Importantly, data of the 320 mg group showed a trend of superior anti-HIV activity to that of the 160 mg group.
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The modulation of TFAM expression, TFAM-binding to mtDNA and mtDNA content with aging and CR showed a trend shared by the skeletal muscle and liver, but not by the frontal cortex counterpart.
Expression of Tgfb1 , a pro-fibrotic growth factor, showed a trend of increasing in the IU+ group, whereas mRNA for Il6 , a cytokine implicated in NAFLD, showed a trend of increasing in the IU group.
Phenotypic primitive cells were increased in 126OE groups for seven of nine samples ( Figure 4 A) with concomitant reduction of differentiated cells; four of nine samples showed a significant reduction for CD15 + cells ( Figure 4 B), and six of nine showed a trend for reduced CD14 + blasts ( Figure S4 E). 126OE caused an increase in CD15 + blasts for two samples ( Figure 4 B).
3b ) leachates showed a trend to decrease through time, and fluctuated before reaching a stable concentration in oak leachates (Fig. 3d ).
The results of the study showed a trend towards cognitive impairment in the control group and an opposite tendency of mice treated with Aβ1-6 A2V TAT(D), whose cognitive performances were no worse than at the beginning of the treatment with Aβ1-6 A2V TAT(D).
The general time–concentration profile of UCHI3L1 showed a trend for increasing concentrations from 24 h before, towards diagnosis of the first episode of AKI SCr/UO stage ≥2 (reference time 0 h; Fig. 3 ).
Lipid profile in different variants LDL and HDL levels showed a trend of decrease in the heterozygote form of Rs.2278426, which was not statistically significant.
The corresponding OR of failure of SLNM showed a trend with 3.8, but Chi-Square test did not reach statistical significance in this subset of patients (p = 0.09).
Principal component analysis (PCA) was performed on the dataset, which showed a trend of intergroup separation on the scores plot (figures not provided).
Behaviorally, early bilinguals performed similar to natives (data from Díaz et al., 2011 ) in all sentence types, although they showed a trend toward poorer performance in the object-verb agreement violations.
1a ) plus fluorouracil/leucovorin (FOLFOX4) as palliative chemotherapy in HCC patients from Asia found that this regimen showed a trend toward improved overall survival, along with increased progression-free survival, although the primary end point was not met 6 .
Rats receiving BM-MSCs showed a trend toward lower lung wet-to-dry ratio at 24 h.
was shown to exist between RAGE expression and microvessel density in human endometrial cancer samples; (iii) RAGE knockdown was effective in decreasing microvessel density in xenografted tumour models; and (iv) Kaplan-Meier analysis and log-rank tests for overall survival revealed that RAGE levels showed a trend for poor overall survival (Additional file 2 ), but no significant difference was observed ( P = 0.167).
A higher body mass index showed a trend toward predicting a higher mode dose of paliperidone ER.
Trait dissociation showed a trend for a relationship in the same direction.
DISCUSSION Despite for several years the benefit of varicocele treatment has not been clear, a recent meta-analysis of four randomized controlled trials of varicocelectomy in men with a clinical varicocele and semen parameters impairment showed a trend in favor of surgical correction. 9 Varicocele treatment as demonstrated in a randomized controlled trial showed superiority over observation in infertile men with palpable varicoceles and impaired semen quality, with increasing the odds of natural pregnancy and improvements in semen characteristics
Subsequently, a Wilcoxon rank sum test was applied to assess whether the contrasts associated with each class showed a trend towards high or low expression level within the ranked microarrays.
A high (i.e., above the median of 31 cells/mm 2 ) number of TCL1A + CD19 + cells showed a trend towards improved survival, similar to the correlation for the total number of TCL1A + cells (see Figure 4C ).
An analogous behavior was found in the light/dark test, where the entries and the time spent in the aversive lit compartment showed a trend towards being reduced in AAV-Glu-MAGL, though without reaching statistical significance (time in lit compartment P =.133, unpaired t test; Figure 5E ; entries in lit compartment P =.060, unpaired t test; Figure 5F ).
The nevi around the primary melanoma showed a trend for less immunoreactivity to p-ERK than the primary melanoma within the same nevus although it was not significant (p = 0.0856). p-ERK immunoreactivity in melanoma metastasis was significantly stronger than in melanocytic nevi (p < 0.0001), CMN (p = 0.0052), primary melanoma (p = 0.0388) and the associated melanocytic nevus (p = 0.0017) (fig. 1g ).
In our initial observations with a small number of mice, we had observed that VEGF‐A hyper mice lacking Il18 showed a trend toward having more CNV lesions, but the observed high variability within this group of mice and the small sample number resulted in statistically inconclusive results (Marneros, 2013 ).
Analysis of the epithelium thickness showed a trend for a thicker layer in the ADSC group comparatively to the control group.
Specifically, although AstroEGFR*1, which reached overexpression levels comparable to those in AstroEGFR*2, showed a trend of extended survival that did not reach statistical significance, AstroEGFR*3, despite much stronger Zfp423 overexpression, displayed a shorter survival.
The combination treatment group had significantly better long-term survival rates than the RFA group, and showed a trend favoring an OS benefit compared to the TACE group; however, significant differences between the RFA and TACE groups were not observed ( p = 0.044, p = 0.046, and p = 0.771, respectively, based on log-rank test) ( Fig. 3 ).