Excerpts

Sox10+ cells with Opalin expression show a decreasing trend in the tumor core without reaching significant differences (Fig.

Gria1 expression was similar between the two groups at 7–9 weeks but showed a trend toward downregulation in AR-97Q mice at 10–12 weeks of age (Supplementary Fig. 8h ).

amalonaticus recipients showed a trend towards direct correlation between the side chain size (i.e. the bigger the side chain the greater the conjugation efficiently) (Fig. 5A-E , Table 1 ).

Even though not statistically significant, there was a trend toward significance for mMSS and high-risk L-CHIP genotypes compared to other L-CHIP (Fig. 4D , Supplementary Fig. 5 and Supplementary Table 9 ).

Genome-wide comparison of PU.1 binding demonstrated an overall trend of increased binding in OCR HSCs compared to OAL HSCs, which normalized after refeeding (Fig. 5d ).

Predominant gut-associated archaea show an increasing trend in certain diseases, such as CRC Next, we investigated if specific archaeal species are more prevalent in disease compared to the control.

We next sought to identify microbial genera that exhibit a significant trend in abundance across the normal, polyp, and tumor.

In contrast, CX3CR1 low were linked to increased CD4 + T cell activation, proliferation, and exhaustion, and showed a trend toward Th1 expansion and enhanced CD4 + T cell recruitment.

17 plots the decay time as a function of P eff , showing a decreasing trend with increasing irradiation power.

Although FAO dependency did not differ significantly across genotypes or treatments, a mild trend toward increased FAO reliance was observed in TNF-treated SNCA 3x ENLs under CSB6, potentially reflecting partial restoration of metabolic flexibility 74 .

In contrast, the frequency of miniature GABA-mediated events showed a trend towards a decrease in MPS IIIA (Fig. 5P ).

We found no significant effect of response presence on measured spine volume, although we observed a weak trend toward slightly larger volumes during responding sessions (Fig.

MrkD W59C showed a trend towards increased lung cell attachment, while the capsule-deficient mrkD :: IS5 mutant attached better to bladder cells.

This identified highly significant decreases in multiple pathways that govern male gametocyte development within the ∆PfDPL parasites (Fig. 3f , Supplementary Fig. 5g and Supplementary Data 4j, k ).

This challenge is likely to be significant due to the high surface-to-volume ratio of 2D materials, rendering interfacial adhesion energy particularly sensitive to environmental exposure.

Additionally, we observed a prominent cumulative modulation effect: theta suppression following the final train was significantly greater than that following the 1st, 3rd, and 4th trains (1st: t (17) = 6.16, p FDR = 1.06e − 04, 95% CI = [1.40, 2.86], Cohen’s d = 1.38, 1− β > 0.99; 3rd: t (17) = 2.95, p FDR = 0.030, 95% CI = [0.74, 4.50], Cohen’s d = 0.66, 1− β = 0.79; 4th: t (17) = 4.91, p FDR = 6.50e−04, 95% CI = [1.38, 3.44], Cohen’s d = 1.10, 1− β > 0.99), and showed a trend of stronger level than the 2nd train ( t (17) = 1.94, p FDR = 0.14) (Fig. 5C ).

Consistent with prior findings 12 , activation of the pathway by RNAi knockdown of the phosphatase vhp-1 or overexpression of sek-1 and atf-7 showed a trend toward increased catp-3 mRNA expression, suggesting that p38–ATF-7 signaling may contribute to catp-3 transcriptional regulation (Fig. 5a ).

However, a notable trend emerges with ZSM-5-650: the selectivity toward ethylene, the primary dehydration product, decreases as the temperature increases.

While total ubiquitylated protein levels showed a trend toward decreased accumulation, K48-linked polyubiquitylated protein levels were significantly reduced in NACET-treated brains (Fig. 5D , Fig.

These results revealed that the Mn-hCaO 2 /hZIF8/SMA hydrogel can modulate the M1/M2 ratio, which in turn can produce highly significant changes in the cytokine network in the niche and steer the environment towards a pro-regenerative state.

EC prediction performance showed a trend toward higher values during renewal compared to acquisition; however, renewal did not differ significantly from either acquisition or extinction after correction for multiple comparisons ( z s < 1.55, p s FDR > .10).

Similarly, in the behavioural studies, learning was highly significant at the group level during both acquisition ( z = 19.75, p FDR s < .001, d = .37, CIs = [.61, .75]) and extinction ( z = 16.11, p FDR s < .001, d = .53, CIs = [.84, 1.07]), with only 2 out of 180 individuals showing slight negative trends (see Fig. 3E ).

Statistically significant sex interactions were seen in the long ( P for interaction = 0.015) and medium ( P for interaction = 0.048) baseline sleep duration groups, though the latter showed only marginal significance.

In our cross-cohort meta-analysis we observe a trend towards protective associations with several cardiometabolic traits, including a nominally significant association with lower waist-to-hip ratio following adjustment for BMI—a phenotype causally linked to cardiometabolic health 47 , 48 —and a borderline significant association with reduced HbA1C levels (Supplementary Fig. 4 ), which may warrant further investigation.

By contrast, mice with Htr2c loss-of-function in D2-MSNs showed a trend toward increased locomotor sensitization and exhibited an enhanced place preference for cocaine compared to Rosa26 controls (D2-sgHtr2c and D2-sgRosa, respectively; Fig. 3g–j ).