Excerpts

Among infected fish we observed a significant reduction in microbial richness (Chao1, P = 0.0136), raised diversity (Shannon, P < 7.86e-06) as well as highly significant destabilisation of microbial community composition (Pairwise Unifrac, beta-diversity, P < 1.86e-05; P = 0.0132) by comparison to controls.

The 3′ UTR of HCOI00821400 showed a small (10.5%) but highly significant reduction ( p = 1.9E-5) in expression in the presence of the forward hco-miR-9551 , while there was no difference in expression for the 3′ UTRs of HCOI00084600 and HCOI01910900 when cells were transfected with the forward or reverse hco-miR-9551 .The mean of three experiments comparing expression in the presence of the forward hco-miR-9551 relative to the reverse is shown in Figure 7 .

3C ), we observed that palmitoleate (16:1), a major constituent of the glycerides in human adipose tissue that has been associated with increased insulin sensitivity ( 31 ), exhibited a highly significant change with CR (3.61-fold, P = 1.9 × 10 −5 ).

The top result did not reach statistical significance (Bonferroni threshold for number of genes, p-value < 1.93 × 10 −5 ) was with increased predicted expression of ETS variant 4 ( ETV4 ; chromosome 17; p-value = 0.0015).

This is a highly significant enrichment (p-value = 1.98e-5, hypergeometric test).

Another haplotype located just 5′ to MSRA showed nearly significant over-transmission to individuals with MI, indicating that it conferred risk for MI (59 informative families, raw P = 1.99×10 −5 ; Bonferroni P = 0.057).

We found that this relation is quite significant (MIC = 0.54, p value ≤ 2e−5; see “ Analysis ” under the “ Methods ” section).

Again, a highly significant (p = 2 × 10 −5 ) overlap was observed in kidney cancer.

As a result, a significant difference between the prisms with and without cyanobacteria was detected (Figure 2) for bending tensile strength (t = 2.9717; p = 0.0180) and a highly significant difference for compressive strength (t = 5.75; p = 0.00002).

All model terms were highly significant ( p < 2e − 5), with acidic group count (nAcid) displaying the most significant effect ( p = 3.2e − 7) (Fig. 2 e), consistent with the group-wise investigation of LMs (Fig. 2 a).

For the U-87 MG glioblastoma cell line, on which the present study was focused and for which correspondingly more experiments were performed, the enhancement was statistically highly significant ( p = 2 × 10 −5 ).

The log-rank test for a difference in the CIF for GFNA between recipient age <50 and ≥50 years was highly significant, yielding p = 0.00002.

In contrast the log-SED index had a highly significant association with the MD values ( P = 0.00002).

To address the potential physiological significance of neutrophil count normalization by hRabMab1+gem/PTX in the PaCa-44 model, we performed correlation analysis between circulating neutrophil counts and tumor volumes across all 4 cohorts; a highly significant positive correlation between neutrophil counts and tumor volumes was identified (R = 0.628, p = 0.00002), mirroring findings reported in human patients [ 22 ].

Based on the observed data, a negative trend of four species lost per census (per 5 years) was observed ( figure 4 d ; average p = 2 × 10 −5 from bootstrap least-squares linear regression).

Further, the differences between them were highly significant (Mann-Whitney U -test, P = 2 × 10 −5 ).

The difference between the cumulative growth in the number of PVCs in the control and riluzole groups was highly significant, at p<0.00002.

However, the overall difference for these three genes is highly significant (Chi-squared test, P = 2e-5).

As expected, we see highly significant enrichment of terms related to influenza (Fig. 7 a) including Transport of Virus ( p = 2.0 × 10 −5 ), Influenza Life Cycle ( p = 5.8 × 10 −4 ), and Influenza Infection ( p = 7.7 × 10 −4 ).

This analysis indicates that the 33 genes identified in our study represent a highly significant level of overlap ( p < 0.00002).

By 24 hours, the difference was highly significant ( P = 0.00002), with 30% and 40% of patients on nalbuphine experiencing no or mild pain compared with 15% and 25% of patients in the morphine group, respectively.

Indeed, used alone, CD9 based sorting yielded a highly significant, 14-fold enrichment in CD140a + /PDGFRα + cells relative to their unsorted dissociates (t-test, p=0.00002).

Interestingly, the rs3813065 SNP was associated with a highly significant difference in the expression of endoplasmic reticulum aminopeptidase 2 ( ERAP2 ) in the HapMap cell lines derived from the African Yoruba population ( P = 2 × 10 −5 ).

Results Correlation analysis between CNV values obtained with the two methods was slightly significant ( R = 0.413, p = 0.00002), because of the wider data dispersion in qPCR compared with ddPCR.

When the entire sample was evaluated together, the facial asymmetry scores of the scoliosis group were significantly higher than those of the non-scoliosis group, and this difference was statistically highly significant (U = 1848.5; p = 0.00002).