Excerpts

Since the mechanical studies in STAT3-OKO-M mice all yielded highly significant effects (p<0.005), while the studies in STAT3-OKO-BL, despite similar effect sizes, did not achieve the 0.025 threshold, we sought to further confirm our prediction of defects in intrinsic parameters consistent with altered bone quality by determining whether meta-analysis of the combined studies yielded significant effects.

Corresponding Mann-Whitney U tests were highly significant (all p < 0.005), and these associations withstood adjustment for multiple testing.

If all the results are compared as a whole, we find that PLD2KO mice have a highly significant 5% more of the C36: species in all brain regions (see Fig 1G , p<0.005).

Patients with CDI + UC showed a trend of increasing relative abundance 3-mos. post-transplant (12.23, 95%CI 4.17 to 20.28, p = 0.005), but did not reach significance with the Bonferroni correction.

Statistical analysis revealed that these differences were highly significant (p<0.005).

NOS3 G894T (rs1799983) showed a nominally significant association prior to correction (OR = 0.68, 95% CI: 0.52–0.89; p = 5.069e-3), but did not survive Bonferroni adjustment (p-Bonferroni = 4.5621e-2) and should be interpreted with caution.

This interaction is suggested, but not substantiated, by the near-significant statistical interaction between these factors: two-way ANOVA, F (1,88) = 8.251, p = 0.0051 for Aβ; F (1,88) = 0.8809, p = 0.3505 for htau; F (1,88) = 3.056, p = 0.0839 for interaction.

The virus-mediated activation resulted in a highly significant 1250- to 7000-fold luciferase induction (p = 0.0051 upon HCMV-AD169 infection of pTA-Control transfected cells).

In the reviewed version we removed results for LTAa 322 (marginally non-significant, p=0.0052) which prompted us to reformat the table.

There was some protein loss in the SDS-treated samples, reaching significance (p<0.001) in the 1% concentration group and approaching significance (p = 0.0052) in the 2% group.

The gene encoding for IL17A was also expressed stronger in bTb infected cattle compared to TB-free cows, although its expression was not quite statistically significant (P = 0.0052, Table 1 ).

Individual ANOVA tests were performed on the VTA X and VTA MST populations which indicated highly significant changes in cell counts across age groups (VTA X population ANOVA, p = 0.00537; VTA MST population ANOVA, p = 0.012).

The difference in the proportion of identified proteins in the GlyGly search was nearly significant (p = 0.0054).

This stunning difference in the numbers of sites of the three site classes were highly significant between intron 2 and the remaining part of the gene (χ 2 : p=0.0055, power=1.0000), and the differences between the subregions were also statistically significant (intron 2 vs. non-cds without intron 2, χ 2 : p=0.0106, power=1.0000, intron 2 vs. cds, χ 2 : p=0.0091, power=1.0000, cds and non-cds without intron 2, χ 2 : p=0.0423, power=0.9989).

Only April showed a significant trend in BPH over the 10 years with a slope of 0.1540 per year ( P <0.0057).

Following corrections, PCT remained a highly significant predictor for secondary bacterial infection, positive blood (OR = 1.62, CI [1.15, 2.28], p = 5.8E-03) and sputum cultures (OR = 1.44, CI [1.10–1.89], p = 8.7E-03), as well as for ventilation (OR = 1.47, CI [1.22–1.77], p = 0.000039), death (OR = 1.39, CI [1.15–1.69], p = 0.00077), and ICU admission (OR = 1.48 CI [1.23–1.78], p = 0.000036) by day 28.

Time matching within reciprocated grooming bouts Analyses of all reciprocated grooming bouts suggested that the relationship between the amount of time each initiator spent grooming the recipient and the amount of time the receiver reciprocated was extremely significant (weighted least-squares regression analysis, F 1,102 = 7.91, p = 0.0059).

Proportions of nonclassical monocytes were lower amongst this higher income bracket with lower intermediate monocytes trending towards significance [nonclassical fold change -5.23 (95%CI -8.94 to -1.53), p = 0.006; intermediate -1.91 (-3.91 to 0.10), p = 0.063].

The differences were highly significant between the groups; B and S ( p = 0.006), T and S ( p = 0.005) and B and T ( p = 0.001).

The second GWAS SNP, rs12425791, was only borderline significant based on our threshold of one expected false discovery (HR = 1.31, p = 0.006).

Stratified analyses showed that the association between urinary BPA levels and PCa is highly significant ( p = 0.006) among the 30 patients <65 years old (mean and median age = 58, minimum age = 46) but that this association does not reach significance among the half of patients >65 years ( Fig. 1 ).

Comparison of binding parameters revealed a highly significant (p = 0.006) decrease in competitive potency for MLA+T30 (IC50 = 15.5±0.7 nM) as compared with MLA alone (IC50 = 9.5±0.4 nM; Fig. 3D ).

The inter-individual comparison in PD patients between the clinical dominant and non-dominant side showed a highly significant difference of the grey value vessel ratio for veins ( p -value = 0.0060): The non-dominant side showed a lower contrast in veins compared to the dominant side.

There was a highly significant interaction between OPV at birth and sex (p = 0.006).

chumash were highly significant in the presence of predation (main effects of host, F 1,20 = 9.63, p = 0.006), but not in its absence (main effects of host, F 1,20 = 2.02, p = 0.17).