Excerpts

The apical recurrence rate was reduced from 52% to 15% (SD 10.7%), which is also highly significant, p < 0.00001, as was the reduction in the posterior compartment recurrences–31% reduced to 10% (SD 10.2%) with p < 0.00001.

All pair-wise comparisons showed highly significant levels of population genetic differentiation (P<10 -5 , Table S2 ).

Of these 27 loci, five loci were identified as either genome-wide significant or suggestive of significance ( p < 1 × 10 −5 ) in a separate, previously published GWAS of one of the five traits. 118 loci were genome-wide significant for neuroticism, with 38 loci not identified in the univariate item-level GWASs ( Supplementary Table 6 ; Figure 1b , Figure 2b ).

The deviation from Hardy-Weinberg equilibrium is highly significant ( P < 10 −5 , Fisher’s Exact Test 40 ) with a complete absence of heterozygotes.

Only highly significant meta-analysis results (p-values <0.00001) were used to select a subset of SNPs – AD-associated genes confirmed by numerous studies [17] .

For example, witnessing violence toward siblings on the MACE showed a highly significant association with DES scores (β = 2.02, t = 4.75 p < 10 -5 ), whereas witnessing interparental violence did not (β = 0.60, t = 1.44, p = 0.15) and experiencing physical abuse had only a marginal association (β = 0.85, t = 1.83, p < 0.07).

Results The values of LV-EDV and LV-ESV measured in 3D-ECHO showed highly significant correlations with CMR (for LV-EDV r = 0.892, p < 0.00001; for LV-ESV r = 0.896, p < 0.00001).

The overall effect was highly significant (Z=4.90, P<0.00001), confirming the effect of supply center management protocols on reducing the incidence of HAIs.

41 , 42 If these studies had been included, there would be a highly significant ( P < 0.00001) association between chemoprophylaxis and postoperative bleeding. 38 Moreover, a 2016 meta-analysis by Pannucci et al 43 found a higher risk of hematomas ( P = 0.02) in anticoagulated plastic surgery patients, in addition to no significant reduction in VTE risk in plastic surgery inpatients with Caprini scores >8.

However, since there are only around 80 confirmed and 120 predicted imprinted loci in total in the human genome, the observation of even just ten of these genes in our study represents a highly significant enrichment ( P < 1 × 10 −5 ; permutation test).

The Wald test and the likelihood ratio test were highly significant (P<0.00001 for both tests and for either model), and the pseudo-R 2 value and Hosmer and Lemeshow test confirmed the goodness-of-fit of both models.

However, the difference was relatively small, and when we eliminated the regions overlapping promoters the differences in the substitution rates estimated for neutrally evolving sequences and lncRNAs remained highly significant (Wilcoxon test, P -value < 10 −5 ).

This was also highly significant ( p <0.00001).

The test for overall effect was highly significant (Z = 5.57, p < 0.00001), indicating a significant association between knowledge scores and experience across all categories.

The overall effect of the combined subgroups (COI and no COI) was also highly significant for patients treated with BEVA ( p < 0.00001).

The fixed-effects model reported a highly significant difference between the buffered and unbuffered solutions in terms of duration of onset of anesthesia (P = 0.00001, MD: −12.38, 95% CI: −17.64 to −7.13; Fig. 5 ). 7.

The overall effect of surgery compared to sham surgery was highly significant (SMD 0.34, 95% CI 0.20 to 0.49; p<0.00001), while heterogeneity was large (I 2 =67%, p<0.00001).

The differences were highly significant in the Z-test ( p < 0.00001) for African American and Latino populations.

Genome-wide significance was the accepted P < 5 × 10 −8 while marginal significance was P < 1 × 10 −5 .

Results Nadi Shodhana Pranayama showed a significant decrease in ART (p = 0.01) and Bhramari Pranayama showed a highly significant decrease in ART (p < 0.00001).

Even after accounting for eye and exam number nested within subjects, MAP accuracy values remained a highly significant predictor of MAIA values, t (1071.9) = 5.03, P < 0.00001.

Figure 7 a shows the relationship between LAI r and LAI-vc e by applying method (ii) with k r obtained by inverting Equation (7), which rendered highly significant statistical analysis ( Table 4 ) as expected ( R 2 = 0.94; b = 0.98; SEE = 0.71; RMSE = 0.15; p < 0.00001).

Based on the two tailed Mann‐Whitney U test, the estimated P values for comparing these aiLUNG‐COVID‐19 vs aiLUNG factors were highly significant at P = .00001.

3.2 Response to ETI therapy initiation Effects of ETI therapy assessed with averaged CFAbd-day2day © responses revealed a highly significant decrease in the median total score ( p = 0.00001).

Future habitat suitability variation Pearson’s correlation coefficients between the habitat suitability maps generated for the different timeframes (2041-2060 and 2061-2080) and future climate scenarios were all higher than 0.999 for the ALP models and between 0.991 and 0.999 for APE; all the correlations were highly significant after Dutilleul's correction for spatial autocorrelation (p < 1×10 −5 ).