Barely Significant

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highly significantqualifiedgold
The epigenetic modulation of Kiss1 or Kiss1r genes within the hypothalamus at puberty onset has been investigated in females, providing evidence that the methylation of both Kiss1 and Kiss1r genes promotes changes across puberty [ 41 ], with the development of highly significant puberty-specific differential promoter methylation patterns.
Finally, among the past 30-day adult e-cigarette users who were ever smokers, those who were former smokers were about one and a half times more likely (95%CI: 1.00, 2.12) to report using a non-tobacco flavor category or some flavor combination versus tobacco alone compared to current smokers, after adjustment, though this association was of borderline significance (see Table 4 ). 3.6.