Excerpts

Introduction Thyroid cancer is the most common endocrine cancer, and its incidence has shown an increasing trend over time.

Kaplan-Meier curves showed a trend toward lower RNF5 expression in patients with poor prognosis, which, however, was not significant ( p > 0.05) ( Figure 1 d).

Additionally, a marginally significant increase in CD8 expression was observed.

When analyzing normal oral mucosa, a highly significant and strong positive correlation between CD80 and CD86 expression was seen.

There was a statistical trend towards higher rates of suboptimal cytoreduction in older women, where 57% of women younger than 54 years had complete cytoreduction to no macroscopic residual disease, 33% had optimal cytoreduction to macroscopic residual disease ≤ 1 cm, and 10% had suboptimal cytoreduction with macroscopic disease > 1 cm.

The time-activity curve shows a decreasing trend with a peak at 69 h.

We detected a strong trend for the reduced proliferation of the PDGFRɑ+ cells in tumors from pl-PDGFB KO mice, although not statistically significant at this time point ( Figure S3A ).

Second, the data regarding EBV status were missing in one-quarter of the patients, resulting in a nearly significant discrepancy in KTR and LTR group composition.

High a-SMA and TAGLN gene expression only showed a trend suggesting an association with severe prognosis ( Table 1 ).

One study showed a trend toward better preservation of hearing after FPT, reducing the total dosage from 54 to 50.4 Gy (RBE) [ 30 ].

HR-NBL1 study patients (R2 and R4 combined) who were not in complete remission (non-CR) before immunotherapy showed a trend towards a higher incidence of severe neurotoxicity (patients with severe neurotoxicity: 86% non-CR vs. 15% CR, patients without neurotoxicity: 55% non-CR vs. 45% CR; p = 0.0628; Fishers exact test).

A positive trend seen in our TGF-β gene expression data could thus be further amplified by the genetic ablation or pharmacological inhibition of TGF-β signaling.

As we expected, an increasing trend of LTα, LTβ, and LTβR could be found in the HPV-positive OSCCs when compared to the HPV-negative group ( Figure 4 A).

In U251-MG R cells, we observed a decreased number of colonies and a clear trend in decreasing colony numbers between treatments, although there was no statistical significance ( Supplementary Figure S5B ).

In the literature there is also some evidence that in order to differentiate ULMS, adenomyosis and ULM, the evaluation of the endo/myometrial junctional zone may be significant, especially the vascular pattern between these two types of tissue, as was suggested by Fascilla et al.

Despite that the primary endpoint was not significant, OS in the RT arm for patients with low M1 burden (<5 bone metastases) showed a trend favouring RT.

The number of articles about cancer biosensors and antibody mimetic molecules had an increasing trend from 2004 to 2018, recombinant antibodies from 2014 to 2017, and molecularly imprinted polymers from 2013 to 2016.

Concordant association for GBC was of borderline significance (2.14) but the discordant association with cancer of the extrahepatic bile ducts (3.71) was significant.

A favorable trend in PFS was observed in the V600E population, although without reaching statistical significance.

The intervention group also had significantly fewer visits to the emergency room and an observed trend toward fewer hospitalizations [ 16 ]. 3.

However, even extracapsular nodal spread and RT administration showed a clear trend towards significance as adverse and protective factors, respectively [ 27 ]. 3.1.3.

Of the five quantitative studies assessing marital status as a determinant of change in smoking behavior [ 52 , 53 , 59 , 93 , 95 ], one found a marginally significant association between marital status and changes in smoking behavior, with married participants yielding higher abstinence rates in the intervention group [ 59 ].

Of the six quantitative studies that assessed stages of change , four found a statistical significant association between a higher stage of change and favorable lifestyle changes, mostly in smoking behavior [ 53 , 55 , 58 , 76 ], and one found a borderline significant association [ 54 ].

However, although pre-existing immunity towards the HLA-A2 restricted epitope correlated with longer PFS, high pre-existing and vaccine-induced immunity towards the HLA-A2 restricted epitope showed a trend towards a shorter PFS.

Patients with single metastasis had a significantly better prognosis than those with multiple metastases, and even showed a trend toward better survival than those with oligometastases.