Excerpts

Overall, there is a highly significant effect of training week across the balance beam crossing time data [ F (18 , 4914) = 5.1, p < 0.00001].

Highly significant (P < 0.00001) pairwise correlations were observed for 431 out of the 703 possible pairs for the 38 probesets examined in this study.

Neurophysiologic Analysis Not surprisingly, in keeping with prior studies (e.g., 28 , 55 , 57 ), on average, there was a highly significant effect of odorant on both the spatial patterns of different odorants (F [4, 430] = 128.28; P < 0.00001) and the response magnitude (F [4, 437] = 117.26; P < 0.00001).

Within-group comparisons of SI increases from T1 against T2 values yielded highly significant differences for CPP–PCs ( n = 57, 0.23 ± 0.05 bits per spike, mean ± s.e.m.; P = 1 × 10 −5 , T = 4.86, one-sample t -test) and SAL–PCs ( n = 61, 0.26 ± 0.07 bits per spike, mean ± s.e.m.; P = 4.5 × 10 −4 , T = 3.7, one-sample t -test).

2011 ), which is highly significant (permutation P < 1 × 10 −5 ) ( Fig. 3 B).

There is a highly significant correlation of the expression levels of individual ta-TRIM s as determined from EST and from RNA-Seq data (Pearson correlation test, P < 0.00001), confirming that the variation observed among ta-TRIM s is not an artifact of the mapping algorithm or the selected parameters.

This analysis revealed a single highly significant CCA mode that relates functional connectomes to subject measures (r=0.87, P<10 −5 corrected for multiple comparisons across all modes estimated).

There was no significant difference in MM96L when siNF1 was compared with miR-514a, whereas in MM253, particularly at higher drug dosage (10-100nM), the differences between siNF1 and miR-514a, were highly significant ( p < 0.00001) (Figure 5a ), indicating that the mode of BRAFi resistance was different, possibly due to other targeted genes of miR-514a.

Acquisition was fast and highly significant ( F (2,294) = 183.65, P < 0.00001), reaching 80% of conditioned responses at the last acquisition trial ( Fig. 1 A).

The highly significant difference in values ranged between 57 pg/mL ( P < 0.00001), 161 pg/mL ( P < 0.00001), 112 pg/mL ( P < 0.00001), 67 pg/mL ( P < 0.000008), and 226 pg/mL ( P < 0.000005), respectively for IL-1 α , IL-1 β , IL-6, MCP-1, and TNF- α .

However, several nominally significant (p<1.00E-05) variants were identified ( Table 2 ).

When 29 studies containing 4,390 patients who had received radical surgery (I–III) were considered, highly significant heterogeneity was detected ( χ 2 =92.48, P <0.00001; I 2 =70%).

Highly significant inter-study heterogeneity was noted (I 2 = 85%; χ2 p= 0.00001).

The main effect of the post-error was highly significant ( F (1,37) = 204.6; p < 0.00001) indicating that response time increased after errors in a stop trial (Fig. 3a : the difference between the after-error and after-correct trials).

Furthermore, a similar association pattern was observed in SNPs near the MIR4458HG gene (distance ~33 kb) in chromosome 5 with marginal significance ( P -value < 1.0E−05) in all models (Table 2 , Additional File 1 : Table S1).

A linear regression model between vehicle occupants’ death rate and seatbelt noncompliance in our published data was highly significant ( P <.00001) ( Figure 1 ).

The two-sample t-test for comparison of the means was highly significant (t=−16.5, p<0.00001).

The pre- and post-VAS values were compared and statistically highly significant difference ( P < 0.001%) in mean VAS and clinical scores was observed.

The genotype × harvest season interaction was highly significant (Fg × hs = 4.00, p < 0.00001), indicating the presence of clones with distinct yield performance over time ( Figure 1 ).

2010 ) to explore to what extent candidate epistatic modifier genes for the Sema‐5c BG2386 and neur BG2391 alleles identified by our GWA analyses form interactive networks, using as input all candidate modifier genes with nominally significant associations at P < 10 −5 (Table S4 and S5).

Results: A strong and statistically highly significant (r=0.98; p<0.00001) Pearson’s correlation was found between bone age assessed from hand-wrist radiographs using Björk’s method and bone age assessed from cephalometric radiographs using the method by Baccetti et al.

There was a highly significant correlation between both dynamics rates (R = 0.769, p < 0.00001).

For all data sets (cortical CBF, subcortical CBF or RBF; during blood removal or reperfusion), three-parameter logistic regression curves with highly significant correlations for blood flow and MABP could be fitted to the data ( Figure 4 ; correlation coefficients are given in the respective panels; p < 0.00001 for all data sets).

Given the small sample size, nominally significant CpG-smoking associations were defined as having P < 1x10 −5 and were displayed using a ggplot2 boxplot.

There was a highly significant positive correlation between male and female suicide rates in both the 65-74 years (rho=+0.87, P<0.00001) and 75+ years (rho=+0.89, P<0.00001) age-bands.