Excerpts

On the other hand, downregulation of CPS1 and TRIP6 protein in the low mRNA expression group was highly significant (Student ́s t -test; p < 0.01) in comparison to control ovarian tissues.

Accordingly, correlation analysis of the phototoxicity values obtained for the two PSs revealed a highly significant correlation ( p < 0.01; Pearson two-tailed correlation, data not shown). 2.1.2.

GIP levels were lower in male Tg 5xFAD/- and Tg 5xFAD/5xFAD mice compared to non-Tg, but changes did not reach statistical significance in Tg 5xFAD/- mice ( p = 0.010 and p < 0.05, respectively) ( Figure S2A ).

Statistical differences were designated as significant if p-values were less than 0.05 (* p ≤ 0.05), and highly significant if P-values were less than 0.01 (** p ≤ 0.01) or less than 0.001 (*** p ≤ 0.001).

Notably, cysteine and glycine displayed highly significant positive correlations with IL-6 ( p ≤ 0.01).

The differences were considered significant when p < 0.05 and extremely significant when p < 0.01.

Differences were considered significant at p < 0.05 and extremely significant at p < 0.01.

Differences were considered significant at p < 0.05 (*) and as highly significant at p ≤ 0.01 (**) and p ≤ 0.001 (***).

Mitochondrial Genes in the Liver The effect of the interaction diet × family was highly significant ( p < 0.01) on the expression of mitochondrial nd1 , cytb , cox1 , cox2 and atp6 genes in fish liver ( Table 1 ).

The differences between groups were considered as significant at p < 0.05 (“*”) or highly significant at p < 0.01 (“**”).

Comparison of the same developmental period in both pig breeds revealed extremely significant differences between groups ( p < 0.01), and it is noteworthy that the values of the parameters (the perimeter and area of the tubular lumen) in HZ boars were greater than those in LC boars in the 1 M, 3 M, 4 M, and 6 M groups, and stabilized in the 4 M, 6 M, and 8 M groups.

Significant differences were defined as p < 0.05 and extremely significant differences as p < 0.01, respectively.

A highly significant association ( p < 0.01) between 33 markers (25 SilicoDArT and 8 SNP) from this group and plant resistance to Leptosphaeria spp. was observed ( Table 1 ).

The results of a Student’s t -test showed a highly significant difference ( p < 0.01) between the sorption behavior of peanut protein to PCT at a nearly neutral pH of 6.8 and pH 5.5, even though the difference in pH was only 1.3.

As shown in Table 3 , the regression model was highly significant ( p < 0.01), and the out-of-fit term p = 0.1379 was not significant (confidence level of 95%), indicating a good fit of the model.

In the case of all tested strains, the combined use of antibiotics (AMC, AMP, and IMP) and phages (2e and 3e) resulted in a highly significant reduction in the number of resistant variants compared to those obtained after the use of either agent alone ( p ≤ 0.01 or lower).

BON-1 cells showed a highly significant ( p < 0.01) increase in caspase activity when treated with 20 or 5 μM LMK-235 for 24 and 32 h compared to the caspase activity at the time point of incubation ( Figure 2 A,B).

To determine whether PEMT expression decreased with increasing severity of hepatic fibrosis, we examined RNA-sequencing-derived expression data among different fibrosis stages, and observed a significant trend in decreasing PEMT levels with cirrhosis < incomplete cirrhosis < bridging fibrosis (β = −1.185; p = 0.011).

Between-group differences were not significant at baseline ( p = 0.22) but became highly significant from 24 h onward: 24 h (44.4% vs. 24.0%, p = 0.012, effect size = −1.00), 48 h (63.6% vs. 1.3%, p = 0.012, effect size = −1.00), and 72 h (83.6% vs. 2.1%, p = 0.008, effect size = −1.00). 2.4.

Due to a small variance, differences in the 3 wo group approached significance (t(4.5) = −4.10, p = 0.012, p adj = 0.059, d = −2.90 [−11.60, −1.68]).

faecalis at the end of the experiment were subjected to a Kruskal–Wallis analysis to confirm the higher presence in the butter-fed group of mice, and the difference was clearly significant ( p = 0.014), with post-hoc pairwise comparisons showing significance between BT and SD ( p = 0.025).

In those with tumor size > 10 cm, piR-823 exhibited a highly significant correlation with NANOG ( r = 0.451, p = 0.014).

EV Tg 330 kDa normalized to CD63 showed an increasing trend according to a differentiation score of the lesion (calculated according to histology and aggressiveness) ( Supplementary Figure S3 ; Spearman’s rho = 0.430, p = 0.014).

We observed a weakly significant upregulation in ahr2 (log2FC = 1.140; p = 0.015; FDR = 0.161).

Furthermore, overlapping with the age-stratified cohort (Corley et al., 2019), our PBMC signatures aligned strongly with the post mortem brain of the young cohort, such as in all ASD with 25 overlaps at a 76% consistency rate (hypergeometric p -value = 4.45 × 10 −15 , adjusted p -value = 5.34 × 10 −14 ), however, directional consistency across these age-stratified groups did not reach statistical significance (binomial p -value = 0.015 and adjusted p -value = 0.050) [ 28 ].