Barely Significant

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highly significantp < 1E−50.0× alphaqualifiedgold
The power of the TCI to predict the membership of individuals in a particular rsFC group (i.e., squared multiple regression R 2 ) was strong and highly significant for group 1 (R 2 = 52%, F = 79.42, p < 1E−5, RMSE 0.11), group 3 (R 2 = 67%, F = 142.9, p < 1E−5, RMSE = 0.07), group 4 (R 2 = 35%, f = 51.2, p < 1E−5, RMSE 0.17), and group 5 (R 2 = 46%, F = 7 l.9, p < 1E−5, RMSE 0.14).
highly significantP <0.000010.0× alphaqualifiedgold
Therefore, there is a highly significant difference in the expression of functional GABA B receptors on VTA GABA neurons compared to VTA dopamine neurons ( P <0.00001, Fisher exact test), making this property the most reliable pharmacological difference between GABAergic and dopaminergic VTA populations.
highly significantP < 10 −50.0× alphaqualifiedgold
In splenic macrophages from arthritic mice treated with TNFα targeting but not with control siRNA, we found a decrease of intracellular TNFα staining indicating effective silencing ( Figure 6b ).Overall, the effect of treatment on mean fluorescent intensity value is highly significant according to an ANOVA ( F = 17.061, P < 10 −5 ).
highly significantp < 0.000010.0× alphaqualifiedgold
The mean behaviour of these groups of genes in response to heat shock displays a highly significant positive correlation (Pearson r = 0.312, p < 0.00001, Spearman r = 0.314, p < 0.00001; electronic supplementary material, file S2), such that those mRNAs corresponding genes more distant from transcription initiation sites increase in abundance while those close to transcription initiation sites decrease.
highly significantp > 0.000010.0× alphaqualifiedgold
Two other groups that are characterized by significant differences from all the other groups are the populations from the North Caucasus (Dargins, Avars, and Lezgins), the Bashkirs, and the Khakas. The total level of genetic differentiation of the pool consisting of 17 populations turned out to be relatively high ( F st = 0.0267, or 2.67%) and highly significant ( p > 0.00001).