Excerpts

The human life loss due to stock-outs of chemotherapy drugs that are used to treat CC is quite significant since efficacy of these regimens depends on taking a full dose per schedule for a required frequency of treatment cycles; this includes administering fewer cycles, delays in cycles or absence of any of the drugs which will reduce the curative potential to zero [ 22 ].

The negative tau-values represented a descending trend, while the positive value represented an increasing trend.

Among women, the between-study differences in trends of GO with age were highly significant.

As a developing country, China’s population aging has its unique characteristics [ 1 ]: a clear trend toward advanced aging, significant regional differences in the degree of aging, and a population aging that is incompatible with the level of socio-economic development and whose growth rate and proportion are above the world average.

Introduction Population Ageing has become a significant trend in global demographic change.

For example, parent history of psychopathology and children’s severity of internalizing symptoms were no longer significant predictors of the high ADHD probability/low SES latent class but approached significance (see Table 3 ).

Spatial Distribution Characteristics The RT villages in QTP showed a trend of aggregated distribution in space ( Figure 2 ).

However, in line with recent studies [ 7 , 11 , 19 ], an interesting trend did emerge that sees ELBW fathers showing high EPDS scores at 3 months, followed by a significant decrease at 9 months and by a stable trend till 12 months, while VLBW and FT fathers’ symptoms remained quite constant across all the first postpartum year.

The Pressure of Human Activities in 75.15% of China’s PAs Shows an Upward Trend In this study, the HAP in about three quarters of China’s PAs showed an increasing trend in the last 20 years, which indicates that human activities in and around the PAs are increasing.

(ii) The proportion of embodied energy of export in China’s energy consumption also showed a trend from growth to decline, standing at 26.57% according to the calculation results of the input–output table for 2018, which is higher than the proportion in 2002 but 4.91 percentage points lower than the 31.48% in the peak period of 2007.

Among the eight economic regions, the EWP of the northern coastal region, the eastern coastal region, and the southwest region showed an increasing trend.

Conclusions First, overall EWP in China showed a decreasing trend from 2006 to 2018.

However, the objective well-being effect also showed a trend of continuous improvement.

The importance level of slope (x2) showed a decreasing trend, exhibiting levels V, III, and II during 2005–2010, 2010–2015, and 2015–2019, respectively, suggesting that with the gradual adaptation of the ecosystem to the terrain, the impact of the terrain gradually decreases.

However, between 2009 and 2019, cultivated land, construction land, and facility agricultural land all showed a decreasing trend, while forest land and garden land types underwent increasing trends.

According to the summary and analysis by Huang [ 24 ], the current theoretical analysis generally believes that the fractured circle of uncoupled charge blasting is 10–15 r b , and with the increase in the uncoupling coefficient, the ratio of the fracture radius of the rock mass to the radius of the blasthole presents that there is a decreasing trend from fast to slow.

All the tests of significance were two-tailed with a p -value < 0.05 indicating a statistically significant difference and <0.001 showing a highly significant difference. 3.

australis communities increased significantly, but with the passage of years, these levels showed a trend of first rising and then declining [ 29 , 30 , 31 ].

Temporally, the CCD in all cities showed an increasing trend, but more than 60% of cities were still in the uncoordinated or low-level coordination stage.

We also found a decreasing trend in the GMI for the CCD in 2019, indicating inconsistent attitudes towards the implementation of greening layouts in neighboring cities under the backdrop of broader economic expansion.

From Figure 6 b, it can be seen that the percentage of landslides showed a trend of increasing and then decreasing, and landslides mostly occur in areas with lower slopes, mainly concentrated within 26 degrees.

Although not statistically significant, it is worth noting that the risk of an e-scooter-related injury was nearly twice as great for crashes that occurred on the sidewalk and the shoulder or vehicle lane of a neighborhood street, in reference to the bike lane (see Table 3 for the borderline significant results).

This pattern evolves at a relatively fast pace, with the association between symptom severity in individuals with PTSD and vmPFC lower fasciculus integrity already measurable and progressing two days after exposure to a highly significant traumatic experience [ 27 ].

First, the number of units in the moderately unbalanced category is the largest, accounting for 42.627%, 40.771%, and 40.105% in 2000, 2010, and 2020, respectively, showing a decreasing trend.

There was an increasing trend at the beginning of the experimental period; and there was a particularly sharp increase in phosphate concentration on the 70th day.