Excerpts

The model p-value was less than 0.0001, indicating that the model was highly significant, acceptable and suitable for this experiment.

Despite small structural differences occurring within the analyzed groups of compounds, there are quite significant variations in their docking poses ( Figure 6 ).

Accordingly, the precursor, fatty acids, showed a highly significant decrease in their levels.

Further identification of different metabolites responding to MeJA by 1 H-NMR showed an extremely significant increase of the lobetyolinin level, which coincided with lobetyolin.

The F-value of the model was 19.89, showing that proposed model was highly significant, which is double confirmed by the low P-value of 0.001.

These data demonstrate highly significant differences in metabolite profiles based on development stage.

In addition, the compounds 3a , b , 5a , 7a , b , 9b , 11a , and 12a had slightly significant effects with IC 50 values ranging from 14.1 to 38.5 μg, the compound 3a indicated a slightly noticeable effect on HePG2 cells with IC 50 of 6.1 μg, and the compound 12a had weak toxicity on HCT 116 cells with IC 50 of 46.1 μg.

Magnetic behavior showed a clear trend from superparamagnetic to paramagnetic behavior as the amount of oleic acid in synthesis increased.

Interestingly, it was found that there was a highly significant correlation between improved sexual function and performance (decrease in ASEX score) and anxiety reduction in the whole sample.

AXP and MP show an increasing trend while GP decreases under the treatment of enzyme and ethanol precipitation.

In 67% ethanol precipitate, AX showed a decreasing trend to around 200 mg/g while AG increased to more than 64.60 mg/g.

There is an increasing trend of applying CDs in the pharmaceutical, cosmetic, and food industries [ 14 ].

Despite being not statistically relevant, LX2 cells treated with FFA showed an increasing trend in ACTA2 (α-SMA) expression until 96 h and a sudden drop after 144 h.

We thus selected a stricter p -value cut-off of <0.001 to identify highly significant relationships ( Table S1 , Figure S1 ).

control) after exposure to tunicamycin ( Figure 1 ), whereas GPR55 expression was unaffected and TRPV1 expression showed a trend towards decrease, though not statistically significant ( Figure 1 ).

However, the tear strength does not show a clear trend due to the dependence of several factors.

As shown in Figure 3 A, the apparent viscosity of the emulsion showed a decreasing trend with the increase of the shear rate.

Interestingly, treatment did not produce any variation in plasma CoQ 10 content in the diabetic monkeys, while non-diabetic monkeys showed a trend towards a decline in plasma CoQ 10 , which was restored after the wash-out period ( Figure 3 A).

Compound 10 appears slightly more active than 1 and 11 , in agreement with slightly lower BDE values (BDE of 82.0, 82.4, and 82.5 kcal.mol −1 for the three compounds, respectively); however, both from theoretical and experimental points of view these differences are almost insignificant.

Previous studies on tuna oil concentrates have revealed that the regression models for total FA yield and total EPA+DHA content were highly significant with satisfactory R 2 coefficients [ 14 , 22 ].

In the present study, compared with the MOD group, AICAR significantly increased, and the level of AMP also had an increasing trend, after VT intervention ( Figure 4 ).

That study found that tri-herbal combination induced a highly significant improvement in both objective and subjective parameters of AD.

Some compounds, such as o -cymene and γ-terpinene, are present in different amounts in F1 to F3 and are almost insignificant in F4 and Unoil.

Finally, the results of the ANOVA analysis run by the Modde 5 software showed significant F-values (60.74 and 49.66, respectively, P = 0.000), indicating that the model terms were quite significant ( Table 2 ).

The p -value of solasodine was much smaller than 0.0001, indicating that the corresponding coefficients were highly significant.