“trend toward significance”

Outcomes of PELD versus OLM yielded slight trend toward significance favoring OLM with an OR = 0.50 (95% CI0.21-1.16), P = .10.

In another study demonstrating the efficacy of ustekinumab to reduce cardiovascular risk, the trend toward significance reduction in IL-17A and IL-23 could be seen at 12 weeks ( p < 0.1) from initiation of therapy, and a more significant reduction in these was achieved at week 52 [ 24 ].

Some p values that may trend toward significance ( p < 0.1) are also indicated.

The significance level for detecting differences among methods was set at P < 0.05, and the trend toward significance was 0.05 ≤ P ≤ 0.10.

A binary logistic regression analysis was conducted with age, sex, and variables with significance (p<0.05) or trend toward significance (p<0.10) on univariate analyses with response as an independent variable (i.e., responders and non-responders).

For OS, only FIGO stage was significantly predictive; among the other clinical parameters, LipB mRNA expression levels exhibited the highest trend toward significance (p = 0.103, Table 4 ).

The trend toward significance ( P = 0.126) of target attainment in the univariate analysis did not translate in the multivariate analysis.

Here, as in the digit span forward test, a limited trend toward significance was observed for the high-dose group (Fig. 3C2 , #P = 0.1324).

Regarding DFS, neither clinical parameters nor sHE4 levels were indicative of disease recurrence, even if elevated sHE4 levels exhibited the highest trend toward significance ( P =0.14 and P =0.17, Table 4A ).

Reductions in alcohol use trend toward significance at the post-intervention time point ( β = −0.23, p = .15) achieving statistically significant reductions ( β = −0.56 p = .01) for the FSI-HIV compared to controls at three months ( Figure 3 (a)).

The 2 treatment factors with the closest trend toward significance were use of IMRT (β = −0.0001 [95% CI, −0.0007 to 0.0001]; P = .17) (eFigure 11A in Supplement 1 ) and neck dissection (β = −0.0003 [95% CI, −0.0007 to 0.0001]; P = .11) (eFigure 11B in Supplement 1 ), both of which appeared to correlate with lower rates of CNF.

For specific DDR pathways, the difference of CCF increase was significant in the Fanconi anemia pathway ( P = 0.007) and showed trend toward significance in HRR pathway ( P = 0.18) ( Figure 1D ).

The trend toward significance seen on longitudinal analysis was not observed on post-hoc analysis (M24 compared to M0, p > 0.23).

Multivariate analysis was used in factors that were significant (p < 0.05) or exhibited a non-significant trend toward significance (p < 0.25) on univariate analysis.

Of course, it still remains to be determined whether de novo variants (particularly de novo LGD variants) carry risk in multiplex families, as the effects observed here trend toward significance (e.g., RR 1.16; p = 0.26 for de novo LGD variants) in an under-powered analysis (103 multiplex trios) and de novo variants appear to carry risk in multiplex families for other neurodevelopmental disorders ( Leppa et al., 2016 ; Martin et al., 2017 ).

The results are shown in Table 6 which show that the MMSE is clearly the strongest predictor of the CDR, followed by total ICV and the anterior callosal compartment (H&F1) which both trend toward significance.

When p values between .05 and .10 were obtained, although nonsignificant, we considered that this suggested a likelihood or trend toward significance.

There was also trend toward significance for current smoker (AOR, 0.32; 95% CI, 0.10–1.00).

Incubation with TMI005 prevented LPS and poly I:C induced reduction of cells in the intermediate monocyte gate, with a similar trend toward significance for flagellin ( ns = not statistically significant).

Here again, this trend toward significance was not seen when excluding those pregnancies that had a BW:PW ratio outside the 10th and 90th centiles (a total of 8 data points).

This partial overlap is a common feature of QMI data; due to the stringency of the statistical analysis, many interactions that are identified as “significant” in one experiment may only trend toward significance in the next (Heavner et al. 2021 ).

This clinic had the highest rates of barriers to social determinants of health, suggesting that clinic factors could have contributed to the trend toward significance of ADI for those screened as likely cognitively impaired.

For example, larger sample sizes would improve the interpretability of matched pairs analyses, as some current findings trend toward significance.

Notably, this decrease is preceded by an early increase, detected at day 3 of culture, in RSV-treated and T EMRA D-derived T EMRA CD8 + (trend toward significance) and CD4 + T cells in the T EMRA E presence of T EMRA E ( Figure 6 F).

A selective trend toward significance among phenotypic mutations is also observed for A→C/T→G (sense/antisense) among phenotypic mutations, and for G→A/C→T (sense/antisense) among both phenotypic and incidental mutations (Table 5 ).