Excerpts

There was an increasing trend in proportions of patients with hypertension as age increased, ranging from about 22% to 48% (p<0.0001) among adults aged 18 years and older.

All four models were highly significant ( p < 0.0001) with non-significant lack-of-fit tests ( p > 0.05), indicating adequate model fit.

When compared with the clot lysis percentage obtained through SK and water, an extremely significant (p value < 0.0001) thrombolytic activity was observed after treating the clots with C. suffruticosa, L. indica and L. aspera extracts.

Finally, Kaplan–Meier survival analysis supported these findings, showing a clear trend of decreasing long-term mortality with increasing HALP scores ( P < .0001) (Fig. 5 ). 4.

DFA on CON versus ADD groups utilizing all factors was highly significant ( p ≤0.0001).

The reduction in EASI scores was statistically significant as early as week 2 ( P = 0.0003), with a highly significant improvement noted by week 12 ( P < 0.0001) [ Figure 1a ].

Highly significant hyperinsulinemia ( p < 0.0001) was noted in diabetics.

The log-rank test showed a highly significant difference in the risk of developing BE between the groups (chi-square (χ2) = 748.93, p < 0.0001), indicating that the timing of disease onset differed greatly.

* p < 0.05, significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; **** p < 0.0001, extremely significant; n.s., not significant.

A quantitative analysis on day seven revealed highly significant differences in the number, size and roundness of the spheroids generated by D5 cells compared to control NIH3T3 cells ( p < 0.0001) (Fig. 3 b).

P ‐value was reported as * p < 0.05 considered statistically significant, ** p < 0.01 considered highly significant, and *** p < 0.0001 very highly significant.

A Spearman's correlation applied to this collapsed data confirmed a highly significant negative relationship (rho = −0.1131, p < .0001).

For LPC, the model's p ‐value was less than 0.0001, indicating a highly significant relationship between the response and the variables ( p < 0.0001).

At the protein level, treatment with pLECs-CM led to a highly significant increase in IL-6 concentration in the cell culture supernatants of both the LFC and AN-LFC (p < 0.0001).

The Wilcoxon test determined there are highly significant differences in SHAPE reactivity between groups for both SLA and SLA′ ( P < 0.0001 for SLA; P < 0.05 for SLA).

All the models were found to be highly significant ( p < 0.0001) as indicated by the cross-validated analysis of variance (ANOVA) diagnostic on the residuals of the regression between cross-validated scores of the predictive O-PLS component and the response in terms of the antioxidant activities.

In contrast, spheroids in the NAFLD group featured highly significant increases in expression of G6PC (6.2‐fold; P < .0001), PCK1 (6.1‐fold; P < .0001), and FASN (13.3‐fold; P < .0001).

Notably, the difference in the EC50 values of both TNBC cell lines, when compared to EC50 values of MCF-10 cells, was highly significant (p < 0.0001).

There were highly significant differences ( p < 0.0001) from the Swiss population in patients from Albania, Bosnia and Herzegovina, and Turkey and significant differences ( p < 0.05) in patients from Bulgaria, Greece, Hungary, and Serbia. 3.3.

The preference for reachable locations was highly significant ( χ 2 test, two nearest LEDs against the three farthest ones, P<0.0001).

General combining ability (GCA) and specific combining ability (SCA) effects were highly significant ( P < 0.0001) for all traits.

Our analyses identified the following variables as highly significant: “mean age,” “number of age groups”, and “data reporting quality” (all p < 0.0001). “Setting,” “disease classification,” and “number of diseases in the classification” were significant (0.01 < p ≤ 0.03), and “data collection period” and “data source” were non-significant.

We found a highly significant elevation in QTd among patients with AWMI compared to other MI types (98.96 ± 2.95 ms vs. 85.08 ± 17.02 ms; p < 0.0001)​.

For pTau181, we observed highly significant effect modification by amyloid status (interaction β = 0.65, p < 0.0001).

The measure of population differentiation, F ST , among the subgroups was 0.15 highly significant at P < 0.0001.