This is a highly significant enrichment among all significant proteins in the dataset of that independent study (odds ratio 10, P < 0.0001, Fig EV5 B).
Excerpts
The incidence of reaction around the depot was significantly increased in eyes with larger pored particles and there was a significant trend for higher incidence of vitreous reaction with larger pores (10 nm: 0%, 30 nm: 29%, 50 nm: 71%, 100 nm: 100%, p < .0001, Cochran Armitage Trend Test).
The treatment of SKBR3 cells with rising concentrations of IKK-16 resulted in a highly significant decrease in cell viability (5 μM p < 0.0001; 50 μM p < 0.0001).
Survival analysis revealed highly significant differences between high-risk and low-risk groups (p < 0.0001) (Fig. 5 A), with ROC curve values at multiple time points exceeding 0.7 (Fig. 5 D).
The statistical analysis indicates highly significant results (p-value < 0.0001) for the uncontrolled cases.
The KM curves were drawn (as shown in Figure 6C ), and a markedly significant difference of p < 0.0001 was observed between the groups.
Normalized mean expression levels detected by qPCR and RNA-Seq showed a strong correlation, as ascertained by highly significant ( P < 0.0001) Pearson’s coefficient ( r = 0.91; see Supplementary Fig.
Results showed a highly significant difference between h SFs taken up by Pv EVs as opposed to h EVs (unpaired t -test ****p < 0.0001) (Supplementary Fig. 6 ).
As true for PDAC, SST methylation and expression in other gastrointestinal cancers showed highly significant hypermethylation and downregulation of expression ( P < 0.0001; Fig. 4B ).
The highly significant regression model was verified by a low P value ( P < 0.0001), which should be less than 0.05 [ 28 ].
These correlations are slightly reduced with Salmon derived correlations (R2 average 0.6) but remain always highly significant (each p-value < 0.0001).
Although this value was still significantly lower than that of the WT animals (220 ± 15 s, p < 0.01), the difference with untreated affected littermates was highly significant (p < 0.0001).
The results indicate that Group (ASD and the two TD groups) and Task (with and without objects) as main factors, are highly significant: (Group: F [2,75] 72,55 p<.0001; Task F [1,75] 220,52 p<.0001).
The decrease from 16 to 20 years of age (76.22%) to 31 to 35 years of age (60.13%) is statistically highly significant ( p < 0.0001).
1.74 ± 0.04, P < 0.0001), with a clear trend across VAI quartiles showing increasing prevalence of untreated dental caries with higher VAI quartiles ( P < 0.0001), suggesting a potential dose–response relationship between visceral adiposity and dental caries risk.
The difference between the two averages of the peak heart rate was highly significant ( p = 0.0001; Wilcoxon signed-rank test, W = −225, n s/ r = 21, z = −3.9).
The influence of DSCC on the variation in milk components was always highly significant ( p < 0.0001), whereas it was not significant for milk yield and lactose.
Again, seasonality had a highly significant effect on both metrics ( P < 0.0001), while the health status was non-significant ( Table 1 ).
Fig 6A shows the results of a logistic regression show a highly significant ( p < 0.0001) positive correlation between T barrel and the escape probability ε of descended tabanids ( S11 Table ).
The combination of both mucosal MMP-based parameters appeared as a highly significant discriminator (LR 20.30, P <0.0001) for subdivision of patients into good, intermediate and poor survivors as shown in Figure 1D .
Anatomical parameters: In the experimental group, the measurements of KGB, DAP and DBP were all reduced and DCM and DTM were all increased and observed to be symmetrical for both the legs at week 12 and were highly significant (p<0.0001) when compared to the control group ( tables 2A - 3B ) But they were not significant and remained as asymmetrical in the control group at week 12 when compared to week 0 ( tables 2A - 3B ).
On comparison of the proportion of the patients requiring only the ST graft, the p value came out to be highly significant ( p < 0.0001), showing that the ST tendon alone is enough when using the weave technique to achieve the required graft diameter.
No significant difference was observed in age and gender between the two groups ( p > 0.05 and p = 0.15, respectively). Among the RBC indices, the RDW level was higher and was highly significant in the PD group than in the control group (16.56 ± 2.32 vs. 15.12 ± 2.43; p < 0.0001).
Thus, we calculated that the likelihood of 15 consecutive successes (= correct identification of slides) was (l/2) 15 = 6.1 × 10 -5 , which means that the result is highly significant (p < 0.0001) and unlikely to consequence of chance.
It was shows that: (i) The PLE-III fitted to all 3 datasets extremely significant with p -value < 0.0001, and the standard errors of the model parameters were close to zero.