Excerpts

Furthermore, the CV-ANOVA p value is highly significant (p = 6 × 10 −7 ), indicating a good model.

Highly significant (median p-value = 6×10 –7 ) pair-wise differences in molecular marker expression were observed for all markers ranging from mature, functional, and synaptic neuron markers to astrocyte, oligodendrocyte, and microglial markers ( Figure 1B ; Figure 1—figure supplements 4 and 5 ; Supplementary file 5 ) – confirming neuronal and non-neuronal cell-type identities in the NeuN + and NeuN - nuclei samples, respectively.

One month after the therapy shift (T3), we detected a highly significant decrease in the BRAF p.V600E and MEK1 p.P124L MAFs ( p = 0.0000006 and p = 0.0005, respectively).

We also found that the CV-ANOVA p -value was highly significant ( p = 6 × 10 −7 ), which indicates a good model.

Furthermore, we observed an extremely significant down-regulation of OsMADS1 (fold-change = 56.7 and p = 6.1 × 10 −7 ), which negatively regulates grain length [ 9 ] ( Figure 9 A).

Because 6 HSPC populations were investigated, this finding was highly significant ( P = 6.106 × 10 −7 ; a binomial test).

Relationship Between Nociceptive Flexion Reflex Threshold, Fibromyalgia Syndrome Diagnosis, and rs4796604 Genotype The correlation between the rs4796604 genotype and NFR thresholds is highly significant ( r T = 0.23, p = 6.12E−07, Kendall’s Tau statistics).

Statistical analysis demonstrated a highly significant difference in methylation for all CpGs within top strand as compared to the reverse strand for CD45RA + CD15s − Treg ( p = 6.15E-07), but not for CD45RA − CD15s + Treg ( p = 0.026091).

From that initial value, the absolute decline is highly significant and similar for each subsequent cycle, in the range of 0.020–0.024 hour −1 ( P = 6.17 × 10 −7 , 9.74 × 10 −7 , 2.41 × 10 −5 for cycles 2, 3, and 4, respectively).

After removal of the data during the Covid pandemic, highly significant interactions were still detected between gender and mobility in first-time donations ( p = 6.2e-07) and between gender and age group in repeat donations ( p < 2.2e-16) ( Supplementary Table S3 ).

This effect was highly significant for both the ipsilaterally-tuned population ( t test, t (68) = 5.5, p = 6.2 × 10 −7 ) o and contralaterally-tuned population ( t test, t (162) = 7.15, p = 2.8 × 10 −11 ). p We found that attend in responses of contralateral neurons, but not ipsilateral neurons, were better described by a WTA model (a linear regression slope of 1 signifies a WTA response; Fig. 6 B ).

Overall, the relative fold-change between BRAF V600E and BRAF wt was about 10 and statistically highly significant ( p = 6.27 × 10 −7 ).

Even though there were highly significant differences between the cfDNA of healthy and breast cancers (p-value = 6.278e-07) and healthy and ovarian cancers (p-value = 2.708e-11), on the individual levels there were many overlapping cfDNA values between cancer-free individuals and cancer patients.

A simple regression model of the relationship was highly significant (p = 6.32e-07) with an R-square of 0.797.

Moreover, age-adjusted partial correlation analysis between relative abundance of Faecalibacterium during infancy and the number of older siblings revealed that this association was highly significant (rho = 0.23; P = 6.4 × 10 −7 ; n = 482).

This demonstrated a highly significant difference in the distribution of PD (right-shifted) in high CRP (> 3 mg/L) versus low CRP (< 3 mg/L) depression cases (Kolmogorov-Smirnov test, P < 6.4 × 10 −7 ) and between high CRP depresssed cases and controls (Fig. 1A ).

One association reached borderline significance (p = 6.41∙10 −7 ) when using the RAVA-FIRST strategy, i.e. with CADD regions and the corresponding ACS filtering.

Regression analyses of the log-transformed ratio of archaeal to bacterial 16S rRNA gene copies indicated a highly significant and inverse relationship with pH ( β =−0.22, adjusted R 2 =0.29, P =6.42 x 10 −7 ; Supplementary Figure S1 ) but no significant correlation with temperature ( β =0.00, adjusted R 2 =−0.01, P =0.83).

The three major effect regions on chromosomes Vu02, Vu08 and Vu10 that displayed highly significant associations for aphid resistance were represented by peak SNPs 2_24304 [−log (p) = 6.19], 2_22525 [−log (p) = 10.37] and 2_43876 [−log (p) = 13.19, respectively ( Table 3 , Supplementary Materials Table S2 ).

With normality satisfied, the paired t-test shows a highly significant change: p = 6.48 × 10 −7 .

The difference in social class between reproducing and nonreproducing trees was highly significant (Mann–Whitney U test, U = 5,308, p = 6.5 × 10 ‐7 ).

This difference was highly significant (Fisher’s exact test, p=6.50×10 - 7), with an odds ratio of 0.106 (95% CI (0.038, 0.281)), indicating that the odds of a positive biopsy were approximately 90% lower in patients with a confounding cancer (Table 2 ).

3a ), we first carried out multinomial logistic regressions, which revealed a highly significant interaction ( p = 6.5 × 10 −7 ; likelihood ratio test) between compartments (i.e., bush, psyllid, orchard) and regions (i.e., PO, BR, VA).

This correlation of function with polymorphism is highly significant for HLA-A ( p = 6.52 x 10 −7 ) and HLA-B ( p = 1.18 x 10 −6 ), but less so for HLA-C ( p = 0.0124) (2 x 2 Fisher’s Exact test).

Our custom pathway enrichment (comprising Gene Ontology and KEGG databases) analysis of the impacted genes within the CNV breakpoints of all pathogenic deletions identified “ubiquitin-like protein transferase activity (GO:0019787),” “negative regulation of cell death (GO:0060548),” and “vesicle-mediated transport in synapse (GO:0099003)” pathways to be highly significant (FDR p < 6.53 × 10 −7 , FDR p < 7.2 × 10 −6 , and FDR p < 7.1 × 10 −5 ) after correction for multiple tests ( Figure 3A ).