Genome-Wide Association Study Identifies Genetic Polymorphisms Associated with Estimated Minimum Effective Concentration of Fentanyl in Patients Undergoing Laparoscopic-Assisted Colectomy.

Int J Mol Sci · 2023 · PMC10179231 · PMID 37176129

Europe PMC DOI

hedged sentences

0.0524

closest p · 1.0× alpha

0.0524

boldest claim

The sentences

marginally significantp = 0.05245so close (0.05 < p ≤ 0.1)

The association between the SERP2 gene and the 0–6 h effect-site MEC was marginally significant (adjusted p = 0.05245; Supplementary Table S5 ).

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highly significantno p-value reported

Among these, the rs966775 SNP that mapped to 5p13 had highly significant associations with 0–6 h plasma and 0–12 h effect-site MECs ( Table 1 and Table 2 ).

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