Three independent clumps were suggestive of significance in the 6-month follow-up analysis ( Table 2 and Fig. 3 ), with no evidence of inflation (lambda = 1.02, Fig. 4 ).
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“suggestive of significance”
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It amounts to 66.7% when compared with 14.7% in babies weighing 2.5 to 3.5 kgs which is suggestive of significance ('P' value of 0.093).
All SNP p-values remained suggestive of significance.
Probes with a Benjamini-Hochberg-adjusted p-value less than 0.05 were considered significant and adjusted p-values less than 0.1 were considered suggestive of significance.
Additionally, we considered p-values falling between 6.84E−05 and 0.05 suggestive of significance.
Unless specified otherwise, p < 0.025 (0.05/2 databases) was used as a significance level after Bonferroni correction to account for multiple testing, with a 0.025 ≤ p < 0.05 being considered suggestive of significance.
SNPs that showed an association at P < 1.0 × 10 −5 (suggestive of significance) were selected for independent validation.
Statistical analysis In IVW analysis, a P value less than 0.05 is considered suggestive of significance, while a P FDR < 0.05 is deemed statistically significant.
The genome scan identified two regions with LOD > 1.88, the threshold suggestive of significance ( Fig. 2 , Table 2 ).
The significance threshold is p < .005, considering that many association studies for a single test changed the p value from .05 to .005, and the results with p values between .05 and .005 were considered to be suggestive of significance.
Additionally, a p-value < 0.05 was considered suggestive of significance [ 49 ].
For multiple tests, associations with p -values < 0.0021 were considered statistically significant, while p -values ≥ 0.0021 and < 0.05 were regarded as suggestive of significance.
No individual genetic variants were identified at conventional levels of significance in any analysis although several loci were associated at a level suggestive of significance.
P-values between 0.05 and 0.0056 were considered suggestive of significance.
Two-tailed p value < 0.05 was considered suggestive of significance.
After correction for tests on 3 exposures, associations with P values of <0.017 (0.05/3) were considered statistically significant; P values between 0.017 and <0.05 were considered to be suggestive of significance.
Exploring other associations suggestive of significance reveals several interesting findings, including SNPs in SP110 associated with both lean mass and WC, and WARS2 , associated with HC and WHR.
Using the Bonferroni‐corrected threshold of p , p < .017 ( α = .05/3) was considered significant in our study, and p between .017 and .05 was considered suggestive of significance.
p < 0.005 was considered significant, and p < 0.05 as suggestive of significance. 3.
Generally, a p value ≤ 0.10 for the Cochran's Q test or an I 2 ≥ 50% was suggestive of significance among-study heterogeneity [ 34 ].
Importantly, this effect was only seen as suggestive of significance in the LAI adjusted GWAS, suggesting the need for LA adjustment in GWAS of admixed populations such as Caribbean Hispanics.
A p -value of statistical significance after Bonferroni correction was 0.0083 ( α = 0.05/6), and p -values between 0.05 and 0.0083 were considered to be suggestive of significance for UVMR results.
p values between 0.000350 and 0.05 were considered to be suggestive of significance. 2.4.
P values between P < 5.38 × 10 −6 and 0.05 were considered suggestive of significance [ 20 , 21 ].
All identified SNPs that reached significance or seemed to be suggestive of significance were visualised using Haploview software [55] .