Excerpts

When the repeat number added to the expanded allele in each organ from multiple animals was averaged, the effect of the loss of one or both Mlh3 alleles was found to be highly significant for all organs ( Fig 1B ; p < 0.0001).

Quantitation of total tube length showed a highly significant and robust increase above that of controls going from 1.46 ± 0.5 mm in untreated cells to 5.46 ± 1.4 mm in Dsi2‐treated cells ( P < 0.0001; Figure 3 A), representing nearly a three fold increase.

The overall F-test from ANODIS was highly significant (P < 0.0001, Table 2 ).

Regarding the HO-1d mRNA expression, a highly significant increase ( p < 0.0001) was observed in the liver samples of the old group compared to both the young and the treated animals ( Figure 1 c), while at the pulmonary level, this rise was not significant.

Tumor-free samples and tumor-bearing samples showed clearly significantly different values ( p < 0.0001 each) for all 3 parameters (weight, tracer uptake, SUL).

CD8 and Foxp3 expression also demonstrated a highly significant positive correlation (R 2 =0.27; P<0.0001).

This linear regression had a high fraction of variance explained by the model, R 2 = 0.86, with all points falling within or very close to the 95% confidence intervals (Figure 1C ), and a highly significant p-value of P < 10 −4 based on a permutation test ( 48 ).

At the end of the study, 231/435 (53%) study children completed their vaccination schedule at the fifth contact; 158/256 (62%) were from the intervention group compared to 73/179 (41%) from the control group, a highly significant difference (P=0.0001).

* p < 0.05, significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; **** p < 0.0001, extremely significant; n.s., not significant.

3 , are highly significant ( P < 0.0001 by χ 2 analysis).

Experiment 2: Yearly δ 15 N Monitoring of Bh Genotypes in the Field (Field Trial La Libertad, Colombia) The overall year effect showed an obvious trend of decreasing plant δ 15 N over the experimental seasons ( p < 0.0001) ( Figure 2 ).

We also detected an extremely significant correlation between N-glycan multiplicity and N-glycopeptide levels ( Figure 4B , Mann-Whitney test, p-value<0.0001).

The effects on tumor growth between the experimental groups were highly significant: shRNA ctrl versus shRNA UNG ( P < 0.0001), shRNA ctrl plus FdU treatment versus shRNA UNG ( P = 0.003), and shRNA ctrl plus FdU versus shRNA UNG plus FdU ( P = 0.003).

This difference was highly significant compared to all other cancer types and defined as a bona fide hotspot for CLL ( p < 0.0001, chi-square test).

There were highly significant effects of three of the four individual variables on epitope-specific endpoint titers (p<0.0001); the only individual variable not having a significant effect on antigen endpoints was the geographic origin of the sera (p = 0.0709).

Relationship of thiamine, mortality and body size with fatty acids In the M74 year (1998), YSFM among the offspring of all female salmon had a highly significant negative correlation with the concentrations of THIAM ( r = − 0.811, P < 0.0001) and TotTHIAM ( r = − 0.805, P < 0.0001) in unfertilized eggs and also a correlation with the TMP ( r = − 0.539, P = 0.012), but not with the TPP concentration ( r = − 0.283, P = 0.214).

A one-way ANOVA revealed a highly significant effect of formulation on swelling (S w ) (F(7, 792) ≈ 43,176, p < 0.0001), with a very large effect size (η2 ≈ 0.997).

The results showed that severe/critical patients exhibited significantly higher plasma antigen concentrations compared to those in the mild and moderate groups, with a highly significant statistical difference ( p < 0.0001).

Results Kaplan­Meier analysis showed a highly significant difference in OS between the CMR and N-CMR groups (log-rank test p < 0.0001).

According to the findings, the mean number of promastigotes showed highly significant differences in different concentrations of crocin ( P ≤0.0001).

Age is also highly significant (younger p < 0.0001 in univariate analysis), as is the prevalence of socioeconomic disadvantage in the local area where respondents live (less disadvantage p = 0.0006 in univariate analysis), but both become non-significant in multivariate analysis, i.e. when analysed in the context of the other independent variables.

For example, Fig 5 shows one example of a highly significant relationship between the date and phi (β = 1.779, p<0.0001).

There was a highly significant positive relationship between year and the proportion of investments made as easements measured both in acres and in dollars ( Fig. 1 ; r 2 = 0.64, p<0.0001; r 2 = 0.54, p<0.0001, respectively).

Results A paired t -test revealed a highly significant reduction in the gingival, plaque, and oral hygiene index scores of the manual and powered groups at the first, second, and sixth weeks ( P -value < 0.0001).

Oregano Oil Significantly Reduced Bacterial Burden in Burn Wounds Infected With USA300 As shown in Figure 5A , an average reduction in bacterial luminescence of 2.9 log 10 was attained when the infected wounds were treated with oregano oil at 5 mg/ml for 40 min, which was highly significant compared to only 0.4 log 10 decline of the bioluminescence in the absence of oregano oil during the same period ( P < 0.0001; Figure 5A ).