The strongest structure was among all populations (F ST = 0.098), followed by differentiation among the two ecotypes (F CT = 0.068) and then differentiation among populations within ecotypes (F SC = 0.032), and all were highly significant (p < 10 −5 , Table 5 ).
Excerpts
Concurrently, it establishes with highly significant evidence the definite advantage of aspirin in reducing the risk of minor bleeding (OR = 0.57, p < 0.00001).
Hence, undertaking multiple comparisons the overall global improvement with AOTG remains highly significant ( p < 0.00001), while each of the domains remain significant with two or one sided tests.
The proportion of individual habitats in hunting districts was statistically highly significant (Chi 2 with Yates = 361.92, df = 8, p <0.00001).
Prevalence of SNOCIs who presented with solitary positive anti-HCV IgG antibody in non-viremia patients (34.82%) was highly significant (higher) compared to prevalence of COCIs (3.125%) in negative controls for both IgG antibodies and viremia ( p < 0.00001).
The changes in the right prefrontal Oxy‐Hb had a highly significant positive correlation with the changes in the left prefrontal Oxy‐Hb ( γ = 0.995, P < 0.00001).
Prep1 DR induced a 2-fold increase of highly significant DNA-binding sites (p < 10 −5 ) in P versus C cells before differentiation at day −2, and a further 2-fold increase 4 hours after induction of differentiation (Fig. 4B and Supplementary Fig.
For sedentary individuals, the results show highly significant differences between the four conditions [ χ ( 3 ) 2 = 25.15, p = 0.00001].
2012 )—a highly significant difference ( P < 0.00001, χ 2 test).
The terms for DNA-binding transcription activator activity (RNA polymerase II-specific) and actin binding were highly significant ( p = 1.0 × 10 −5 ), as was microtubule binding ( p = 2.0 × 10 −5 ).
This was found to be statistically highly significant ( P < 0.00001).
graminis cultures were positively correlated with one another and very highly significant ( P = 0.00001) ( Table 2 ).
Interestingly, investigation of intragenic relationships between VastDB AS events reveals that pairs of cassette exons (especially in the case of neighboring exons) and pairs of retained introns within the same gene show highly significant correlation of inclusion or retention levels across samples from each species ( P < 10 −5 , Wilcoxon rank-sum test) ( Supplemental Fig.
The recombination was highly significant with the A/D motif recombinants (p = 10 × 10 −6 ), the C/D motif recombinants (p = 6.5 × 10 −11 ), the B/D motif recombinants (p = 0.03), and the A/E motif recombinants (p = 0.007).
Importantly, this was supported by our data with a highly significant decrease in CSF acetylcholine levels (Figs. 2 , 3 , and Table 3 , 0.36-fold change, p <0.00001).
As expected from the voxel-wise analysis, all the regions of interest (AI, OP3, OP4, OP8, PIC, PIVC) show highly significant activations in the “Visual + vestibular” > “Visual only” contrast, with FDR adjusted p values < 10 −5 in all cases (Fig. 3 b).
This was highly significant with a P = 0.00001.
This difference is highly significant (two-proportion z -test, p < 10 −5 ), and it yields a ratio for the fixation rate of IS-related mutations per generation in mutator versus non-mutator lines of 0.46.
However, the differences in mean distances within the groups were highly significant ( F = 128.13, P = 0.00001) [ Table 5 ].
The excess of transition paths is highly significant by a binomial test ( P < 10 − 5 ; here and below, we do not distinguish values of P below 10 − 5 ).
The results indicated that the assumption that, for all the cytokines evaluated, irradiation with Fe ions causes an increase in the levels of each of the cytokine evaluated that is highly significant (p value < 0,00001).
1 , Supplementary Figure S1 ).The modules were numbered in increasing order from 1 to 30 according to scores of the clustering algorithm 15 (Supplementary Table S1 ); 1 is assigned to the module with the highest score (most densely connected to each other).Next, we assessed whether genes of the clustered terms are significantly interconnected in physical interactions by comparing each of 30 modules with randomly generated networks having the same gene number of the corresponding module and confirmed the highly significant inter-connectivity of them 12 (Supplementary Figure S2 , S3 , p < 0.00001), meaning that their components are not randomly distributed in the interactome.
Variants were thus discarded if: (i) UCSC alignability ≠ 1 (100bp window size); (ii) variant within 10 bps of a simple repeat region; (iii) highly significant deviation from Hardy-Weinberg equilibrium (HWE) in cases or controls ( P <10 −5 ); (iv) no call rate significantly different between case-samples and control-samples ( P <10 −5 ); (v) no call rate across either case or control samples >0.03.
However, direct effect was highly significant (ANOVA, F (2,65) = 41.47, P < 0.00001).
The Pearson correlation for each metric across the two periods was highly significant ( p < 0.00001) and ranged from 0.86 to 0.92, demonstrating high reliability (Fig. 4 ).