotectin demonstrated highly significant correlation with SES-CD (Spearman’s rank correlation coefficient r = 0.579, p < 0.0001; r = 0.518, p = 0.003, respectively), as shown in Fig. 3A and B .

Microscopic analysis revealed weak positive staining in control tissues versus intensely strong positivity in tumour tissues ( Figure 4A ), with highly significant intergroup differences (p < 0.0001; Figure 4B ).

Highly significant difference were also found between the scores of four education groups (p = 0.0001).

Among the 12 loci associated with MG in the European meta GWAS, we identified nominally significant associations with same directional effects in the CTLA4 at 2q33 (rs231779, OR = 1.17, P = 1.0 × 10 −4 ), FAM76B at chromosome 11q21 (rs4409785, OR = 1.17, P = 0.030), and TNFRSF11A regions at 18q21 (rs7239261, OR = 1.14, P = 1.3 × 10 −3 ) in Japanese (Supplementary Table 2 ).

As presented in Table 7 , the ANOVA results indicate that the factors of models A, B, C, D, AC, BC, BD, CD, A 2 , B 2 , and C 2 are D 2 < 0.05 (at the 95% confidence level, p < 0.05 was considered statistically significant and p < 0.0001 was considered statistically highly significant) [ 14 , 20 , 21 ], indicating that the effects of the nitric acid concentration, leaching temperature, liquid–solid ratio, total pressure, as well as the interactions between these factors and their squared effects on the vanadium leaching efficiency were significant.

From a quantitative standpoint, the ANOVA test showed a highly significant difference among groups for the overall scores (F = 19.14, p < 0.0001).

The model was highly significant, F(4, 47) = 68.83, p < 0.0001, explaining 84.2% of the adjusted variance in QoL (adjusted R 2 = 0.842).

7 A), a remarkable and highly significant increase in NfL levels was observed in the PTX group ( P < 0.0001) and this increase persisted after 2 weeks of follow-up (Fig. 7 B) and until the end of the follow-up period (Fig. 7 C) ( P < 0.0001 and P < 0.05, respectively). 3.7.2.

3 ], with a highly significant interspecific contrast (estimate=21.2×10 −4 , P <0.0001).

Within group follow-up comparisons revealed that the LPC was highly significant in the CN group [ t (33) = 5.2, p < 0.0001], but of borderline significance in the a-MCI patients [ t (23) = 2.1, p = 0.05].

Joinpoint regression analysis also showed a decreasing trend in prevalence according to patient age (APC = -16.2; p<0.0001) ( Supplementary Figure S1 ).

Kinesiophobia, as measured by the Tampa Scale score, demonstrated a decreasing trend with a significant difference ( P < 0.0001*).

, 2015 ), analyses of LD blocks surrounding each highly significant (−log 10 P >4.0) SNP, and curation of a list of candidate genes contained within these blocks (Supplementary Table S3).

However, the effects of the main independent variables were highly significant among treatments (χ 2 = 3312.6, df = 3, P < 0.0001) and the duration of exposure to the fungus (χ 2 = 376.4, df = 4, P < 0.01).

Our analysis revealed a total of 447 significant SNPs across the pearl millet genome associated with primary root growth from which, 109 SNPs were found highly significant with at least two other methods for association analysis at p-value <10 −4 ( Supplementary file 1 , Table S2).

The final model was highly significant (p value <0.0001).