Excerpts

We performed Pearson correlation analysis of MP degradation gene profiles with genus-level microbes and selected highly significant and highly correlated (0.7 < |r| < 1, p < 0.05 ) relationships to demonstrate co-occurring networks, which indicated that microbes may be potential hosts for significantly enriched MP degradation gene profiles ( Figure 4 and Supplementary Table S2 ).

The third most abundant family was that of Myoviridae , exhibiting a decreasing trend ( post hoc Tukey test, p < 0.05) from surface (23% ± 5% relative abundance) to deep waters (14% ± 0.3%, Figure 3A ).

Relative to bare tailings, BSCs samples exhibited elevated concentrations of Fe, Cd, and Mn at both H and L groups, Zn at L group, and Al at H group, whereas Cu at H group showed a decreasing trend ( Supplementary Table S1 ; Tukey’s HSD, p < 0.05).

Compared to the CON group, TNF-α stimulation induced an increasing trend in the p-IKKα/β to IKKα/β ratio at 5 and 15 min ( P > 0.05; Figure 6 ).

Notably, co-treatment with SBC5-3 + TNF-α demonstrated a decreasing trend in the p-IKKα/β to IKKα/β ratio at 5 and 15 min ( P > 0.05).

Combined NMDS and MRPP analyses revealed a highly significant difference in community structure between the L group and the other two groups ( p < 0.05) (ANOSIM, p = 0.008 and 0.028; MRPP, p = 0.009 and 0.015; Table 6 ). 3.4 Functional predictions in the fecal microbiota of female donkeys across different reproductive cycles We used PICRUSt to predict the functions in the fecal microbiota of female donkeys across different reproductive cycles and evaluated the accuracy of these predictions using the Nearest Sequenced Taxon Index (NSTI) values.

Temperature had minimal impact on gut microbial functions at the gene level (KO) but became marginally significant at the pathway level (KEGG class level 3 and 2) (0.01 < p < 0.05, Figure 5c ).

During the 3-year period, the resistance rate to piperacillin-tazobactam initially declined but then increased ( p < 0.05), while resistance to ceftazidime-avibactam, aztreonam, imipenem, ciprofloxacin, levofloxacin, and amikacin showed a decreasing trend ( p < 0.05).

Parabacteroides was significantly correlated, positively, with TNF- α and IL-1β ( p < 0.05); Synergistota exhibited a significantly negative correlation with IL-6 and MDA, and a highly significant positive correlation with NO ( p < 0.05 or p < 0.01); Spirochaetota was significantly correlated, positively, with T-AOC, and significantly negatively correlated with MDA ( p < 0.01); Muribaculaceae showed a significantly negative correlation with IL-6 ( p < 0.05); Tannerellaceae had a significantl

Among them, the relative abundance of genera Fusobacterium (7.66%), Corynebacterium (6.43%), Rothia (5.71%), Bradyrhizobium (5.24%), and Brevundimonas (5.21%) were more than 5% in the duodenum and showed a decreasing trend from the duodenum to the rest of the intestinal sections ( p < 0.05).

Species differences in different groups The multiple groups’ significant difference test illustrated in Figure 4A reveals that Erysipelotrichaceae_UCG-003 , Lachnospiraceae_UCG-004 , Tyzzerella , and other genera, demonstrated statistically significant or highly significant differences in average relative abundance across the five groups ( p < 0.05, p < 0.01, p < 0.0001).

The high-dose group showed a highly significant suppression of VEGF, VEGFR1, VEGFR2, and HIF-1α expression ( p < 0.05 and p < 0.0001), with the medium dose also significantly reducing VEGF, VEGFR1, and HIF-1α levels ( p < 0.05 and p < 0.0001) ( Figure 7H ).

Specifically, there was an increasing trend in pH under the PTGM treatment from the initial soil pH in 2016 (pH 7.17), whereas pH changed slightly in PT ( p > 0.05) but decreased slightly in NT.

Effect of inoculation on plant biomass, relative effectiveness and crop yield Genotype (G) response was highly significant ( P < 0.05) at all harvests of 60, 80, and 120 DAS.

An increasing trend was also observed in the Chao1 richness estimates of HFI compared to HFC group (6274 ± 1299 vs. 4434 ± 1273; p = 0.0503).

Another isolate, D4T4, showed a trend of increasing ammonium production without nitrate addition (i.e., a probiotic treatment, p = 0.051).

Serum Biochemical Indices Birds in T group had an increasing trend ( P = 0.051) of serum IgY level with an elevated ( P < 0.05) serum IgM level at 3 DPI than those in PC group ( Table 4 ).

The effect of rice genotype was almost significant for all indices (Figure 1 , p = 0.051).

For ICU admission, the primary analysis showed a trend toward a lower probability of admission in the group of interest (OR = 0.39; 95% CI: 0.15–1.00; p = 0.051).

Dietary treatment also influenced the microbiota, showing a trend toward significance for Shannon diversity ( p = 0.051; Figures 2A , B ) and a significant effect on richness as estimated by Chao1 ( p = 0.038; Figures 2D , E ).

However, the near-significant reduction in phylogenetic diversity (PD whole tree, P = 0.051) hints at a potential loss of evolutionary complexity that warrants investigation in larger cohorts.

A further three genera approached significance for lower abundance in JFX, Prevotellaceae YAB2003 group ( p = 0.051), Colidextribacter ( p = 0.051) and Eubacterium cellulosolvens group ( p = 0.052).

plantarum PFM105 treatment showed a trend toward increased villus length over the antibiotic treatment ( P = 0.0518) in the ileum ( Table 2 ), while it had little effect on crypt depth and the ratio of villus to crypt in the ileum.

With Jaccard dissimilarity, the only significant variable or interaction was the interaction among biotype, host plant species, and host cultivar, although the interaction of biotype and host plant species was almost significant ( p = 0.052) ( Table 7 ).

However, we observed an increasing trend between smoking and the P metacommunity after clustering of the N metacommunities (chi-squared test, p = 0.052; Supplementary Figure 3B ).