Mice treated with low dose MMC (for 60 or 90 min) showed a trend to a reduction in tumor volume compared to saline controls (60 min; 1480±352 mm 3 , n=15; 90 min; 1252±318 mm 3 , n=15).
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A second contemporaneous study, D9902A, in which enrollment was 44 discontinued early (N = 98), showed a trend towards improved survival, which did not reach statistical 45 significance.The treatment effect remained strong after performing adjustments for imbalances in baseline prognostic factors, post study treatment chemotherapy use, and non-prostate cancer-related deaths and suggested a favorable risk-benefit ratio for sipuleucel-T in patients with advanced prostate cancer [ 23 ].
Lambs gavage with a single bolus of 2.27 g OVA (Group A) showed a trend towards decreased antibody production relative to the parenteral control group after 7 weeks but the difference was not statistically significant (Figure 1 D).
Additionally, all 5 genes appeared to exhibit a trend of altered expression at an early age, at least by 5 months; furthermore, NDUFA5 showed a trend of progressive dysregulation with age.
The weight showed a trend to recover to the initial level (Pre) during the reloading period.
However, C1 INH treated rats showed a trend for reduction of MPO-positive cells ( Figure 8A, B ).
The content change of total anthocyanin in Ginkgo showed a trend of first rise in the stable and then drop.
Our results showed a trend towards higher levels of N-glycosylation and trastuzumab resistance, but this did not reach statistical significance ( P = 0.081) ( Fig. 4c ).
2 C) showed a trend towards reduced frequency among offspring of supplemented mice ( Fig. 2 E), although this did not reach statistical significance.
In relation to smoking, women with MD showed a trend towards having more than a low frequency of “never smokers” (ND – 75.9%, MD – 68%) and a higher frequency of “quitters” (ND – 7.5%, MD – 14%), “smoking, attempt unsuccessfully to quit” (ND – 2.1%, MD – 6%), than those without D.
The oxylipin 13(S)-HODE showed a trend for treatment effect ( p value 0.0543) with similar direction as 9-HODE and 15-HETE.
Only the left SPL, which showed a trend in the block averaging analysis, also showed higher activity for the high motion than low motion sentences during the last two TR's of the block [ t (11) = 2.44, P = 0.03; Figure 3 ].
Patients with a psychiatric disorder and a history of severe symptoms (indicated by referral to the central mental hospital) showed a trend towards being more likely to have been tested for HIV compared to patients without referral (OR 2.3; CI = 0.96–5.91).
When spraying 1mM NaHSO 3 again, the changes in DF intensity showed a trend similar with that of the first NaHSO 3 treatment.
In general, data showed a trend where as the reaction volume increased, qPCR assays became slightly less efficient for all the assays with a plateau being reached at reaction master mix of 8 μl.
In a study conducted by Park and colleagues, IFN-γ showed a trend toward increase at CAPE treated group( 13 ).
The transfer of the four test drugs from circulation to breast milk, as indicated by M/P ratios obtained in vitro showed a trend similar to that seen in vivo at t max of each drug.
In addition, patients bearing the Dectin-2 rs7134303G allele showed a trend to have an increased risk for RA (OR = 1.35, 95%CI 1.00–1.83).
For regression analysis, we included all variables that showed a trend to significance or were significantly associated with ALD at univariate analysis.
Effects were more remarkable with pepstatin, as combination with MG132 showed synergy, with E64 showed a trend towards synergy, and with epoxomicin showed antagonism ( Figure 6 ).
There were also multiple SNPs that showed a trend towards association in the African American cohort.
Quantitation of SIV and IFNβ copies per microgram of DNA showed a trend of higher levels in unfixed cells compared to fixed cells although the difference was not significant ( Figure 5 ).
However, although urinary protein excretion after the study period showed a trend of increase in the control group, but a trend of decrease in the cilnidipine group, the difference in these changes was not statistically significant ( Table 4 ).
Although there were differences between the different religions when examining their relationship with ‘any smoking’, all religions showed a trend in the same direction.
In addition to increasing the M1 excitability, anodal tDCS improved motor signs assessed with UPDRS, which showed a trend of correlation with excitability changes.