Excerpts

In fact, both correlations are highly significant (p < 0.00001 for each in Fig 2B ).

Results The values of LV-EDV and LV-ESV measured in 3D-ECHO showed highly significant correlations with CMR (for LV-EDV r = 0.892, p < 0.00001; for LV-ESV r = 0.896, p < 0.00001).

This search recovered the GCS2 HMM (based on PDB: 1r8g) as the highly significant best hit (p-value= 10 -5 ), with an alignment spanning the entire length of the GCS2 catalytic domain and matching all key conserved motifs (Fig. 2 ; see below).

Quantitative assays determined using DNS revealed highly significant differences ( P < 0.00001 with Tukey's HSD at 5 %) for cellulolytic activity among the assayed gut bacterial isolates.

Table 3 reports the final hierarchical AMOVA confirming that the northern populations (grouped to be compared with the other populations) were strongly differentiated from those of central Italy with high and highly significant fixation index (Φ CT = 0.666, p<0.00001).

norvegicus was highly significant (P-value <0.00001) by regression of shape onto centroid size for both dorsal and ventral views.

In fluency [ 17 , 18 , 21 , 41 , 77 ], there was a highly significant deficit in SZ (Hedge’s g = −2.03, df = 4, p < 0.00001, CI = [−2.82, −1.24]), but with large heterogeneity within results (84%) ( Figure 2 (2.6)).

This was found to be statistically highly significant ( P < 0.00001).

A z-test of the difference was highly significant z = ( .7428 - .0322 ) / ( 6.737 X 1 0 -4 ) 2 + ( .0022 ) 2 = 314.13, (P < .00001).

The terms for DNA-binding transcription activator activity (RNA polymerase II-specific) and actin binding were highly significant ( p = 1.0 × 10 −5 ), as was microtubule binding ( p = 2.0 × 10 −5 ).

Given the small sample size, nominally significant CpG-smoking associations were defined as having P < 1x10 −5 and were displayed using a ggplot2 boxplot.

There was a strong positive association of Cp biomarker positivity and asthma severity category that was highly significant (P<0.00001).

A correlation matrix was calculated for these genes, using Pearson Product-Moment Coefficient, defined as r x , y = ∑ i = 1 n ( x i − x ̄ ) ( y i − y ̄ ) ( n − 1 ) δ x δ y The values of Pearson correlations above 0.3 are statistically highly significant (p-value < 0.00001 after Bonferroni correction for multiple testing [ 85 ]).

The combined p ‐values obtained for the three hypotheses tested were highly significant ( p < 0.00001) in all cases. 4 DISCUSSION Differences in quantity and quality of the progeny are the most obvious consequences of mating systems and sexual polymorphism, but they are not the only ones.

Our study therefore demonstrated highly significant ( p < 0.00001) recovery of a VH3-enriched set of B cells and our findings therefore confirmed the selection of SpA-binding switched post-germinal center B cells that was solely based on the VH region and was apparently not affected by light chain usage.

S3C ), there was a highly significant difference between all groups when clustered by degree of substrate consumption (Kruskal–Wallis p value <0.00001; Fig.

Association between clinical severity and age groups was highly significant (p-value <0.00001) as presented in Table 4 .

Comparison of Cd, Pb, and Zn accumulation in the red fox ( Vulpes vulpes ) and in two rodent species: the yellow-necked mouse ( Apodemus flavicollis ) and bank vole (Myodes glareolus ) The relationship between Pb concentrations in the soil and in the livers of red foxes and the two rodent species were highly significant ( p < 1 × 10 −5 ).

Logistic regression testing the effect of sequence length on whether or not the query sequence have at least one BlastX hit ( E value 10 -5 ) was highly significant (p-value < 0.00001).

The differences are relatively constant across the subjects, and a paired student's t test returned a highly significant difference between the two conditions (P < 10 −5 ).

These changes correspond to a highly significant ( t (44) = 5.10, p < 0.00001) decrease in average FA in the white matter between left thalamus and left IPL (Figure 2B ).

The meta-analysis revealed substantial between-study variance (Tau2 = 684.19) and a highly significant Chi-squared test for heterogeneity (Chi2 = 330.07, p < 0.00001), indicating that the variation in effect estimates was predominantly attributable to differences among studies rather than sampling error.

At a general hospital level, Hellgren et al., retrospectively analyzing data from 83 patients with RRMS, PPMS, and SPMS, reported a highly significant reduction of ARR induced by rituximab (500 or 1,000 mg every 6–12 months) from mean 0.38 ± 0.5 before treatment initiation to mean 0.05 ± 0.19 at follow-up (p<0.00001), with a global reduction by 87% ( 82 ).

Results Copper levels were higher in group II showing statistically highly significant results compared with that of group I with p ≤ 0.00001.

Notably, even after fitting the lead SNP in a conditional GWAS analysis, there were still other somewhat significant ( p < 1E–05) SNPs remaining for the HTFYslope trait (though not very strong signals; Fig. 2 ), suggesting that they could be other QTLs for heat tolerance, which were not captured by the lead SNPs identified in the study.