Excerpts

Note that rs2071861 was only nominally significant ( P = 0.019, Table 3 ) in the discovery phase.

A McNemar test with a Bonferroni correction for multiple tests showed a trend toward the reduction of the proportion of patients with FSS score ≥4.5 after 1 ( p = 0.019) and 2 years ( p = 0.021) in comparison to baseline value.

In particular, the difference between Group 1 and Group 3 was highly significant [median: 37.28 (IQR: 33.53–38.37) vs 16.06 (IQR: 9.979–29.27); p = 0.0193].

In the case of PRELID1 , there was a significant trend (R = 0.3932; p = 0.0196) towards higher copy number assignments for samples with DNA input amounts above the average (13.28 ng; range 2–120 ng) of the sample set ( Figure 3 ), even after removing outliers (>75 ng input DNA).

The efficacy of combination therapy was highly significant when compared to ABT-737 (p = 0.0198) and 9.2.27-PE38KDEL monotherapies (p = 0.0100; Fig 5A ).

The gene-based analysis confirmed the significance of the THRB gene ( P = 2.29×10 −5 ) and showed a borderline significance for the PVT1 gene ( P = 0.02) ( Table 3 ).

However, moderately significant linear relationships were detected between bleaching (loss of Chl a ) and chronic photodamage (reduced F v / F m ) in both H. depressa (R 2 = 0.532, p = 0.020) and M. vertebralis (R 2 = 0.300, p = 0.034) (data not shown).

A total of 603 TT and 5 TC carriers were identified in the patient group, resulting in an association with marginal significance (P = 0.02), which does not survive the multiple test corrections.

[22] showed marginal significance of AMD with ΔCNP147 after adjusting for key SNPs such as rs1061170 and rs10737680 or rs2274700 (p = 0.02 and 0.044, respectively).

At baseline (t = 0), the ratio differed between diets (p = 0.02); it was higher with the LF diet than with the LGI diet (p = 0.015), and higher with the LF than with VLC diet, with borderline significance (p = 0.02).

We found that the degree distribution of the subpathway nodes of the actual DMSPN was significantly broader than that of the random networks (P-value<10e–10, see SI Figure S2A ), whereas the distribution of disease nodes did not display such a highly significant difference (P-value = 0.02, see SI Figure S2B ), suggesting that the different subpathways in the DMSPN possessed the considerable differences with respect to causing diseases.

Although a likelihood ratio test suggested no significant multiplicative interaction between miR-16 and miR-21 (p>0.05), there was a significant trend for increased risk of being classified as SGA from having only miR-21 reduced or only miR-16 reduced in expression to having both reduced in expression (p<0.02).

Individuals who consumed more coffee presented marginally significant more RA of Fusobacteria ( P = 0.02, FDR = 0.20) in their gut microbiota compared to those reporting low or no coffee intake, but the RA of Fusobacteria was significantly higher in smokers compared to non-smokers ( P = 0.009, FDR = 0.027).

Serum Ang-1 levels did not change significantly in cholecalciferol group (mean change: 1.36 ng/ml; 95% CI: -2.39 to 5.11 ; p = 0.280; Table 3 ) while in placebo group showed an increasing trend (mean change: 5.63 ng/ml; 95%CI: 0.51 to 10.75; p = 0.020).

Combined effect between CD14 rs2569190 and delivery mode has a significant trend P-value (P = 0.02).

The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend ( p = 0.02).

[36] In a similar group of NSCLC patients, the results of the TAILOR trial indicated a highly significant increase of PFS in favor of docetaxel (HR = 0.71; 95% CI, 0.53–0.95; p = 0.02) versus erlotinib.

When different types of dairy consumption were investigated separately for CVD, CHD, fracture, or all-cause mortality events, a significant trend of lower risk of fracture with increasing total fermented dairy consumption (adjusted model P = 0.02) was observed, with HR of 0.67 (95% CI: 0.50–0.90) for the highest (total fermented dairy>133 g/week) vs lowest (0≤total fermented dairy≤26, g/week) quartiles of total fermented dairy consumption ( Table 3 ).

A multiple regression model of parasite prevalence on both elevation and temperature was highly significant (F 2,3 = 164.63, P<0.02, R 2 = 0.99, Adjusted R 2 = 0.98) but only temperature contributed significantly to the model (temperature: Beta = 0.99 P = 0.02; elevation: Beta = 0.004 P>0.98).

High APOBEC3C expression remained significant in anaplastic astrocytoma and showed a trend toward significance in anaplastic oligodendroglioma even when the model was adjusted for age (p = 0.02 and p = 0.07, respectively) ( Table S12 ).

The 2 group×3 stem type ANOVAs on response time to speech stimuli yielded marginally significant main effects of stem-type (F1(2,68) = 4.64, p<.02, F2(2, 29) = 2.20, p<.13).

Moreover, there was a significant trend of birds molting during the non-normal months between 2000 and 2006 ( Fig. 2 , trend, p = 0.02), whereas no trend existed before 2000.

Further, we observed a borderline significant association between ghrelin levels and post-vaccination antibody levels in overweight children (regression coefficient 0.009, p = 0.02) ( Table 3 ).

Both models show that the telehealth related factors are the most contributing features in predicting Effort Expectancy except for Self-Efficacy (SE) and Perceived Barriers (PB) where PB has a low contribution by lower IV, although it has a highly significant effect (a dashed border bar) on Effort Expectancy, inferred by p = 0.02 in Table 4 .

The results showed how the server was significantly closer to the net using a conventional formation when the returner hits the ball at the beginner level (U = 63543; Z = -4.0; p < .001; d = .34) and almost significantly at the high level (U = 1333599; Z = -2.3; p = .02).