Excerpts

Alamandine levels showed a decreasing trend across groups, with the lowest concentrations observed in patients with severe CAD [62.5 (44.4–87.0) pg/mL], followed by non-critical CAD [70.4 (55.6–110.6) pg/mL], and the highest values in the controls [81.3 (53.9–121.1) pg/mL].

The remaining nominally significant associations—Phoenixin-14 with body mass index ( r = 0.382) and weight ( r = 0.361), Alamandine with glucose ( r = 0.308), and Cerebellin-1 with triglycerides ( r = 0.262)—did not retain significance after correction for multiple comparisons ( Table 3 ).

Although several mRNAs and miRNAs showed nominally significant correlations with age or AAK grade, only a limited number of these associations remained significant after correction for multiple testing.

In addition to the reduction in mPAP, ECJ at 150 mg/kg significantly reduced RVHI compared with the HPH model group ( p < 0.05), whereas lower doses showed a decreasing trend, suggesting attenuation of HPH-induced right ventricular hypertrophy.

A decreasing trend in RTL that was not statistically significant was determined in 64Q cells at seven days of dox-mediated induction of polyQ ataxin-7 ( Figure 3 e).

An increasing trend in p21 mRNA expression levels, which lacked statistical significance, was observed in 64Q cells ( Figure 4 b) in comparison to 10Q cells.

In the third ECT study, the longitudinal EWAS identified nominally significant differentially methylated positions and regions in genes implicated in psychiatric and immune-related processes, including ADARB1 and SLC25A24 .

For Limosilactobacillus (Lb) reuteri LMG (isolated from a commercial probiotic product), the p -value of 0.090 indicates a trend toward significance, but it does not reach the conventional threshold of 0.05.

Regarding apoptosis, treatment with RE showed a trend toward increased early apoptosis in 12-Z cells, although this effect did not reach statistical significance.

CDK2 expression demonstrated a decreasing trend in both PC-3 and DU145 cells.

Nevertheless, p-AKT showed an increasing trend at higher concentrations, particularly at 200–300 μg/mL, while CDK4 protein levels remained relatively unchanged in DU145 cells.

After looking closely at recent studies, one can see a clear trend: the field is gradually moving away from empirical descriptions and toward quantitative, standardized measurements.

In our study, individual treatments show a positive trend in improving kidney function, but only when applied simultaneously, APO and NOV results in visible kidney recovery as assessed by histological findings.

The binding energies show a clear trend of increasing stabilization with greater fluorination of the benzene dimers.

This approach allows for the observation of a clear trend whereby increasing concentrations of the drug are associated with a progressive decrease in the number of dividing nuclei, indicating a concentration-dependent effect on cellular proliferation.

LNCaP cells also showed an increasing trend in proton leak, which may be linked to damage to the inner mitochondrial membrane [ 51 ], and non-mitochondrial respiration typically increases with cellular stressors such as ROS.

Examining the variation in the band gap with the ionic radius of the M-site cation reveals a clear trend: as the ionic radius increases along the series Li < Na < K < Rb, the band gap systematically decreases.

As Figure 2 shows, the recent finding of a putative IRE within the 5’-UTR of α-syn mRNA [ 186 ], as encoded by exons 1 and 2, is highly significant.

An early study in the 1960s that showed an overall trend toward increased disease severity with plaque burden [ 23 ] has been refuted in a number of subsequent studies [ 24 – 26 ].

The metathesis activity showed a decreasing trend with catalyst 1 according to the solvent/anion order BF 4 − > NTf 2 − ~ PF 6 − .

This might be significant in the context of ischemia, in which intracellular Ca 2+ overload has been implicated as a primary mechanism of neuronal injury [ 35 – 37 ].

E40K was also nominally significant for triglycerides in the Mexican American populations even with a very small count of nine heterozygotes carrying the K variant (haplotype H96).

In this case, for several previous transitions, an increment on the phase-shift average value implies an increasing trend in the future.

Phenolic compounds have been suggested to be the main antioxidants in honey as highly significant correlations between total phenolic content and antioxidant and antiradical activities of honey have been reported [ 20 ].

Experimental results carried out on real LCD images have indicated that the proposed QK-SVDD substantially improves generalization performance of SVDD in the LCD inspection application, and the improvement in generalization performance is considerably significant, over 30%.