Barely Significant

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highly significantqualifiedgold
There was a highly significant dependence of responses to males on the response to females (all: p subject _ sex < 0.001), and the estimate of the slope was significantly smaller than unity, suggesting that responses to females are stronger in magnitude than responses to males (VMC/S1/A1: β subject_sex [CI] = [0.27–0.49]/[0.54–0.78]/[0.45–0.078], Fig. 5b ).
Asthma and eosinophil count were chosen as relevant traits, as they are both ubiquitous features of EGPA, and genetic variants showing association with them showed a trend for greater association with EGPA (Supplementary Fig. 2 ), with a consistent direction of effect (Supplementary Table 4 ), suggesting shared genetic architecture.