“trending toward significance”

Although only trending toward significance, likely due to the low number of patients in this subgroup analysis, these data suggest that there may be a clinically meaningful benefit from the IO score or the IO + /TMB high model (IO HR 0.3001, 95%CI 0.0773–1.165, p = 0.0819; IO + /TMB high HR 0.3432, 95%CI 0.09792–1.203, p = 0.0946) (Figure S2A).

ALT levels were decreased in both groups from 25.1 to 22.9 U\L in the statin group, with a p -value of 0.09 trending toward significance, and from 27.2 to 25.2 U\L in the no statin group.

There was also no statistically significant difference in mean concentrations of 0.30 to 0.90 μm aerosols ( F [2, 436] = 2.49, P = .09) or 0.90 to 2.69 μm aerosols ( H (2) = 5.74, P = .06), though the latter was trending toward significance.

Although trending toward significance, the effects were opposite of these seen for sorting based on formant differences: in separate Condition analyses, Intensity had a non-significant effect on N1 during Talk ( F 2,196 = 1.67, p = .190) but a significant effect during Playback ( F 2,196 = 3.23, p = .042) such that louder sounds elicited larger N1 components.

Consistent with this notion, the strict obligate anaerobic genera Anaeroplasma and Lachnospiraceae XPB1014 group appeared elevated in INF sow vaginal microbiota, with Anaeroplasma trending toward significance and Lachnospiraceae XPB1014 group exhibiting a significant increase.

Like hearing loss, worsening SIOP grade was associated with age (p <0.0001), radiation to any part of the body (p=0.023), and amount of CDDP per dose (p=0.037) on multivariate analysis, with cumulative dosing trending toward significance (0.057) ( Table 3 ).

P values trending toward significance and pertinent nonsignificant are indicated on the graphs.

Treatment effects were analyzed by using a ratio-paired Student’s t -test, with p < 0.05 being significant and p < 0.1 reported as trending toward significance (28) .

The PIT asymmetry scores indicated greater asymmetry of plantar flexor and dorsi flexor muscle torque in PwMS than healthy subjects, with the knee extensors and flexors trending toward significance.

In addition, there was progressive upregulation of immune checkpoint proteins, including PD-1 on day 63 ( P = 0.019) and day 112 ( P = 0.040) and LAG3 on day 63 ( P = 0.086) and day 112 ( P = 0.086) that was trending toward significance ( Figure 2 b).

Statistical significance was set at p ≤ 0.004 significant, and 0.05 > p > 0.004 trending toward significance.

4 , 44 – 47 In our own study, we found improvement in arc of motion, with palmar abduction and PIP arc of motion reaching statistical significance, and radial abduction trending toward significance.

However, by the third repetition, the difference had substantially vanished, with one item trending toward significance and no item achieving significance.

Responses were slower during the biological night at 4 hours post-dim light melatonin onset (P adj <0.01), and trending toward significance at 8 hours post-dim light melatonin onset (P adj = 0.06).

Significant correlations included relationships between the CKCUEST and dominant IR and dominant and non-dominant ER strength, with non-dominant IR strength trending toward significance.

Importantly, patients in Cluster 2 also had more adverse clinical features, including higher Ann Arbor stage and IPI, with elevated LDH levels trending toward significance.

We recommend further investigations in a multicenter study with a larger sample size to explore the different variables that were not statistically significant but trending toward significance.

A third of the studies with SD rats do not include an experimental group with a single exposure, and another 33% cite that no cumulative effect was observed, with results trending toward significance.

INR was correlated with age and was trending toward significance for ethnicity (see section Demographic Variables).

Moreover, although Ym1 expression was not significantly altered in either condition, its downregulation was trending toward significance with combined treatment ( Figure 6D ).

While relatively modest in magnitude and in general, trending toward significance, it is noteworthy that reductions were observed across several different threat-related paradigms.

FHR-3 levels were also trending toward significance, indicating that a minor difference in the copy number variation in CFHR3/CFHR1 between the two cohorts might be affecting the results ( 33 , 35 ).

To better examine this idea, sensitivity analyses (Table S3 ) revealed that baseline cognitive performance was stronger (significantly or trending toward significance) across measures for EOAD participants who remained at later visits than those who discontinued.

In addition, nilotinib treatment reduced HIF1α protein levels after alcohol treatment in a manner trending toward significance ( Figure 10 G and H ).

This smartphone use pattern was paired with psychosocial risk factors that were predominantly lower than respective scores for Profiles 2 and 3, but with protective factors, that is, social support variables, only trending toward significance or not being significantly different from Profiles 2 and 3.