Excerpts

The fixed-effects test for the subgroup differences suggests a trend toward significance (statistic = 4.00, df = 1, p = 0.052).

Recruitment was higher in the MSt compared with both the HC and the NC (F (2,20) = 36.95, p < 0.0001), with marginally significant group x region interaction (F (2,20) = 3.43, p = 0.052; “group” refers to Control/ALAN groups, “region” refers to MSt/HC/NC).

Sirius red staining on formalin-fixed sections showed that fibrosis around adipocytes (i.e., pericellular fibrosis) was 1.7-fold higher in SAT samples from MetS+ individuals ( p = 0.008), while a nonsignificant trend ( p = 0.052) was found in VAT ( Table 2 and Figure 1 C). 2.3.

LMNB1 mRNA levels showed a statistical trend to be different across AD severity groups ( p -value = 0.052), as shown in Figure 1 B, being the high ABC stage in the group with top expression.

This effect is quite close to significance (test for trend, p = 0.052).

ST32db showed a trend toward decreasing SREBP1 protein levels relative to the control group ( p = 0.052).

Furthermore, in the univariate analysis, MAN1C1 high expression showed a trend association with better overall survival ( MAN1C1 high: 0.74; p = 0.052), as well as decreased disease-free survival, with a hazard ratio also of 0.74 ( p = 0.049).

A recent phase II trial for patients with residual disease or high-risk pCR after receiving neoadjuvant or postoperative anti-HER2 agents reported that the GP2 vaccine had no significant benefit in DFS in the total population, yet a subset analysis showed a trend toward improved DFS in the HER2+ group that received the GP2 vaccine ( p = 0.052) [ 46 ].

Testosterone levels were lower in male CRC patients (median 14.32) compared with healthy controls (median 17.69), with a trend toward significance ( p = 0.052; Mann–Whitney test).

A slight increase in plasma GFAP levels in ALS females compared to males almost reached statistical significance (179.43 (126.4–238) vs. 152.19 (110.4–231.9), p = 0.052).

One study observed that the levels of serum IL-6 in patients with alcohol dependence did not significantly decrease although they showed a trend from baseline to 16-week follow-up ( p = 0.052) [ 70 ].

Across the histological subtypes, the difference was almost significant ( p = 0.052), with nodular melanomas in particular showing high ENOX2 expression.

Generally, there was a strong trend for lower CS activity in SY5Y-APP695 cells compared to SY5Ymock cells ( p = 0.052).

For GR activity, the statistical analysis revealed a significant main effect for the group, which was almost significant (H = 5.655, p = 0.052).

We observed an almost significant reduction in neuroblast surveillance in the SGZ of male mice fed with n-3 PUFA-deficient diet ( p = 0.0521) compared to male mice fed with the balanced diet, as well as a trend toward reduction in the GCL of male mice compared to females ( p = 0.0594), both fed with the n-3 PUFA-deficient diet ( Figure 7 b).

The history of positive repeated TUR (re-TUR) (HR: 4.93, p -value = 0.0001) and T1 tumor stage (HR: 2.04, p -value = 0.0159) were associated with shorter RFS, while G3 tumor grade according to the 1973 WHO classification showed borderline significance (HR: 1.83, p -value = 0.0522).

The association between the SERP2 gene and the 0–6 h effect-site MEC was marginally significant (adjusted p = 0.05245; Supplementary Table S5 ).

A two-way ANOVA revealed a significant STRESS × PEPTIDE interaction for the time spent in the enclosed sector-2 and the percentage of entries in the enclosed sector-2 (F2,52 = 3.25; η2 = 0.12; p = 0.047 and F2,52 =3.42; η2 = 0.18; p = 0.042, respectively), and a marginally significant STRESS × PEPTIDE interaction for the enclosed sector-1 time (F2,52 = 3.12; η2 = 0.11; p = 0.053), without any significant main effects of the factors (F < 1.0; η2 < 0.02; p > 0.40).

Post hoc comparisons also revealed that J+A rats covered less distance in the open quadrants of the EZM compared to control ( p = 0.003), showed a borderline significant reduction compared to juvenile stress exposed (juv stress; p = 0.053), and showed a significant reduction compared to adult stress exposed rats (adult stress; p = 0.014) ( Figure 3 B).

The hsa-miR-155-3p target SP4 showed a trend for down-regulation (FC = 0.43, p = 0.053). 3.

Notably, when comparing ether-lipid-deficient mice against WT, wall stress at end-diastole was significantly increased at the septal wall ( Figure 3 C) and almost reached statistical significance for the free ventricle wall ( p = 0.053; Figure 3 D).

Among dietary and lifestyle variables, only flavonoid intake showed nominal interaction with GRS ( p = 0.037), while fat intake showed borderline significance ( p = 0.053); neither passed the Bonferroni correction.

Although the time course of left ventricular ejection fraction (LVEF) showed a trend toward reduction in the sham compared to the V-V ECMO group after the end of the experiments, the difference failed to reach statistical significance ( p = 0.053). 2.3.

Active smoking showed a trend towards increased risk (OR = 2.68, 95% CI: 0.99–7.28; p = 0.053), though this was not statistically significant.

Among the NTRs, there was a borderline significant difference (two-tailed independent t -test, p = 0.053, n = 6) in the level of p75NTR expression in the MOE with a higher level in vehicle-exposed TRPM5-GFP than in Skn-1a −/− mice, implying that TRPM5-MCs might, to some degree, modulate p75NTR expression.