This analysis revealed a set of common SNPs located within the 5′-upstream region of the gene that showed nominally significant correlations between genotype and RAI1 mRNA expression in both brain regions ( Fig. 1 ).
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Surprisingly, during this time period, the MG density of the lip (r) in the LMC dropped significantly, and the lip (r) in the RMC showed a trend of decreasing MG density (see Fig. 4 ).
ECC prevalence by age The pooled results of 91 articles indicated that the overall prevalence of ECC for children aged 1–6 years was 0.3%, 17.3%, 40.2%, 54.4%, 66.1% and 70.7%, respectively ( Table 1 ), showing an increasing trend with age ( Fig. 3 ).
Cytokine selection and validation We selected cytokines based on the following criteria: 1) showed at least a 2-fold higher (FC ≥ 2) or lower (FC ≤ −2) expression in the exposed group compared with the control group; 2) with highly significant differences in expression ( q < 5.00%) between exposed and control group; 3) with signal values higher than 500 in each individuals; 4) were found to be involved in inflammation processes and/or be related to PM/PAH-mediated cardiovascular risk based on an extensive literature review.
Nevertheless, the interaction between IOP and axial myopia on POAG was of borderline significance ( P for interaction = 0.066).
extremely significantqualified
P < 0.05 was set as statistically significant, whereas P < 0.01 was considered extremely significant.
Under the default setting of the weighted gene co-expression network analysis (WGCNA) program 22 , the above 87,588 nominally significant CpGs ( P nominal < 0.05) identified in male AUD subjects were clustered into 21 modules ( Supplemental Fig.
Titration of the total viral RNA copy number and the transduced proviral copy number showed a trend towards reduced vector titre as the length of packaged sequence increased.
An increase in macromolecules at 0.9 ppm trending towards significance has been reported previously in response to a pro-inflammatory 1 mg/kg LPS dose in developing rats 18 .
This is highly significant for speciation of deep C–O–H fluids with potential consequences for fluid-carbonate-bearing rock interactions.
To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ Solar conversion to fuels or to electricity in semiconductors using far red-to-near infrared (NIR) light, which accounts for about 40% of solar energy, is highly significant.
Interestingly, when the dissolution rates of these solids are cast as a function of the number of atomic constraints for a given (fixed) solution pH – a significant trend results as shown in Fig. 4(a) .
extremely significantqualified
Moreover, the alkaline buffer is critical and important as it is the only constituent of the internal microenvironment of a UCU delivery system and the effect of environmental pH on the enzyme activity is extremely significant.
A p -value < 0.05 was considered statistically significant, and p < 0.001 was considered highly significant.
Observational temperature data for the past 100 years or so suggest an increasing trend in global mean temperature.
The use of natural products as auxiliary agents is an important trend in cancer research and has the goals of increasing the efficacy of present cancer treatment, lowering toxic effects and alleviating side effects.
Within the emotional features, predictive power of an image’s valence and arousal differed across perceived referents (valence significant for knife; arousal significant for dolphin), and just failed to reach significance during imagery for the knife referent.
The Rb/Sr ratio exhibits a decreasing trend within the reddish LPS ( Fig. 3 ), reflecting the long-term intensification of aridification in the NIGP from ~2.4 to 1.8 Ma.
integrifolia in the good patches showed a trend to overwhelm that in the bad patches, although this tendency was not statistically significant ( P = 0.071, Fig. 2b ) when the within-patch quality contrast was low and the between-patch contrast was high (treatment L-H).
The CEC ratio in placebo group exhibited an increasing trend whereas that in LC group declined.
In the second study, five AAs were differentially expressed in three groups, lean, obese, and obese with diabetes, with an increasing trend (i.e., HL < OW/OB < DM).
a clear trendgold
It is apparent that γ < 2 with a clear trend in which γ approaches 0.2 as the system approaches the exponentially localized state.
2C ) showed insignificant or only marginally significant differences in distances.
The method described here may be significant for the development of microparticle-based applications such as self-assembled materials 1 2 3 , self-propelled micromotors 4 5 6 7 , drug delivery systems 8 9 , and environmental engineering 10 .
extremely significantqualified
Such overlaps were extremely significant compared with a random one (see Table 1 ).