When stratified by EGFR mutation status, immunotherapy was associated with significantly longer OS in the EGFR wild-type subgroup ( p = 0.004) and showed a trend toward improved OS in the EGFR-mutant subgroup ( p = 0.05) (Supplementary Fig.
Family communication satisfaction regarding the illness showed a trend toward near significance (p>0.05), with HD patients being more satisfied (mean=2.1, SD=1.2).
However, compared to the mono-group, the combo-group showed a trend toward earlier resolution of fever (p = 0.05 on day 2 and p = 0.06 on day 5, Table 2 ).
Physical examination of patients revealed crackles in 8.2% (n = 82) and showed a trend of its presence in patients with persistent post-COVID-19 symptoms (9.9% vs. 5.8%, p = 0.05).
of day, F (7.957, 453.568) = 13.392, p < 0.0001; Main effect of day × genotype, F (15.915, 453.568) = 1.239, p > 0.05; Main effect of day × cre, F (7.957, 453.568) = 1.078, p > 0.05; Main effect of day × genotype × cre, F (15.915, 453.568) = 0.672, p > 0.05), where average distance traveled showed a trend toward increase in HOM Cre+ compared with WT Cre+ and WT Cre− controls (Figure S5D : Two‐way independent ANOVA: Main effect of genotype, F (2, 57) = 3.538, p < 0.05; Main effect of cre, F (1, 57) = 1.204, p > 0.05; Main effect of genotype × cre, F (2, 57) = 0.736, p > 0.05; Bonferroni: WT Cre− vs.
Histological analysis of activated Caspase 3, a marker of early apoptosis, indicated no significant changes in sub‐endocardial apoptosis (Figure S2 A and C), although the apoptotic effect of DS‐induced hypertension showed a trend ( P = .05; Table S9 ).
Limited Nesting Stress from Post-natal Days 2–10 Increased Plasma Corticosterone Levels in Pups at Weaning In PND21 males, plasma corticosterone values showed a trend to be higher in LNS group compared to CTL which did not reach statistical significance (4.0 ± 0.4 μg/dL vs 2.4 ± 0.7 μg/dL, P = 0.050, n = 8–9) ( Fig. 1A ).
Both NPs + Probiotics 10 9 CFU and NPs + Probiotics 10 10 CFU groups showed a trend toward reduced MDA levels compared to NPs alone (p < 0.05).
The reduction in fetal body weight in the progesterone-reduced group at 21 dg did not reach statistical significance (p=0.07) but showed a trend to reduce (Mann-Kendall test; correlation=0.8, p=0.05).
In addition, has-miR-181c and has-miR-10a showed a trend towards higher expression levels in DCM samples ( P > 0.05).
From 1990 to 2019, in the gender group, only the rate and incidence of DALYs in the whole population showed a trend change with years ( p < 0.05), and the disease burden of males showed a trend change with years ( p < 0.05), while the disease burden of females did not ( p > 0.05) (Table 3 ).
2 b, with the increase of the nozzle printing height, 3D printing accuracy and stability of shrimp surimi both showed a trend of first increasing and then decreasing ( P < 0.05).
Microglial depletion caused a slight, but not significant, decrease in GFAP intensity in wild-type mice, and PLX-treated ATXN1[82Q] mice showed a trend toward a decrease in GFAP expression (Fig. 4b , one-way ANOVA, p > 0.05).
There was no difference among the three groups in either right- or left-sided ADR, although the AI and pre-AI groups showed a trend toward an increased right-sided ADR ( p =0.05).
Additionally, the TC, TG, LDL-C and HDL-C concentrations in the ε4 carrier control participants showed a trend towards higher levels compared to the DN group (all p > 0.05).
Re-analysis of our past metabolomic data showed a trend for lower lactate in liver (p=0.05), fat (p=0.06), and serum (p=0.08) of IVF5%O 2 conceived mice compared to control ( Feuer et al., 2014a ; Figure 7—figure supplement 1 ).
Although treatment with GLS or GLF showed a trend reducing the tumor multiplicity ( Fig 2C ) ( P > 0.05), their tumor incidence data overlap with the UV only group ( Fig 2B ).
The volume of total adipose tissue showed a trend to be lower in patients of the progression/death during follow-up group (Mann–Whitney U test, W = 1279, p = 0.05).
In HA-stimulated cells, several pathways potentially related to ERK signaling, including the calcium signaling pathway and glycerol phospholipid metabolism, showed a trend toward enrichment (nominal P -values <0.05), although they did not pass the predefined FDR threshold ( q -value <0.25) ( Supplementary Table S4 ).
The verification results of ABHD 8, DHPS, ISOC2 and MRPL34 were consistent at the transcriptome level and qRT-PCR At the transcriptional level, 6 diagnostic genes were significantly different between normal and BC groups, The expression levels of ABHD8, DHPS, ISOC2, MRPL34 were significantly upregulated in the tumor group compared to the normal group, ESRRA and OGFR also showed a trend of high expression in the tumor group ( p < 0.05) (Fig. 8 A).
2B ) showed a trend for shorter BCR with a median of 91 months (95% CI not computed) compared to 125 (111.5–158.5 months) in patients with low SOAT2 staining ( n = 247, Log rank p = 0.05).
Besides, the R -value of soleus, gastrocnemius, and hamstring muscle decreased ( p < 0.05), and the results showed a trend of shortening MEP latency, increasing amplitude and duration ( p < 0.05).
The group supplemented with Astragalus dregs showed a trend towards improved ADG and ADFI and reduced diarrhoea rates ( p > 0.05).
Kaplan-Meier analysis also showed a trend of improved survival in mice treated with pevonedistat alone and in combination over the control group (p < 0.05) (Figure 6C ).
We failed to identify significant differences in the APRs expression according to the use of treatment. Associations between acute phase reactants gene expression and their plasma concentrations Plasma CRP showed a trend toward higher levels in COPD patients (4.4±1.73 mg/mL) than in control group (3.8±2.04 mg/mL, P >0.05).