Excerpts

This information was not recorded in the same way across the two cohorts (see methods), but a clear difference was apparent.

In that study, OCA2, KITLG, SLC24A4, and TPCN2, which are all associated with blond hair or blue eyes, did not show a nominally significant association with the risk of CM or BCC.

In contrast with a previous study [ 12 ], we did not find a significant interaction between sex and time of distress level 6 months apart, but only a small trend to a worsening in males.

Notably, secondary liver malignancies and concurrent exemestane use were associated with an increased risk of hepatitis, while the absence of anti-HBs antibodies showed a trend, though not statistically significant, toward increased HBVr risk, which may be due to small sample size and missing antiHBs titer data.

A clear trend towards more patients undergoing antileukemic therapy (2005–2011: 19% vs. 2012 and after: 71%) can be observed.

Cluster 3 ( Figure 3 A) showed an increasing trend in the pull-down from TK12-16, suggesting an increased activation of these proteins in all the sensitive cells.

Cluster 2, on the other hand, showed a trend of decreasing pull-down from TK12-16, i.e., also reduced in the most sensitive TK16 cell line ( Figure 3 A).

When all the proteins pulled down from ATX-101-treated cells were analysed in the same way as for untreated cells, we found only one cluster with a clear trend, i.e., an increase in the pull-down from TK12-16.

Our study showed a trend toward improving the LARS category from major to minor LARS, although, in a small number of patients, the improvement was insignificant, and these patients finally ended up needing permanent colostomy.

The raising awareness towards APL-like symptoms and the modern tools led to an increasing trend, over time, in the number of reports on new entities ( Figure 2 ).

Although the Kawaguchi system did not show strong predictive ability, a positive trend was evident, supported by a high Spearman coefficient.

Following this period, an increasing trend in reported cases of cardiotoxicity associated with various oncological agents has been observed.

Regarding OS, hemoglobin less than 120 g/L and age older than 70 years were significantly associated with shorter OS in univariate analysis, whereas Ki-67 > 30% in bone marrow, lymph nodes or other tissues showed a trend toward statistical significance.

This striking difference between the two groups was validated as highly significant by the statistical tests ( p value of χ 2 test was 0.007). 3.7.

Among patients categorized under density level B, the majority exhibited minimal BPE, while those in categories C and D showed progressively higher levels of BPE, indicating a clear trend correlating higher breast density with increased enhancement.

Kaplan–Meier survival curves comparing local recurrence-free, overall recurrence–free, and overall survival showed a trend toward improved outcomes in the 3D printing-guided group, although none of differences were significant ( Figure 3 ). 4.

The results suggest a possible trend of an association favoring BED ≥ 100 in improving surgical resectability, highlighting the potential impact of ablative-dose SBRT in enhancing surgical outcomes for BRPC and LAPC previously considered unresectable.

45%), with a nonsignificant trend towards improved response rates [ 61 ].

p -values < 0.05 were regarded as the statistical difference, and p < 0.01 was viewed as highly significant. 3.

The HRF framework achieved an average C-index of 0.79 ± 0.08, while the DRF framework showed a slightly higher C-index of 0.80 ± 0.1, both with highly significant log rank p -values below 0.001.

Patients who achieved CR to glofitamab also showed a trend toward a higher percentage of CD8+ T-cell infiltration in the TME [ 49 , 51 ].

Two of the analyzed studies [ 28 , 29 ] and PNCR data [ 8 ] consistently pointed to an increasing trend in the incidence of bladder cancer in Poland from 1980 to 2013.

Even though the greatest impact of HPV-associated diseases is related to cervical cancer, an increasing trend is registered for head-neck and anogenital cancers [ 2 , 3 ].

There is an increasing trend towards robot-assisted prostatectomy in numerous countries.

In addition to peer-reviewed articles, a grey literature search was conducted using Google to identify preprints and unpublished studies with substantial data, specifically non-peer-reviewed evidence, such as government reports, organizational white papers, or preprint studies, which may be significant in the rapidly evolving field of AI in healthcare.