Barely Significant

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a decreasing trendp < 0.0010.0× alphagold
The serum-UA levels of mice in different treatment groups showed a decreasing trend after gavage administration, among which the positive control group and the HPO group showed excellent UA-lowering efficacy (*** p < 0.001); no statistically significant difference was observed in the comparison between the groups ( Figure 5 A).
highly significantp = 0.0020.0× alphaqualifiedgold
The pH value of fasting-morning urine correlated directly and significantly with potassium excretion ( R = 0.33, p = 0.02) but not with 24 h citrate levels ( R = 0.09; p = 0.58) while a highly significant correlation between potassium and citrate excretion was found ( R = 0.47, p = 0.002).
moderately significantp = 0.0020.0× alphaqualifiedgold
The separate analyses of linear correlation in subjects without and with colorectal lesions revealed a moderately significant positive correlation in those without lesions between feces putrescine and spermidine ( r = 0.685, p = 0.002, n = 18), N -acetyl putrescine ( r = 0.606, p = 0.008, n = 18), and cadaverine ( r = 0.591, p = 0.01, n = 18).
highly significantp = 0.0020.0× alphaqualifiedgold
Highly significant improvements were found in sprint 1 ( p = 0.002, 95% CI [0.032, 0.132], ηp 2 = 0.195), sprint 2 ( p = 0.001, 95% CI [0.018, 0.064], ηp 2 = 0.029), sprint 4 ( p = 0.000, 95% CI [0.097, 0.225], ηp 2 = 0.353), dribbling layup time ( p = 0.009, 95% CI [0.019, 0.124], ηp 2 = 0.152) and total completion time ( p = 0.000, 95% CI [0.446, 0.785], ηp 2 = 0.366). 3.3.2.
highly significantp = 0.0020.0× alphaqualifiedgold
Additionally, blood urea nitrogen (BUN) levels increased significantly in the intervention group ( p = 0.020), while BUN levels did not change significantly in the control group ( p = 0.070), resulting in a highly significant intergroup difference in BUN changes ( p = 0.002).
a decreasing trendp = 0.0020.0× alphagold
The mRNA expression of CYP27A1 and CYP27B1 were upregulated in the VDD group ( p < 0.001), VDR had a decreasing trend compared with the CON group in the brain; while the mRNA expression of CYP27A1 ( p = 0.002, p < 0.001) and CYP27B1 ( p = 0.008, p < 0.001) were downregulated, VDR ( p = 0.044, p = 0.010) was upregulated in the VDD + VD group and VDD + VD-FA/VB 12 group compared with the VDD group in the brain.