Barely Significant

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highly significantP values <10 −40.0× alphaqualifiedgold
Geographical distribution of folate-mediated one-carbon metabolism pathway alleles and genotypes showing continental variation and intra-population differences in Mexican Mestizos In contrast to the additional four out of the eight variants analyzed, MTRR A66G, MTHFR C677T, A1298AC and MTHFD1 G1958A showed a gradient in the frequency between MEX groups and highly significant differences between AMI and EUR groups ( P values <10 −4 ).
highly significantp < 0.00010.0× alphaqualifiedgold
In the multivariate proportional hazards regression model that included IDLE, TNM staging, tumor grade, and the potential confounding variables (age at surgery, chemotherapy, and radiotherapy received either before or after the surgery) ( Table 2 ), both TNM staging and tumor grade lost statistical association with cancer progression ( p > 0.63) when IDLE was included in the model, while the association of IDLE with progression was highly significant (HR = 5.671, 95% CI = 3.1650–10.1605, p < 0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
The 300 values of the RMS standard deviations (SD) associated with the three channels of the calibrated and non-calibrated orthophoto were compared by means of a paired Wilcoxon test for non-parametric distributions which reported a highly significant difference ( p < 0.0001) between the calibrated and non-calibrated images ( Table 3 ).
highly significantP < 0.00010.0× alphaqualifiedgold
The predicted model developed for catechin (Y 1 ) was as follows: Analysis of variance for predicted models implied that the model was highly significant (F-value 20.13, P < 0.0001) with a good coefficient of determination (R 2 = 0.98).
highly significantP <0.00010.0× alphaqualifiedgold
Lastly, analysis of the relative usage of pAs in 182 genes that displayed significant modulation of at least two alternative pAs ( Supplementary Table S7 ) highlighted a highly significant negative correlation between the abundance of the two APA isoforms for most genes (92.85%; r = –0.8936, P <0.0001, Pearson correlation; Figure 2F ), thus confirming the effect on transcript lengthening induced by HT.
extremely significantp < 0.00010.0× alphaqualified
Figure 4 shows a bar graph of the average A , ε m a x , ε ∞ , τ r of the 4 cell lines and indicates the level of significance: where p > 0.05 is not significant (ns), 0.01 < p < 0.05 is significant (*), 0.001 < p < 0.01 is very significant (**), 0.0001 < p < 0.001 is extremely significant (***) and p < 0.0001 is extremely significant (****), raw values can be found in Table S1 .
a significant trendP < 0.00010.0× alphagold
A more recent analysis for NHANES 2007–2010 data found a significant trend ( P < 0.0001) toward higher HEI 2010 scores for children who consumed 12 oz of juice/d (HEI = 52.3) than those who did not consume juice (HEI = 43.8) ( 40 ) There are reports that argue fruit juice consumption is comparable with consuming sugar-sweetened beverages that contribute to overweight and obesity, particularly among children ( 41 – 43 ).
highly significantp < 0.00010.0× alphaqualifiedgold
The test for residual heterogeneity was highly significant ( p < 0.0001). 4.4.1.2 DBS primary for treating chronic pain (DBS-P) analysis The test of moderators for age as a predictor was not significant F(df1 = 1, df2 = 22) = 1.1608, ( p = 0.29), indicating that age did not significantly moderate the effectiveness of DBS-P for chronic pain The estimated amount of residual heterogeneity (tau^2) was 43.86, indicating considerable heterogeneity among the studies.
highly significantP -value < 0.00010.0× alphaqualifiedgold
No significant differences in the prognostic value are noted between iPET-2 and i-PET-4 with both showing highly significant differences in EFS between the CMR and nCMR patients ( P -value < 0.0001): patients with iPET-2-CMR and iPET-2-nCMR had 3-y-EFS’s of 93.1% and 45.5%, respectively while the respective values for patients with iPET-4-CMR and iPET-4-nCMR were 89.5 and 39.4%.