TNFR1 expression significantly increased in all HIFU-treated Hep3B cells at both 24 and 72 h ( p < 0.0001) as compared to control, and there was also a highly significant difference in the expression between standalone HIFU and ethanol + HIFU treatment groups ( p < 0.0001).
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However, in direct sunlight the background correction applied ceases to function and two-way ANOVA and post-hoc multiple comparisons were highly significant ( p < 0.0001) for background illumination and direct sunlight, respectively ( Table 5 ).
As expected, treatment with cisplatin-induced a highly significant reduction of tumor volume ( p < 0.0001).
The evaluation of the diagnosis showed A highly significant tendency (P < 0.0001 *) to: Gartland I Conservative conduct 87.2% and surgical Conduct-Gartland III 74.2% ( Table 2 ).
Overall, performing GO analysis using DAVID revealed a highly significant enrichment (p < 0.0001) of Biological Process and Cellular Component GO terms related to synaptic function in our gene lists ( Fig. 2 C–F).
We found a highly significant correlation between FCP levels and CDEIS scores (rho = 0.913, P -value < 0.0001, Fig. 1 ).
A highly significant correlation was measured between the presence of a herniation pit and the occurrence of a femoral bump ( P < 0.0001).
At the same time, higher LGR4 positivity was observed in the normal mucosa than in the tumour tissue, with a highly significant difference (93% and 36%, P<0.0001).
The Jonckheere–Terpstra test revealed a significant trend in the false alarm rate over the hallucination groups ( p < 0.0001) ordered in time from never to the past week.
There was indeed a highly significant ( p < 0.0001) positive correlation in the expression of the two genes ( r : 0.60, Spearman test).
Likewise, BEAF + and CP/CH + boundaries on chrX show a highly significant difference in insulation between males and females (Wilcoxon test p -value < 10 −4 ) (Fig. 4e and Supplementary Fig. 8e ).
From a technical point of view, we achieved a highly significant intra‐ (Spearmans ρ = 0.8729, P < 0.0001***) or interobserver (Spearmans ρ = 0.8577, P < 0.0001***) agreement of manual GAM quantification.
Similarly, comparing feature importance between all pairs of the networks presented here (trained to predict expert scores, stroke versus control, stroke size, movement element impairments) also resulted in highly significant correlations (all p < 0.0001; average r = 0.61 ± 0.05 SEM).
A secondary analysis for risk score categories expressed a highly significant detrimental effect on OS and RFS for higher RS ( P < 0.0001) as in Fig. 2 .
A total of 210/337 genes demonstrated negative correlation coefficients with all metallothioneins (F, G, H, M and X), giving a highly significant P value ( P <0.0001).
Pathway analyses conducted on nominally significant targets showed that genes associated with BD and BMI were enriched for the Neuronal cell body Gene Ontology (GO) term ( p = 1.0E−04; false discovery rate (FDR) = 0.025) and different pathways, including the Signaling by Hedgehog pathway ( p = 4.8E−05, FDR = 0.02), while genes associated with BD and T2D showed no specific enrichment.
The difference between the crop communities was highly significant when considering only those isolates derived from MRS media (Chi-sq = 65.9, P<0.0001).
Chi square values for the independence between genotypes of RM136 and days to heading (early and late heading divided by the dotted line in Figure 1 ) were 26.880, 81.073, and 86.693 for Jpn1, Jpn2, and W1297, respectively, all highly significant ( P < 0.0001).
Firstly, the gesture-only conditions (blurred, pointing, give-me gestures) were statistically investigated in a 2-way ANOVA (Time window × Gesture type) calculated across the three time windows, which revealed a highly significant interaction (F(4, 96) = 8.47, ε = 0.66, p = 0.0001, η p 2 = 0.26).
Mortality analysis ( Figure 2 ) Kaplan-Meier analysis showed a significantly lower all-cause mortality in the HIF group compared to the ESA group, with a highly significant log-rank test ( p < 0.0001), indicating improved survival among HIF users.
In the sagittal plane, displacement was highly significant ( Wald p values < 0.0001) in both patients and volunteers, in either half of depolarization (Table S16 ).
lar region, maximum temperature in the ocular region, standard deviation of temperature in the digital flexor tendons of the hind limb, standard deviation of temperature in the tarsus region, maximum temperature in the thorax, and average temperature in the coronary region of the thoracic limb made highly significant contributions ( p < 0.0001) to the discriminant functions when qualitative gait evaluation levels were the clustering criteria.
A highly significant negative correlation between RUNX3 and vimentin protein was observed in these gastric cancer samples ( P < 0.0001; Fig. 8 C).
Likewise, there was a highly significant difference in dry biomass at all tested separation distances (p-value<0.0001) ( Figure 5C ).
Cox multivariate regression model (IS and TNM staging) showed that IS has a highly significant correlation with OS (HR: 2.70; P =0.0001) and DFS (HR: 2.10; P =0.0008) compared to TNM staging system (HR: 1.92; P =0.057 for OS and HR: 1.95; P =0.039 for DFS) ( Table 4 ).