Excerpts

The analysis indicated that CENPA expression was positively correlated with TMB and MSI across most cancer types, though the correlations were weakly significant ( S2A , S2B Fig ).

We examined the nonlinear relation of AFB with RA and detected a notable trend ( Fig 2 ).

However, there is likely to be significant sub-national variation.

With the increase in hydrogen content, the depth and size of dimples on the fracture surface exhibited a decreasing trend, indicating a gradual deterioration of plasticity.

Fifthly, although the time-varying ΔCoVaR plots differ among the routes, there is a clear trend: the absolute values of ΔCoVaR significantly increased from 2020 to 2022.

However, no attempt was made to estimate the social and economic consequences of AMR in Kazakhstan, even though they are likely to be significant.

However, after the takeoff point (0, 0), the UAV gradually follows the target and shows an overall trend of tracking the target.

In addition to this, we found that the overall annual incidence rate of PTB showed an overall trend of downward.

We describe the effects of other (control) variables, which are often highly significant, in the Supporting Information.

Even in instances of nominally significant genes only moderately exceeding chance expectations by FDR, the nominally significant genes were found in downstream enrichment analyses (involving functional gene sets and results of external SARS-CoV-2-related RNA-seq datasets) to contain biological information.

Overall, the intensity of construction land expansion (Z-axis) within the central urban area of Chongqing exhibits a decreasing trend from west to east (X-axis) over time.

While both regions fall under the Americas classification, there might be significant cultural and socio-economic differences.

According to the world Bank, this shift toward cheaper meals is a significant trend in Senegal [ 47 ], aligning with our findings.

Introduction The integration of global shipping network into the global economy has been a significant trend, fostering diverse industries involved in intra-regional and foreign trade [ 1 – 4 ].

Moreover, the coefficient of allometric growth in the YRD showed a decreasing trend from 2009 to 2022, with a decrease of 3.61% for bed resources and 11.13% for physician resources.

Overall, the development of healthcare resources in YRD cities mirrors economic trends, demonstrating a significant trend towards centralization.

The economic and health resources of the YRD cities exhibit a spatial distribution characterized by being "high in the east and low in the west, high in the south and low in the north." This pattern is accompanied by growing advantages in the central cities of the region in terms of economic and health resources, reflecting a spatial pattern of "one pole and many nuclei." Both the numbers of doctors and beds in the YRD region showed a trend toward relative equalization.

By constructing regression models, we identified glyphosate exposure as a risk factor for ASCVD, and linear fitting revealed an increasing trend in ASCVD incidence with higher levels of glyphosate exposure.

After 3h, the overall resistivity of the medium shows an increasing trend, but the main changes occur in the upper part of the medium before 15h.

With the injection of LNAPL, the resistivity of the lower layer of the medium shows a negative increase from 0h to 2h, indicating a decreasing trend in resistivity.

However, there is an increasing trend of endometrial cancer in most LMICs because of increased prevalence of major risk factors such as obesity and low fertility rates [ 2 – 4 ].

A positive value of Qi suggests an increasing trend, and a negative value of Qi offers a decreasing trend in the time series.

The MMK test showed that the annual rainfall during the Kiremt (summer-main rainy season) had an increasing trend.

The significance of a trend is calculated by the Z-score using: { o Z = s − 1 v a r ( s ) , i f s > 0 Z = 0 , i f s = 0 Z = s + 1 v a r ( s ) , i f s < 0 (9) When Z value exceeds either of the confidence limit lines, it shows a significant trend at a given significance level.

A Chi-squared goodness-of-fit test was then conducted, and the highly significant test statistic indicated a model with poor fit [ 26 ].