Excerpts

We also observed a highly significant difference in allele frequency between the Benin and Yoruba samples (HapMap Project) for the SNP rs3130315 (p = 2 × 10 -5 ) and between the Mongolian and Han Chinese samples (HapMap project) for two SNPs: rs9562080 (p = 0.047) and rs4116821 (7.36 × 10 -11 ).

Further, the differences between them were highly significant (Mann-Whitney U -test, P = 2 × 10 −5 ).

As expected, we see highly significant enrichment of terms related to influenza (Fig. 7 a) including Transport of Virus ( p = 2.0 × 10 −5 ), Influenza Life Cycle ( p = 5.8 × 10 −4 ), and Influenza Infection ( p = 7.7 × 10 −4 ).

This analysis indicates that the 33 genes identified in our study represent a highly significant level of overlap ( p < 0.00002).

Since our GWAS hits are of marginal significance, the false discovery rate within this range of P -values is high (for example, at P -value≤2e−05, the FDR is 0.66).

The increase in predictive power is highly significant ( p < 2 × 10 −5 ; paired Wilcoxon test).

We found that this relation is quite significant (MIC = 0.54, p value ≤ 2e−5; see “ Analysis ” under the “ Methods ” section).

Effect of seed treatments with bacterial endophytes on OSR yield, growth and disease incidence under commercial field conditions (Poříčí, Czech Republic) Except for a highly significant (P = 0.00002 and P = 0.00033, respectively) reduction of stress symptoms (red discolouration of leaf margins) by both IP and IG inocula in early spring (March 2017; Table 2 ) none of the seed treatments with bacterial endophytes affected growth, yield and diseases of OSR significantly under commercial field conditions.

Results Correlation analysis between CNV values obtained with the two methods was slightly significant ( R = 0.413, p = 0.00002), because of the wider data dispersion in qPCR compared with ddPCR.

However, the overall difference for these three genes is highly significant (Chi-squared test, P = 2e-5).

In contrast the log-SED index had a highly significant association with the MD values ( P = 0.00002).

Again, a highly significant (p = 2 × 10 −5 ) overlap was observed in kidney cancer.

In 1971, Pauling published a meta-analysis in which he showed that there was highly significant evidence from four placebo-controlled trials that vitamin C is beneficial against the common cold with p = 0.00002 ( 56 ), a conclusion that has since been corroborated in a large series of further randomized trials ( 57 , 58 ).

As a result, chromosomal differentiation between mtDNA subclades across both traits was highly significant (Fisher’s exact test, Chi-Squared > 26.46, d.f. = 4, p < 0.00002), but it was high and significant for A-chromosome number (F ST = 0.763, N = 82, p < 0.00001) and low and not significant for B-chromosome frequencies (F ST = 0.090, N = 41, p = 0.179).

Importantly, we also observed a highly significant inverse correlation with the expression of AR (P = 0.00002) (Figure 1 A).

The observed difference in the monthly prevalence of the DEC was highly significant in the month of March (P = 0.00002) ( Table 3 ).

The number of observed confirmations is highly significant ( P < 2 × 10 −5 , Z -score = 77.2), because no more than 16 matches (1%) were observed in 50,000 simulations that apply a transcription factor's annotations to its shuffled motifs ( Fig. 3D ).

Compared with the CC-Random group ( Appendix A:Supporting Information S2 ), The relative matched frequency (RF) of the BFE-mRNA sequence was more obvious in these two regions, and the difference in RF at the 3’end was highly significant ( t -test, p < 0.00002).

Indeed, used alone, CD9 based sorting yielded a highly significant, 14-fold enrichment in CD140a + /PDGFRα + cells relative to their unsorted dissociates (t-test, p=0.00002).

ID 653 was therefore experimentally regrouped into the viral group, which resulted in a highly significant p-value ( p = 2e -5 ; Fig 7B and 7D ). 3.2.2 Bacterial No statistically significant group differences could be detected for bacterial presence in this investigation.

The difference between the cumulative growth in the number of PVCs in the control and riluzole groups was highly significant, at p<0.00002.

Interestingly, the rs3813065 SNP was associated with a highly significant difference in the expression of endoplasmic reticulum aminopeptidase 2 ( ERAP2 ) in the HapMap cell lines derived from the African Yoruba population ( P = 2 × 10 −5 ).

When the entire sample was evaluated together, the facial asymmetry scores of the scoliosis group were significantly higher than those of the non-scoliosis group, and this difference was statistically highly significant (U = 1848.5; p = 0.00002).

We observed a highly significant positive correlation between MSI/hypermutation frequency and the total number of somatic mutations per cancer after integration by OncoMerge (R = 0.68 and p value = 2.0 × 10 −5 ).

collagen gingivitis hydroxyproline metabolomics obesity It should be noted that regression between obesity measured by waist circumference and gingivitis measured by percent of red sites had a high correlation (r = 0.66) and was highly significant ( P = 0.00002).