Excerpts

found only a weakly significant increase in the risk of VSCC for women reporting a history of abortion [ 79 ].

The estimates showed a trend towards an increased rate throughout the entire follow-up period ( Table 4 ).

As a result, BD was not a significant risk factor for LNM in our study despite borderline significance.

With increasing tumor size, the IL-7R level exhibited a decreasing trend ( Figure 3 E) and the CA19-9 level showed an increasing trend ( Figure 3 F).

Excisions per year ranged from 3411 to 4749, with a clear trend towards increasing numbers of melanoma from 2014; the average number of melanoma/year prior to and following 2014 doubled (200 vs. 410).

In 2020, the second meta-analysis only focused on stages IB2 and II cervical cancers and was thus limited to 5 studies, including 2 case–control studies and only 1275 patients, with a nonsignificant trend for a 40% reduction in the risk of death with neoadjuvant chemotherapy [ 50 ].

Furthermore, patients treated with a combination of PD1 inhibitors and chemotherapy showed a trend to a better response than those treated only with chemotherapy, underlining the potential synergy among the two treatments [ 16 ].

Patients with stage T2 tumors who received a PTVmax ≥ 125 Gy (BED 10 ) showed a trend toward improved LC, yet there were no significant differences in comparison with those who received a PTVmax < 125 Gy (BED 10 ).

[ 20 ] looked at the mean annual hours of bright sunlight in Australia, finding a significant trend of ORs in CM risk with more hours among native-born Australians (so longer exposure) and a reduction among migrants; however, the adjustment for sun sensitivity was unclear.

Despite this, a statistical trend towards higher levels of 17 kDa cleaved-Caspase-3 was found in the LF-HEVOO group.

A slight trend towards an increase in the G 1 population of the MV4-11 cells (16% increment) was noted after incubation with 0.3 μM CDDD11-8 for 24 h ( Figure 2 C).

For F98 rat GBMs, the SSM and 2CXM models demonstrated an increasing trend in the percentage of necrotic pixels due to JAS239 treatment from T3 to T8 compared to control animals ( Figure 3 A).

A large cohort study showed a trend for TP53 mutations in predicting a worse OS of EGFR -mutated patients receiving targeted therapy with respect to wt TP53 patients (2.9 years vs.

Maximal OCR showed a trend lower only in metformin.

showed a nonsignificant trend towards improved overall survival for adjuvant therapy (radiotherapy, chemotherapy, or both) in comparison to surgery without adjuvant therapy for patients with biliary tract cancers, including GBC (odds ratio [OR] 0.74; 95% CI, 0.55–1.01; p = 0.06) [ 86 ].

Indeed, a positive trend toward a better QoL was observed within patients receiving trifluridine/tipiracil [ 46 ].

The PERCIST criteria ( p = 0.059) showed marginally significant association with PFS.

p -values under 0.05 were considered significant and p -values between 0.05–0.1 were considered to indicate a statistical trend.

This is particularly relevant as there is an increasing trend towards a neoadjuvant therapy approach in breast cancer as highlighted elsewhere in this paper.

Similarly, median PFS for the last anti-EGFR-based therapy showed a trend towards a shorter mPFS in the rechallenge patients compared to the reintroduction patients without statistical significance (3.68 vs. 7.33 months, n.s.). 4.

Introduction Thyroid cancer is the most common endocrine cancer, and its incidence has shown an increasing trend over time.

Kaplan-Meier curves showed a trend toward lower RNF5 expression in patients with poor prognosis, which, however, was not significant ( p > 0.05) ( Figure 1 d).

We detected a strong trend for the reduced proliferation of the PDGFRɑ+ cells in tumors from pl-PDGFB KO mice, although not statistically significant at this time point ( Figure S3A ).

Second, the data regarding EBV status were missing in one-quarter of the patients, resulting in a nearly significant discrepancy in KTR and LTR group composition.

High a-SMA and TAGLN gene expression only showed a trend suggesting an association with severe prognosis ( Table 1 ).