Barely Significant

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highly significantqualifiedgold
These SRGs, TCP1 (Chr 6), CCT2 (Chr 12), CCT3 (Chr 1), CCT4 (Chr 2), CCT8 (Chr 21), were found, in the overall GO enrichment analysis ( p < 0.01) of SRGs ( Supplementary Table S2 ) and contribute to a highly significant group of GO terms related to the telomeric region of chromosomes and to the Cajal body, including regulation of telomerase RNA localization to the Cajal body.
Given that, with the exception of the male gonads, most steroids in both sexes are synthesized either directly in the adrenal glands or from adrenal precursors in other peripheral tissues or directly in peripheral tissues [ 36 ], these results suggest an overall trend toward impaired adrenal activity in male patients with schizophrenia.
Steroidomics in Men with Schizophrenia.
Int J Mol Sci · 2024 · PMC11354902
While there is a significant trend towards lower levels of pregnanes (C21 steroids), as of 54 pregnanes, 31 levels are lower in patients, 20 levels are not significantly different, and 3 levels are higher compared to controls ( p < 0.001, Mann–Whitney test), for androstanes (C19 steroids), there is no significant trend, as of the 31
Steroidomics in Men with Schizophrenia.
Int J Mol Sci · 2024 · PMC11354902
Low-grade glioma showed a similar decreased survival trend with higher CD47 mRNA that approached significance at a mean cutoff ( Table 1 , Figure 2 c) and became significant with cutoff optimization ( Figure S1d ) or when median expression was used as a cutoff ( Figure S2c ).