Correlation of CDX2 with clinicopathological parameters CDX2 expression was inversely associated with lymph node metastasis (high CDX2 expression was associated with decreased lymph node metastasis (RR=1.52, 95% CI: 1.29-1.79, P<0.00001) ( Figure 5 ) however, CDX2 expression was significantly higher in poorly differentiated gastric cancers (RR=1.52, 1.52; and significantly higher in well-differentiated and latent gastric cancers marginal significance compared with 95% CI: 1.22-1.87, P<0.00001) ( Figure 6 ) was observed (RR =0.82, 95%).CI =0.67-1.01, P=0.07) ( Figure 8 ).
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Expression of the four genes was correlated with highly significant correlation between PPARG, LPL and CD36 ( r > 0.9; P < 0.00001), and moderately significantly correlation with FABP4 ( r > 0.6, P < 0.001).
6b and 6f ) is highly significant ( p = 10 −5 ).
For WGA-specific antibodies, the p values are listed as p > 0.05 for 25 different tissue antigens and highly significant p values ( p < 0.00001) for 37 antigens.
The combined group demonstrated a substantially larger and highly significant positive effect (SMD = 2.02, 95% CI: 1.83 to 2.21; P < 0.00001).
We observed a highly significant correlation between aggregation and lipophilicity ( p -value < 0.00001) ( Figure 2 A).
Comparison between the groups showed a highly significant difference in anxiety score reduction, with the compliant group demonstrating greater improvement (p<0.00001) Table 2 .
Similarly, when anxiety was assessed using the SAS, CBT demonstrated a stronger and highly significant effect (MD = −6.22; 95% CI −7.63 to −4.80; P < 0.00001), also with no heterogeneity ( I 2 = 0%).
The genotype × harvest season interaction was highly significant (Fg × hs = 4.00, p < 0.00001), indicating the presence of clones with distinct yield performance over time ( Figure 1 ).
Pairwise F ST values with outlier SNPs were all highly significant ( p < 0.00001) and were highest for comparisons involving the conventional plot ( F ST = 0.071 for conventional versus semi-conventional; F ST = 0.070 for conventional versus semi-organic; F ST = 0.049 for semi-conventional versus semi-organic).
These differences are highly significant ( p < 0.00001) whether compared as frequency, average, or normalized by CNV size.
2.8 EWAS of physical activity and functional analyses At the nominally significant threshold (defined as p < 1 × 10 −5 ), we identified 7 CpGs associated with %time spent in MVPA (Figure 3a and Table S4a ), and 12 CpGs associated with MET‐Hours (Figure 3b and Table S4b ).
The highly significant similarity of gene expression from same-host papillomas suggested that germline polymorphisms affect constitutive levels of gene expression in benign tumors ( P < 0.00001 by permutation; see Materials and methods).
This revealed a total of 52 out of 176 neurofeedback runs that achieved high regulation (~30%; median per participant: 2; MAD: 1.7; range: 0–6), which was highly significant according to binomial testing ( P < 0.00001) (Fig. 2C ).
The mean difference found in the forest plot was 3.28, with a confidence interval of 1.92 to 4.65, indicating a strong trend favoring Control, with very strong statistical significance (p<0.00001).
The differences were highly significant in the Z-test ( p < 0.00001) for African American and Latino populations.
A highly significant association (p < 0.00001) was found between the trend of menstrual products used by the participants and their monthly income/capital to maintain their livelihood (Table 2 ).
This difference was highly significant ( P < 0.00001) in favor of endovascular coiling [ Figure 3a ].
In addition, although the acute EtOH response of CE and CS group mice was measured at different stages of the study, on day 3 in CE and day 11 in CS, the genetic correlation was highly significant ( r = 0.92, p < 0.00001).
With the exception of “CSF-Aβ38” and “CSF-Aβ40” all showed strong and highly significant association with markers in the APOE region but no better than suggestive ( P < 1E-05) signals in the remaining genome (see Supplementary Figs. 3 – 7 and Supplementary Tables 7 – 11 ).
As expected from the voxel-wise analysis, all the regions of interest (AI, OP3, OP4, OP8, PIC, PIVC) show highly significant activations in the “Visual + vestibular” > “Visual only” contrast, with FDR adjusted p values < 10 −5 in all cases (Fig. 3 b).
A total of 90 highly significant QTL (245 SNPs; p < 10 −5 ) were identified for salinity-related traits with the strongest associations detected for root Na + content followed by root Na + :K + ( Fig 2A and 2B , respectively).
In fact, both correlations are highly significant (p < 0.00001 for each in Fig 2B ).
Relative to the codon frequency of the native DNA, the Mann-Whitney-Wilcox rank-sum analysis of the optimized CDSs shows that two are non-significantly (n.s.) optimized, four exhibit a p value between 1.4E−03 and 7.7E−04, and three are highly significant with a p < 1E−05 (GenScript, GeneArt, COOL).
As can be clearly seen, there was a highly significant reduction in paw withdrawal latency after the CCI ( P < 10 −5 ; ANOVA).